Sentences with phrase «with vaccine design»

She is involved with vaccine design and efficacy screening in different models of mycobacterial infections.

Not exact matches

Armed with that information, the researchers then designed a mutant flu strain that was powerful enough to replicate well but highly susceptible to our body's own ability to control the virus — the ideal ingredients for a vaccine.
This allows us to get the best of both worlds, designing a vaccine with a very high likelihood of success.»
Unlike any other vaccine designed for human use, this product would be a DNA vaccine that only contains a particular part of the pathogen (rather than a vaccine with an inactivated live or dead virus, for example).
This situation leaves vaccine investigators stuck with inadequate study designs.
«For instance, diagnostic tests could be tailored to different strains or stages of the disease,» and vaccines could be designed to skirt interaction with the human body.
Most cancer vaccines developed to date have been designed to recognize and attack a specific known molecule — such as a cell - surface receptor — that is likely to be found on cancerous cells in any patient with that type of tumor.
CTL119 manufacturing begins with a patient's own T cells, some of which are removed and then reprogrammed in Penn's Clinical Cell and Vaccine Production Facility with a gene transfer technique designed to teach the T cells to target and kill tumor cells.
Scientists say that the new design may eliminate the problems with the failed 2002 vaccine (manufactured by Elan Corporation, an Ireland - based drug company).
Equipped with this deeper understanding, researchers are trying to make allergy vaccines safer and more effective by designing them to micromanage the allergic immune response.
Cynthia Lemere, a neurologist at Brigham and Women's Hospital and Harvard Medical School who researches Alzheimer's, points out another potential issue with the vaccine: Even with the novel design, it may not be enough to avoid the more aggressive immune response.
Kang's primary research focuses on designing and developing effective vaccines against viral diseases such as influenza virus and RSV, but he partnered with a university and research institutes in South Korea that wanted international collaborative projects to study if ginseng can be used to improve health and protect against disease because of the potential benefit in fighting these viruses.
«We learned in this study that grabbing hold of these glycans can be a very important early step in an effective immune response to HIV, and with this knowledge, we believe we can design better candidate vaccines,» said principal investigator Dennis R. Burton, professor of immunology and microbiology at TSRI.
Understanding how to elicit memory B cells, along with plasmablasts, is critical for designing effective vaccines.
«Results from a former AIDS vaccine study have shown that in a worst case scenario, immunization against HIV could enhance infection,» says Christiane Stahl - Hennig, who designed the project in cooperation with the former DPZ employee Sieghart Sopper.
The scientists designed vaccines containing either the viral DNA with the genetic blueprint for making this protein, or a section of the protein itself.
Led by University of Texas Austin researcher Dr Steve Bellan, and in collaboration with the U.S. Centers for Disease Control and Prevention (CDC), the study on the design of CDC's vaccine trial in Sierra Leone is published in The Lancet Infectious Diseases.
«Uncovering the process by which neutralizing antibodies develop is critical to HIV vaccine design,» said Elise Landais, Senior Research Scientist with IAVI and lead author of the study.
Inspired by the earlier work, Deborah Fuller from the University of Washington in Seattle, USA, who is interested in developing influenza drugs and vaccines, teamed up with David Baker, also at the University of Washington, who is an expert in computational protein design.
Working with a world - leading group at the University of Connecticut in the USA, who pioneered the development of self - assembling protein nanoparticles (SAPNs) for vaccine design, they have used advanced mathematical calculations to create a complete picture of the surface morphology of these particles.
Dr. Schief's work focuses on computation - guided and structure - based design of immunogens and immunization regimens, with the goal of inducing broadly neutralizing antibodies against HIV and other pathogens that have frustrated traditional vaccine design strategies.
What if he designed a similar vaccine for dogs, but with human DNA instead — would it be easier to get approval for this study?
