We calculated these transition probabilities using data from the longitudinal National Health and Nutrition Evaluation Survey, which assessed a cohort of
women in 1987 and the same
women again
in 1992.25 Several limitations of these data
affect our model: 1) because this national survey lacks data on
women before
age 35 years,
women in our model could not develop hypertension, type 2 diabetes mellitus, or MI before
age 35 years; 2) because longitudinal survey data were only available for a 5 - year interval, we assumed that transition probabilities were stable within the 5 - year intervals and converted these probabilities from 5 - year to 1 - year intervals; 3) because the survey data were too few to provide stable estimates by year of
age, we used transition probabilities for
women in three
age groups:
aged 50 years and younger, 51 — 65 years, and 65 years and older.
In contrast, the allele's frequency in women and in people from Northern California did not vary with age, presumably because fewer in these groups smoked heavily and the allele did not affect their surviva
In contrast, the allele's frequency
in women and in people from Northern California did not vary with age, presumably because fewer in these groups smoked heavily and the allele did not affect their surviva
in women and
in people from Northern California did not vary with age, presumably because fewer in these groups smoked heavily and the allele did not affect their surviva
in people from Northern California did not vary with
age, presumably because fewer
in these groups smoked heavily and the allele did not affect their surviva
in these
groups smoked heavily and the allele did not
affect their survival.