Sentences with phrase «without affecting cell»

Based on analyses of over 600 drug and breast cancer cell pairings, researchers showed that, for some cells, drug exposure can cause significant changes in gene expression — indicating the successful action of a drug on its target — without affecting cell growth or survival.

Importantly, the ligands impaired myofibroblast function without affecting cell viability.

Tasoglu and Demirci also demonstrated that micro-robotic construction of cell - encapsulating hydrogels can be performed without affecting cell vitality and proliferation.

Not exact matches

Charlie inherited the faulty RRM2B gene from his parents, affecting the cells responsible for energy production and respiration and leaving him unable to move or breathe without a ventilator.

The method is safer and has more precision since it only targets fat cells in the affected area therefore it promises cellulite removal without causing any harm to your skin.

In the article, Dr. Margot Sunderland, author of the best - selling book What Every Parent Needs To Know, stated that leaving a child in a state of distress for a prolonged period without offering comfort affects them on a cellular level, specifically the «migration» of their cells as they get to where they need to be.

The cells suppress the immune response in the livers of mice, without affecting the rest of the immune system.

In a study published in March in Nature Immunology, Dr. Melnick and his team reported that it is possible to shut down Bcl6 in DLBCL without affecting its vital role in the T cells and macrophages needed to support a healthy immune system.

The cells grew into networks over the material without affecting its optical properties.

«How can we promise we will cure something without knowing precisely how tissue and cells work and how they are affected by a disease?

The rapid drop in circulating T cells during sleep «show [s] that even one night without sleep affects the adaptive immune system,» says first author Luciana Besedovsky.

Eric Strohm at Ryerson University in Toronto, Canada, used laser light to heat the protein haemoglobin within red blood cells without affecting the surroundings.

These cells, in turn, instruct factor - VIII — specific immune cells to become tolerant to the coagulation protein, resulting in suppression of misdirected antibody responses to the replacement therapy — all without affecting the rest of the immune system.

One of these compounds enabled chloride transport in real cells without seriously affecting lysosomal pH.

And astronomers illuminate their sky charts with red light, which makes objects visible to the cone cells without affecting the red - blind rod cells and forcing the dark - adaptation process to begin all over again.

To understand how the bacteria affected the immune system, the researchers grew L. reuteri in liquid and then transferred small amounts of the liquid — without bacteria — to immature immune cells isolated from mice.

To examine how the availability of food may have affected armed conflict in Africa, the study relies on PRIO - Grid data from over 10,600 grid cells in Africa from 1998 to 2008, new agricultural yields data from EarthStat and Armed Conflict Location and Event Dataset, which documents incidents of political violence, including those with and without casualties.

It targets the CD52 glycoproteins on the surface of mature immune cells, or lymphocytes, depleting levels of the aggressive T and B cells without affecting other lymphocytes.

Also, unlike chemical manipulators that diffuse throughout a cell, light can be applied to specific genes without affecting other parts of the cell.

In other words, the researchers achieved incredibly localized heating of cell membranes without affecting the rest of the cell.

A trained robotic surgeon experienced in the treatment of prostate, bladder and kidney cancer, Assoc Prof Chia said, «For anticancer drugs to achieve their best effectiveness, they need to penetrate into the tumour efficiently in order to reach the cystoplasm of all the cancer cells that are being targeted without affecting the normal cells.

As a prelude to introducing genes whose products would be therapeutically useful in cancer, the researchers say they have successfully introduced a harmless gene from bacteria into TILs without affecting the behaviour of the cells (Proceedings of the National Academy of Sciences, vol 87, p 473).

My colleagues and I at the Wellcome Trust Sanger Institute and the Laboratory of Regenerative Medicine, University of Cambridge analysed the way this membrane affects stem cells and are now looking at how they effect heart muscle cells, and found that it might be able to change the way cells behave, without all the trouble of altering their genetic code.

Depletion of neutrophils blocks the recruitment of antigen non-specific cells into the liver without affecting the antiviral activity of hepatitis B virus - specific cytotoxic T lymphocytes.

You can see that the search for new antibiotics occurs down at the enzyme level, hunting for differences between the enzymes in human and bacterial cells that can be exploited to kill bacteria without affecting human cells.

Depletion of neutrophils blocks the recruitment of antigen - nonspecific cells into the liver without affecting the antiviral activity of hepatitis B virus - specific cytotoxic T lymphocytes.

Cbl - b regulates antigen - induced TCR down - regulation and IFN - gamma production by effector CD8 T cells without affecting functional avidity.

Whilst the supplements did not affect maximal oxygen uptake or the results of a 20 metre shuttle test, the results showed that markers for the production of new muscle mitochondria — the power supply for cells — increased only in the group without supplements.

Macrophage depletion alters the blood — nerve barrier without affecting Schwann cell function after neural injury.

Do Plasma Cells Affect Hemoglobin and Red Blood Cell Counts in Patients With and Without Myeloma?

Also, intracellular milieu (ICM) is linked to extracellular milieu (ECM), what goes inside the cells also affects ECM because they are tied together and in communication; but also ECM is created by the ICM; for example, without fibroblast or stromal cells, for example, there wouldn't be much ECM or ECM scaffold formation in the first place; for they are key elements for ECM existing in the first place.

Acquired tumor cell resistance to sunitinib causes resistance in a HT - 29 human colon cancer xenograft mouse model without affecting sunitinib biodistribution or the tumor microvasculature

Through computer analysis they were able to modify the chemical makeup of the compounds and find the precise formulation for creating the strongest bond between the compound and the kappa opioid receptor without affecting any other receptors in the cell.

Another challenge was finding molecules that selectively targeted the ULK1 enzyme without affecting healthy cells.

Thanks to I - chlor's photosensitizing property, laser light of specific wavelengths applied to a tumor containing it causes cancer cells to overheat, killing them without affecting normal cells.

Kucherlapati: Without thinking about modifying the human genome line, would this technology have the ability to affect the health of humans by modifying the stem cells?

They also improve immune functions by enhancing the natural killer cells that hunt down and dispose of cancer cells without affecting normal cells.

A Korean study from 2007 acknowledged that vitamin C «is considered a safe and effective therapy» 225 and a 2008 study from the National Institutes of Health found that high - doses of vitamin C displayed «cytotoxicity toward a variety of cancer cells in vitro without adversely affecting normal cells.»

The fruit works against cancer by being cytotoxic to malignant cancer cells without affecting the normal, healthy cells.

Citrus aurantium has a rare combination of 5 amines: synephrine, N - methyltyramine, hordenine, octopamine, and tyramine, which «stimulates beta - 3 cell receptors» that could lead to increase in your metabolic rate without affecting heart rate or blood pressure.

It can also kill many different types of cancer cells by triggering apoptosis (programmed cell death) without affecting normal cells.

Some studies suggested that certain chemicals present in peaches may be able to inhibit the growth of cancer cells without affecting normal body cells — unlike chemotherapy, which is highly effective but unable to discriminate between healthy cells and cancer.

MIT developed this breakthrough solar cell that can be placed on virtually any surface without affecting it.