She is involved
with vaccine design and efficacy screening in different models of mycobacterial infections.
Not exact matches
Armed
with that information, the researchers then
designed a mutant flu strain that was powerful enough to replicate well but highly susceptible to our body's own ability to control the virus — the ideal ingredients for a
vaccine.
This allows us to get the best of both worlds,
designing a
vaccine with a very high likelihood of success.»
Unlike any other
vaccine designed for human use, this product would be a DNA
vaccine that only contains a particular part of the pathogen (rather than a
vaccine with an inactivated live or dead virus, for example).
This situation leaves
vaccine investigators stuck
with inadequate study
designs.
«For instance, diagnostic tests could be tailored to different strains or stages of the disease,» and
vaccines could be
designed to skirt interaction
with the human body.
Most cancer
vaccines developed to date have been
designed to recognize and attack a specific known molecule — such as a cell - surface receptor — that is likely to be found on cancerous cells in any patient
with that type of tumor.
CTL119 manufacturing begins
with a patient's own T cells, some of which are removed and then reprogrammed in Penn's Clinical Cell and
Vaccine Production Facility
with a gene transfer technique
designed to teach the T cells to target and kill tumor cells.
Scientists say that the new
design may eliminate the problems
with the failed 2002
vaccine (manufactured by Elan Corporation, an Ireland - based drug company).
Equipped
with this deeper understanding, researchers are trying to make allergy
vaccines safer and more effective by
designing them to micromanage the allergic immune response.
Cynthia Lemere, a neurologist at Brigham and Women's Hospital and Harvard Medical School who researches Alzheimer's, points out another potential issue
with the
vaccine: Even
with the novel
design, it may not be enough to avoid the more aggressive immune response.
Kang's primary research focuses on
designing and developing effective
vaccines against viral diseases such as influenza virus and RSV, but he partnered
with a university and research institutes in South Korea that wanted international collaborative projects to study if ginseng can be used to improve health and protect against disease because of the potential benefit in fighting these viruses.
«We learned in this study that grabbing hold of these glycans can be a very important early step in an effective immune response to HIV, and
with this knowledge, we believe we can
design better candidate
vaccines,» said principal investigator Dennis R. Burton, professor of immunology and microbiology at TSRI.
Understanding how to elicit memory B cells, along
with plasmablasts, is critical for
designing effective
vaccines.
«Results from a former AIDS
vaccine study have shown that in a worst case scenario, immunization against HIV could enhance infection,» says Christiane Stahl - Hennig, who
designed the project in cooperation
with the former DPZ employee Sieghart Sopper.
The scientists
designed vaccines containing either the viral DNA
with the genetic blueprint for making this protein, or a section of the protein itself.
Led by University of Texas Austin researcher Dr Steve Bellan, and in collaboration
with the U.S. Centers for Disease Control and Prevention (CDC), the study on the
design of CDC's
vaccine trial in Sierra Leone is published in The Lancet Infectious Diseases.
«Uncovering the process by which neutralizing antibodies develop is critical to HIV
vaccine design,» said Elise Landais, Senior Research Scientist
with IAVI and lead author of the study.
Inspired by the earlier work, Deborah Fuller from the University of Washington in Seattle, USA, who is interested in developing influenza drugs and
vaccines, teamed up
with David Baker, also at the University of Washington, who is an expert in computational protein
design.
Working
with a world - leading group at the University of Connecticut in the USA, who pioneered the development of self - assembling protein nanoparticles (SAPNs) for
vaccine design, they have used advanced mathematical calculations to create a complete picture of the surface morphology of these particles.
Dr. Schief's work focuses on computation - guided and structure - based
design of immunogens and immunization regimens,
with the goal of inducing broadly neutralizing antibodies against HIV and other pathogens that have frustrated traditional
vaccine design strategies.
What if he
designed a similar
vaccine for dogs, but
with human DNA instead — would it be easier to get approval for this study?