Rama Rao Amara, a vaccine researcher at Emory Vaccine Center and Yerkes National Primate Research Center, and Harriet Robinson, former head of microbiology and immunology at Yerkes and now chief scientific officer at the firm GeoVax, both described extra ingredients for the DNA / MVA vaccine that Robinson designed while at Yerkes in collaboration with NIH reseavaccine researcher at Emory Vaccine Center and Yerkes National Primate Research Center, and Harriet Robinson, former head of microbiology and immunology at Yerkes and now chief scientific officer at the firm GeoVax, both described extra ingredients for the DNA / MVA vaccine that Robinson designed while at Yerkes in collaboration with NIH reseaVaccine Center and Yerkes National Primate Research Center, and Harriet Robinson, former head of microbiology and immunology at Yerkes and now chief scientific officer at the firm GeoVax, both described extra ingredients for the DNA / MVA vaccine that Robinson designed while at Yerkes in collaboration with NIH reseavaccine that Robinson designed while at Yerkes in collaboration with NIH researchers.
Historically, many vaccines have been designed to evoke an antibody response by B cells following innoculation with weakened or dead pathogens.
Specifically, we will test samples from aged and, as a control, younger human subject before and after vaccination with the trivalent inactivated influenza vaccine (TIV) in an exploratory / confirmatory study design to assess age - related responsiveness to the vaccine.
Before joining IDRI, Tracey worked as a Protocol Development Manager with the HIV Vaccine Trials Network at the Fred Hutchinson Cancer Research Center where she led multi-disciplinary teams in the design and implementation of clinical trials evaluating candidate HIV and tuberculosis vaccines.
Historically, many vaccines have been designed to evoke an antibody response by B cells following inoculation with weakened or dead pathogens.
The space was also designed with the public in mind, featuring interactive tour stops throughout the lab space that use technology to underscore IDRI's work in developing vaccines, drugs and diagnostics, as well as large built - in windows to showcase IDRI's specialized facilities, including manufacturing.
Many researchers at NIH, universities and medical schools are looking for antibodies that act on a broad range of flu strains, with the goal of understanding how they attach to the viruses and then designing vaccines or other flu therapies that produce a similar effect.
Physicians with the Personalized Medicine Program at The Tisch Cancer Institute have initiated a phase I proof - of - concept study, a fully personalized multipeptide therapeutic vaccine designed to target tumor - derived neoantigens for individual patients.
With a new properly designed facility, our vaccine clinics could essentially double by providing 30,000 affordable vaccinations each year — which will keep pets healthy and compliant with the With a new properly designed facility, our vaccine clinics could essentially double by providing 30,000 affordable vaccinations each year — which will keep pets healthy and compliant with the with the law.
The Mobile Vaccine Clinic (Care - A-Van) is a true mobile vaccine service designed to provide pet owners with convenient access to low - cost vaccines and products to keep their dogs and cats hVaccine Clinic (Care - A-Van) is a true mobile vaccine service designed to provide pet owners with convenient access to low - cost vaccines and products to keep their dogs and cats hvaccine service designed to provide pet owners with convenient access to low - cost vaccines and products to keep their dogs and cats healthy.
Vaccination Days are «deli style» first come - first served slots designed to provide healthy pets with their core vaccines and routine tests.
The Care - A-Van is designed to provide pet owners with convenient access to low - cost vaccines and products to keep their dogs and cats healthy.
Care - A-Van is a true mobile vaccine service designed to provide pet owners with convenient access to low - cost vaccines and products to keep their dogs and cats healthy.
In addition to the spay and neuter clinic, Pawmetto Lifeline's Care - A-Van Mobile Vaccine Service is designed to provide pet owners with convenient access to low - cost vaccines and products to keep their dogs and cats healthy.
Essential plans are designed to provide owners with a means of budgeting for wellness examinations, vaccines, parasite control, recommended wellness testing and micro-chipping.
develops autonomous drones designed to deliver vaccines, medicine and blood on request from health workers in rural areas, with the Tanzanian government to begin using more than 100 drones from four distribution centers to make up to 2,000 deliveries each day.
Zipline develops autonomous drones designed to deliver vaccines, medicine and blood on request from health workers in rural areas, with the Tanzanian government to begin using more than 100 drones from four distribution centers to make up to 2,000 deliveries each day.
Strong background in molecular biology / cell biology with emphasis on virology, cell cultures, viral vectors, protein design and vaccine.
Accomplished and highly motivated research professional with extensive experience in infectious disease (hepatitis C virus (HCV), Respiratory syncytial virus (RSV), dengue viruses, Herpes virus (HSV) and influenza viruses) in vaccine development, assay design, development and validation / verification molecular diagnostic assay (MGB - Pleiades chemistry).
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