Sentences with phrase «with vaccinia»

«The novelty here, with vaccinia, is that it's not just preventing the virus superinfecting, but physically it's repelling the virus away,» says Smith, whose team reports its findings today in Science.

When researchers infected these ERV - depleted cells with the vaccinia virus (which may be related to smallpox), they had a much weaker innate immune response than unedited normal cells, the team reports online today in Science.

Not exact matches

Lederman, who says he's «obsessed» with Jenner and has been working on a biography of the scientist for 20 years, is convinced that Jenner's original vaccine, now named vaccinia, was derived from a virus circulating in horses, not cows, as folklore has it.

Replication of vaccinia is the first step to killing cancer cells and shrinking tumors with this approach.

However, the classic smallpox vaccine, a weakened poxvirus called vaccinia, can cause serious side effects and even death in people with compromised immune systems, eczema, or atopic dermatitis.

Over one month, 30 people with an advanced form of hepatocellular carcinoma — the most common type of liver cancer — received three doses of a genetically engineered version of the vaccinia virus.

(D) The average number of somatic hypermutations in the pandemic H1N1 patient plasmablast variable region genes compared with primary IgG plasmablast responses to vaccinia (small pox) or the anthrax vaccine, or after at least 4 boosters with the anthrax vaccine.

[3] Odunsi K, Matsuzaki J, Karbach J, Neumann A, Mhawech - Fauceglia P, Miller A, Beck A, Morrison CD, Ritter G, Godoy H, Lele S, duPont N, Edwards R, Shrikant P, Old LJ, Gnjatic S, Jäger E. Efficacy of vaccination with recombinant vaccinia and fowlpox vectors expressing NY - ESO - 1 antigen in ovarian cancer and melanoma patients.

Late last week, FDA worked with the United States Attorney to ask a court to seize the components of a product that involved the use of vaccinia virus vaccine as part of a purported treatment for cancer that FDA believes created the potential for substantial risks to patients.

On March 3, 2007, a two - year - old boy suffering from severe eczema and an unusual, widespread rash was transferred from St. Catherine's Hospital, in East Chicago, IN, to the University of Chicago's Comer Children's Hospital where he was diagnosed with eczema vaccinatum — a rare, severe, adverse reaction to the vaccinia virus.

Differences and similarities in viral life cycle progression and host cell physiology after infection of human dendritic cells with modified vaccinia virus Ankara and vaccinia virus.

Raised in mice primed with a SIVmac251 gp160 vaccinia recombinant (vAbT253), and boosted with glutaraldehyde - fixed SIVmac11 / 88 from C8166 cells.

Prime - boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against Plasmodium falciparum infection in Kenyan adult.

In another report, vaccinia was used as a vector vaccine for immunizing Balb / c mice with each of the SARS - CoV structural proteins (N, S, membrane, and envelope) and then challenged with SARS - CoV [21].

Odunsi K, Matsuzaki J, Karbach J, Neumann A, Mhawech - Fauceglia P, Miller A, Beck A, Morrison CD, Ritter G, Godoy H, Lele S, Dupont N, Edwards R, Shrikant P, Old LJ, Gnjatic S, Jager E. (2012) Efficacy of vaccination with recombinant vaccinia and fowlpox vectors expressing NY - ESO - 1 antigen in ovarian cancer and melanoma patients.

To do this, a team led by Matthew Weitzman of the University of Pennsylvania crosslinked the host factors of infected human cells with the DNA of adenovirus, herpes simplex virus and vaccinia virus.

MHRP scientists, working with NIAID, have developed an attenuated viral vector — modified vaccinia Ankara — vaccine candidate, MVA - CMDR (HIV - 1 CM235 env / CM240 gag - pol).

Temperature - sensitive mutants with lesions in the vaccinia virus F10 kinase undergo arrest at the earliest stage of virion morphogenesis.