Rama Rao Amara, a
vaccine researcher at Emory Vaccine Center and Yerkes National Primate Research Center, and Harriet Robinson, former head of microbiology and immunology at Yerkes and now chief scientific officer at the firm GeoVax, both described extra ingredients for the DNA / MVA vaccine that Robinson designed while at Yerkes in collaboration with NIH resea
vaccine researcher at Emory
Vaccine Center and Yerkes National Primate Research Center, and Harriet Robinson, former head of microbiology and immunology at Yerkes and now chief scientific officer at the firm GeoVax, both described extra ingredients for the DNA / MVA vaccine that Robinson designed while at Yerkes in collaboration with NIH resea
Vaccine Center and Yerkes National Primate Research Center, and Harriet Robinson, former head of microbiology and immunology at Yerkes and now chief scientific officer at the firm GeoVax, both described extra ingredients for the DNA / MVA
vaccine that Robinson designed while at Yerkes in collaboration with NIH resea
vaccine that Robinson
designed while at Yerkes in collaboration
with NIH researchers.
Historically, many
vaccines have been
designed to evoke an antibody response by B cells following innoculation
with weakened or dead pathogens.
Specifically, we will test samples from aged and, as a control, younger human subject before and after vaccination
with the trivalent inactivated influenza
vaccine (TIV) in an exploratory / confirmatory study
design to assess age - related responsiveness to the
vaccine.
Before joining IDRI, Tracey worked as a Protocol Development Manager
with the HIV
Vaccine Trials Network at the Fred Hutchinson Cancer Research Center where she led multi-disciplinary teams in the
design and implementation of clinical trials evaluating candidate HIV and tuberculosis
vaccines.
Historically, many
vaccines have been
designed to evoke an antibody response by B cells following inoculation
with weakened or dead pathogens.
The space was also
designed with the public in mind, featuring interactive tour stops throughout the lab space that use technology to underscore IDRI's work in developing
vaccines, drugs and diagnostics, as well as large built - in windows to showcase IDRI's specialized facilities, including manufacturing.
Many researchers at NIH, universities and medical schools are looking for antibodies that act on a broad range of flu strains,
with the goal of understanding how they attach to the viruses and then
designing vaccines or other flu therapies that produce a similar effect.
Physicians
with the Personalized Medicine Program at The Tisch Cancer Institute have initiated a phase I proof - of - concept study, a fully personalized multipeptide therapeutic
vaccine designed to target tumor - derived neoantigens for individual patients.
With a new properly designed facility, our vaccine clinics could essentially double by providing 30,000 affordable vaccinations each year — which will keep pets healthy and compliant with the
With a new properly
designed facility, our
vaccine clinics could essentially double by providing 30,000 affordable vaccinations each year — which will keep pets healthy and compliant
with the
with the law.
The Mobile
Vaccine Clinic (Care - A-Van) is a true mobile vaccine service designed to provide pet owners with convenient access to low - cost vaccines and products to keep their dogs and cats h
Vaccine Clinic (Care - A-Van) is a true mobile
vaccine service designed to provide pet owners with convenient access to low - cost vaccines and products to keep their dogs and cats h
vaccine service
designed to provide pet owners
with convenient access to low - cost
vaccines and products to keep their dogs and cats healthy.
Vaccination Days are «deli style» first come - first served slots
designed to provide healthy pets
with their core
vaccines and routine tests.
The Care - A-Van is
designed to provide pet owners
with convenient access to low - cost
vaccines and products to keep their dogs and cats healthy.
Care - A-Van is a true mobile
vaccine service
designed to provide pet owners
with convenient access to low - cost
vaccines and products to keep their dogs and cats healthy.
In addition to the spay and neuter clinic, Pawmetto Lifeline's Care - A-Van Mobile
Vaccine Service is
designed to provide pet owners
with convenient access to low - cost
vaccines and products to keep their dogs and cats healthy.
Essential plans are
designed to provide owners
with a means of budgeting for wellness examinations,
vaccines, parasite control, recommended wellness testing and micro-chipping.
develops autonomous drones
designed to deliver
vaccines, medicine and blood on request from health workers in rural areas,
with the Tanzanian government to begin using more than 100 drones from four distribution centers to make up to 2,000 deliveries each day.
Zipline develops autonomous drones
designed to deliver
vaccines, medicine and blood on request from health workers in rural areas,
with the Tanzanian government to begin using more than 100 drones from four distribution centers to make up to 2,000 deliveries each day.
Strong background in molecular biology / cell biology
with emphasis on virology, cell cultures, viral vectors, protein
design and
vaccine.
Accomplished and highly motivated research professional
with extensive experience in infectious disease (hepatitis C virus (HCV), Respiratory syncytial virus (RSV), dengue viruses, Herpes virus (HSV) and influenza viruses) in
vaccine development, assay
design, development and validation / verification molecular diagnostic assay (MGB - Pleiades chemistry).