Sentences with phrase «within microfluidic»

The primary epithelial cells are expanded as 3D organoids, dissociated, and cultured on a porous membrane within a microfluidic device with human intestinal microvascular endothelium cultured in a parallel microchannel under flow and cyclic deformation.

Based on this change, you can use this technique to measure the mass of the biomolecule, and confirm whether it survives exposure to ionized gas during encapsulation within the microfluidic platform.

This sensor was used to demonstrate that biomolecules can be successfully sealed within microfluidic devices.

Measuring two fundamental properties of surface chemical reactions on the same device means that researchers can be far more confident that biomolecules have been successfully encapsulated within the microfluidic platform.

«This means that the system will open up new options for biosensing particles within microfluidic devices.»

To study this barrier and determine why a lack of blood flow causes it to leak, the researchers built a blood - vessel - on - a-chip model consisting of a channel lined with a layer of human endothelial cells surrounded by extracellular matrix within a microfluidic device, which allowed them to easily simulate and control the flow of blood through a vessel and evaluate the cells» responses.

To prove their concept of this multiplex spectral microgel analysis within a microfluidic flow, the team used «different barcodes corresponding to different emissions at specific wavelengths and the fluorescence intensity of known microRNA concentration,» which was measured for calibrations of the specific microRNA being explored.

By using thin (350 μm) ferromagnetic poles, localized actuation regions can be achieved within the microfluidic channels.

With this method, they created a three - dimensional array of permeable carbon nanotubes within a microfluidic device, through which fluid can flow.

The device continuously monitors conditions within the microfluidic chip, including oxygen levels, temperature, and pH, to ensure the optimum environment for cell growth.

As it can take weeks to grow human cells into intact differentiated and functional tissues within Organ Chips, such as those that mimic the lung and intestine, and researchers seek to understand how drugs, toxins or other perturbations alter tissue structure and function, the team at the Wyss Institute for Biologically Inspired Engineering led by Donald Ingber has been searching for ways to non-invasively monitor the health and maturity of cells cultured within these microfluidic devices over extended times.

Not exact matches

The study indicated that the proteins are readily measurable with standard assays, but the team hopes to develop a microfluidic chip that can derive reliable readings within just two hours (well within the duration of many emergency room visits).

The cells are held within a millimeter - scale table - top microbioreactor, containing a microfluidic chip, which was originally developed by Rajeev Ram, a professor of electrical engineering at MIT, and his team, and then commercialized by Kevin Lee — an MIT graduate and co-author — through a spin - off company.

They then grouped the nanotubes into a cylinder - shaped forest, measuring about 50 micrometers tall and 1 millimeter wide, and centered the array within a 3 millimeter - wide, 7 - millimeter long microfluidic channel.

The effectiveness of the platelet - like particles has been tested in an animal model and in a microfluidic chamber designed to simulate conditions within the body's circulatory system.

«We even succeeded in inducing much of this differentiation process within a channel of the microfluidic chip, whereby applying cyclical motions that mimic the rhythmic deformations living glomeruli experience due to pressure pulses generated by each heartbeat, we achieve even greater maturation efficiencies.»

«These mechanical vibrations can, in turn, «talk» to liquids within the hollow device and provide optical readout of the mechanical properties,» said Bahl, who is first author of the paper, «Brillouin cavity optomechanics with microfluidic devices,» published this week in Nature Communications.

Our goal is to create a microfluidic 3D cell culture system representing a «placenta - on - a-chip» in order to mimic the nutrient / waste transfer between maternal blood and fetal blood that occurs in the cotyledon section of the placenta, and to test and observe the effects of ethanol within the maternal bloodstream and compare it to a similar in vivo situation.