Sentences with phrase «with valproate»

Compared to children whose mothers did not have epilepsy, the risk of autism was seven times higher in those with valproate exposure.
In patients who have a «Met» variant of COMT, rising levels of proline appeared to do the exact opposite: these patients had more or worse negative symptoms, and the symptoms did not improve with valproate.
Among those patients who were being treated with valproate (approximately one - third of the schizophrenia patients), negative symptoms were more severe in those with the Met / Met gene than in those with the Val / Val gene.
The researchers also evaluated negative symptoms in 43 patients with bipolar disorder, about half of whom were treated with valproate.

Not exact matches

The study helps determine the effects of CBD in combination with common AEDs, including carbamazepine, valproate, levetiracetam, clobazam and lacosamide.
«This information may help to determine which patients may be most likely to benefit from treatment with mood stabilizers such as valproate that are known to modulate proline levels.»
The authors conclude that valproate may be effective for treating negative symptoms in psychiatric patients with two copies of the «Val» variant of the COMT gene, which breaks down dopamine in the brain.
Of these 171 women, 42 had taken levetiracetam, 27 had taken topirimate and 47 had taken valproate while pregnant — an additional control group of women with similarly - aged children who had not taken any antiepileptic drug while pregnant was also included in the study.
In the roughly 40 percent of patients with this genotype, higher levels of proline (a neuromodulator that is increased by valproate), correlated with fewer negative symptoms.
Valproate, one of the most commonly prescribed antiepileptic medications, has been associated in the past with birth defects and developmental problems.
The study of 6,671 individuals found lower rates of self - harm and unintentional injuries among those patients taking lithium compared with those prescribed valproate, olanzapine or quetiapine.
A common mood - stabilizing drug, valproate, is found to control manic - like behavior induced in mice with an extra copy of a gene called SHANK3
Neural tube malformations are most common with the use of Valproate, a folic acid antagonist.
Study of the effect of valproate on pulmonary cancer cells, in combination with chemotherapy agents.
By Kate Stinchfield MONDAY, Dec. 1, 2008 (Health.com)-- Pregnant women who take the epilepsy drug valproate may be more likely to have a child with autism than those who don't take the seizure - controlling drug, according to a study published Monday in the journal Neurology.
Patients with bipolar disorder were being treated with mood stabilizing agents (i.e., lithium, valproate, or lamotrigine) with or without atypical antipsychotics.
Valproate reduces alcohol consumption in people with comorbid alcohol dependency and bipolar disorder
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