Sentences with phrase «without animal model»

These are valuable, life - saving advances that would be impossible without animal model research.

«This is something the hepatitis C field is in dire need of,» says Stanley Lemon of the University of North Carolina in Chapel Hill, as it is very difficult to develop a vaccine without an animal model.

Patrik Verstreken: «Our research into brain diseases is not possible without animal models.

Not exact matches

«That means we can study such brain states in animal models like flies or mice without worrying about whether they have «feelings» or not.

Their findings, published recently in the journal Blood, show that animal models without this enzyme experience dangerous HSC activation and ultimately succumb to lethal anemia.

We also want to use this system to explore which substances could counteract the progress of neurodegeneration in the brain without having to use animal models at this early stage.

The nontoxic MRI probe was delivered intranasally to mouse models with Alzheimer's disease and control animals without the disease.

Phenotypic approaches screen for the effects of small molecules on an observable characteristic of an animal, tissue or cell model, typically without a priori knowledge of the target.

While the findings have only been seen in animals models so far, Zeng said that successful translation of the regimen into clinical application in humans may represent a novel approach that allows strong anti-cancer effects without causing GVHD.

Over the last few years, scientists have been able to recreate accurate models of human organs by embedding living tissue onto chips, allowing them to study the effects of drugs and diseases without testing on animals or humans.

There is a growing need for animal models to carry out research studies without putting human individuals at risk.

«But surprisingly, in the animal models, GFAP was turning over more quickly in animals with Alexander disease mutations than in ones without those mutations.»

This allowed for them to study infection in a model highly related to humans but without the need to infect a living animal.

However, a new study conducted in an animal model at Wake Forest Baptist Medical Center showed that fructose rapidly caused liver damage even without weight gain.

If we equate de facto ketogenic diets with high - protein diets (which is not always correct) then the risks proposed by critics of this type of dietary approach are essentially those of possible kidney damage due to high levels of nitrogen excretion during protein metabolism, which can cause an increase in glomerular pressure and hyperfiltration.12 There is not wide agreement between studies; however, some infer the possibility of renal damage from animal studies, 99, 100 whereas others, looking at both animal models, meta - analyses and human studies, propose that even high levels of protein in the diet do not damage renal function.101, 102 In subjects with intact renal function, higher dietary protein levels caused some functional and morphological adaptations without negative effects.103 There may actually be renal - related effects, but on blood pressure rather than morphological damage.

Or, while you were trying to catch a shot of that rare bird — read street style photographers getting models - off - duty — you realize you are crossing a caravan of wild animals... Yeah you were actually crossing 9th Avenue without knowing it.

Without utilizing the admissions by appointment model, we are not able to anticipate how many animals will come into our care after being surrendered by their owners.

Translating the above to climate science, if you tell me that in 100 years earth inhabited by your children is going to hell in a handbasket, because our most complicated models built with all those horrendously complicated equestions you can find in math, show that the global temperatures will be 10 deg higher and icecaps will melt, sea will invade land, plant / animal ecosystem will get whacked out of order causing food supply to be badly disrupted, then I, without much climate science expertise, can easily ask you the following questions and scrutinize the results: a) where can I see that your model's futuristic predictions about global temp, icecaps, eco system changes in the past have come true, even for much shorter periods of time, like say 20 years, before I take this for granted and make radical changes in my life?