They are associated
with tumor recurrence and metastasis, the lethal spreading of cancer to other organs.
Not exact matches
After adjusting for age,
tumor location, and stage, researchers from Cleveland Clinic's Dermatology & Plastic Surgery Institute discovered that women diagnosed
with malignant melanoma during their pregnancy or within one year of giving birth were 5.1 - times as likely to die, 6.9 - times as likely to experience metastasis, and 9.2 - times more likely to have a
recurrence.
«Surgery is the main treatment option for patients
with most solid
tumors, but
recurrence and metastasis remain significant problems,» says study senior author Michael Goldberg, PhD, assistant professor at Dana - Farber and Harvard Medical School.
Indeed, the authors point out that Ipilimumab might better effect
recurrence - free survival than adjuvant interferon and should be considered as an option by oncologists in this field considering its activity across subgroups including those
with high
tumor burden.
Of the 82 treated patients
with small
tumors, 96 percent (79 of 82) have had no
recurrence more than three years after treatment, and 80 percent (28 of 35) of those
with mid-size
tumors also have had no
recurrence.
A pre-surgery
tumor size of greater than three centimeters was associated
with worse LC, but local
recurrence was not significantly affected by the number of brain metastases or the patients» histology or graded prognosis assessments.
A new study by UCLA scientists has found that women diagnosed
with breast cancer and treated
with a one - week regimen of partial breast radiation after the surgical removal of the
tumor, or lumpectomy, saw no increase in cancer
recurrence or difference in cosmetic outcomes compared to women who received radiation of the entire breast for a period of up to six weeks after surgery.
«We found an association between increased breast cancer
recurrence in women
with a primary breast cancer
tumor that was positive for the IGF1 receptor, which is consistent
with other studies,» said Emond.
In their paper published online in the Journal of Clinical Oncology, the researchers report that several genetic characteristics of more aggressive
tumors were significantly more prevalent in African American patients and appeared to be associated
with a greater risk of
tumor recurrence.
«BMI1 plays a substantial role in many solid
tumors, including one of the most aggressive models of lung cancer, and its expression is linked
with tumor growth, invasion, metastasis, prognosis and
recurrence,» Levantini said.
Aside from
tumor recurrence, he could also be dealing
with organ rejection or a possible hormone imbalance if the
tumor is active.
The vaccine was administered to six patients
with melanoma whose
tumors had been removed by surgery and who were considered at high risk for
recurrence.
There was also variation based on histology,
with the highest rate of local
recurrence at about a year after surgery seen in malignant peripheral nerve sheath
tumors (MPNST), followed by myxofibrosarcoma; both those types saw persistently elevated rates compared to other subtypes out beyond 5 years.
Consequently, most patients
with advanced disease have died from a local
recurrence of their
tumor, even after aggressive treatment.
Radiation Therapy Prolongs Life in Men
with Recurrent Prostate Cancer Men whose
tumors recur after prostate cancer surgery are three times more likely to survive their disease long term if they undergo radiotherapy within two years of the
recurrence.
Slow down lymphoma growth modestly and show no effect on
tumor regression; delay
tumor recurrence with activation of p53; enhance
tumor regression and inhibit
tumor recurrence after alkylating drug therapy.
Local
tumor recurrence or
tumor progression can be delayed by months to years
with CFRT, and a local cure may be obtained in many instances.
Even
with aggressive surgery, the
tumor recurrence rate is very high (at least 50 % by 6 months after surgery).
Even
with treatment, no therapy for SCC is 100 percent effective and
tumor recurrence is high,
with approximately one in five horses experiencing cancer relapse.
If the implant proves to prevent mammary
tumor recurrence and you would like your rat to be implanted
with another deslorelin implant in a year, the cost of this implant will be at your charge.
When complete removal of the
tumor is not possible
with the partial ulnectomy, radiation therapy may be beneficial to prevent local
tumor recurrence.
For dogs
with large breast
tumors (> 3.0 cm), the prognosis tends to be poor since there is an 80 % chance of
recurrence of the
tumor within 6 months after canine breast cancer treatment.
The average survival in dogs
with axial osteosarcomas is 4 - 5 months, and the most common cause of treatment failure is local
tumor recurrence.
Even
with the primary mammary
tumor being surgically removed, spaying the pet greatly reduces the levels of estrogen and progesterone hormones which potentially further contributes to new mammary
tumor formation or
recurrence.
Those
with the greatest risk for
recurrence are those
with large, high grade (II & III), or those
with multiple
tumors.
In just the past two months a friend lost her sister to ovarian cancer; another friend was diagnosed
with prostate cancer; a high school friend died of throat cancer; a friend in her 20s had a
recurrence of the rare brain
tumor that... Continue Reading