301 chronically infected adults were treated with the ravidasvir / sofosbuvir combination for 12 weeks for patients
without cirrhosis of the liver, and for 24 weeks for those with compensated cirrhosis.
Overall, an indication of a non-quantifiable added benefit can be derived from the dossier for three patient groups: patients
without cirrhosis of the liver infected with genotype 1a (treatment - naive and treatment - experienced) and with genotype 1b who have not been pretreated.
Not exact matches
Beta alcoholism is characterized by such nutritional deficiency diseases as gastritis,
cirrhosis of the
liver, and polyneuropathy,
without loss
of control, withdrawal, or other addictive manifestations.
Most carriers live for many years
without major health problems, but some develop severe
liver damage (
cirrhosis) or cancer
of the
liver.
This recommendation comes from the Valence study where high SVR rates were seen in those who had no previous HCV treatment history,
without or with scarring
of the
liver, known as
cirrhosis (93 % and 92 %, respectively).
Results presented today at The International
Liver Congress ™ 2015 demonstrate that hepatitis C (HCV)- infected genotype - 3 (GT - 3) patients, with and
without cirrhosis, receiving 24 weeks
of sofosbuvir (SOF) in combination with ribavirin (RBV) and peginterferon (PEG) achieved the highest sustained virologic response rates at 12 weeks (SVR12), observed in a Phase 3 study, to date.
The single - center retrospective study was conducted in 644 patients diagnosed as HBeAg - positive chronic HBV (an indicator
of active viral replication) with alanine aminotransferase levels within two times
of upper normal limit,
without evidence
of liver cirrhosis.
«
Liver cancer is on the rise worldwide, and in human studies we've now seen that patients can progress from fatty liver disease to liver cancer without any middle steps such as cirrhosis,» says David Moore, a professor of molecular and cellular biology, who led the study with Associate Professor Loning Fu, both at Ba
Liver cancer is on the rise worldwide, and in human studies we've now seen that patients can progress from fatty
liver disease to liver cancer without any middle steps such as cirrhosis,» says David Moore, a professor of molecular and cellular biology, who led the study with Associate Professor Loning Fu, both at Ba
liver disease to
liver cancer without any middle steps such as cirrhosis,» says David Moore, a professor of molecular and cellular biology, who led the study with Associate Professor Loning Fu, both at Ba
liver cancer
without any middle steps such as
cirrhosis,» says David Moore, a professor
of molecular and cellular biology, who led the study with Associate Professor Loning Fu, both at Baylor.