Sentences with phrase «without tyrosine phosphorylation»
In this study, we provide the first evidence that in STAT1 - deficient U3A cells, STAT2 forms a complex with IRF - 9 on the ISRE regions of RIG - G promoter and effectively mediates the transcription of RIG - G gene, even without the tyrosine phosphorylation.
http://cancerres.aacrjournals.org/
Recently, accumulating observations support the notion that STAT proteins can drive gene expression without tyrosine phosphorylation (14 — 19).
During the past decade, data on the putative roles of STAT proteins in mediating gene expression without tyrosine phosphorylation have been accumulating.