The critical secondary endpoint of the change in retinal ganglion cell macular volume measured from baseline to week 48 demonstrated a statistically significant difference (p = 0.0189) between all GS010 - treated eyes and all sham - treated eyes,
with untreated eyes losing 0.038 cubic mm of macular ganglion cell volume while treated eyes preserved their ganglion cell volume -LRB--0.003 cubic mm).
The secondary endpoint of change in thickness of the temporal quadrant and papillomacular bundle of the retinal nerve fiber layer from baseline to week 48 demonstrated a large statistically significant difference (p = 0.0359) between all GS010 - treated eyes and all sham - treated eyes,
with untreated eyes showing a loss of 3.4 μm while treated eyes showed a limited loss of 0.6 μm.
Not exact matches
These individuals underwent
eye examinations every six months, out to two years post-treatment and the results were compared to an
untreated group
with early AMD.
Mice
with age - related and hereditary cataracts received drops in the right
eye, whereas the left
eye went
untreated.
Unexpectedly,
untreated contralateral
eyes (treated
with a sham injection) show a similar improvement of +11 ETDRS letters -LRB--0.211 LogMAR).
«Some breeders found selling to Georgia pet stores have serious Animal Welfare Act violations on their inspection reports including: dogs
with untreated, open wounds, severe
eye discharge, feces in food bowls and heavily matted fur.»
PSPCA found dogs
with missing
eyes and ears, sores and other
untreated skin conditions; many dogs had splayed feet from standing for hours, days on end, on wire floored cages.
she was rescued from a puppy mill and had
untreated glaucoma, infection and cherry
eye, along
with having had something imbedded in her neck.
It is critical to visit the vet if your pet is having issues
with their
eyes to prevent much more severe consequences if left
untreated, such as blindness.
Many were suffering from embedded chain collars, painful
untreated eye and dental infections, and severely matted coats encrusted
with fecal matter, among other conditions.
Some of the dogs are suffering from
untreated wounds — including one
with a severed limb —
eye and ear infections, dental disease and skin conditions.
In
untreated dogs or dogs
with more severe cases, the pup may cease all food intake, develop a discharge from the
eyes, and appear to experience seizures or other central nervous system issues.
The dogs seized were suffering from injuries including one
with a torn left
eye socket that was
untreated and left the dog blind.
Although details of her life before us were scant, I knew she'd come from a puppy farm in Wales and had been found seriously underweight,
with a prolapsed womb, teeth and skin infections, almost blinded by
untreated eye disease and cataracts and tied
with rope around her neck in the back of an old barn.
Oddly enough, one of the dogs purchased by the PSPCA at the Ohio auction three months later was a black Cocker Spaniel
with an
untreated cherry
eye in its left
eye from Zimmerman's kennels!
The investigators discovered that some breeders found selling to Georgia pet stores have serious Animal Welfare Act violations on their federal inspection records, including dogs
with untreated, open wounds; severe
eye discharge and heavily matted fur.
Along
with hearing loss, a chronic «dry -
eye» condition went
untreated, which may have contributed to her loss of vision.