Sentences with phrase «work against the targets»

It simply does not work against the targets flying at heights of below ~ 60 meters.

Not exact matches

The hype preceding Target's arrival now works against every other beloved American brand that makes a Canadian foray.

One of the many tactics that are used against anyone who does not support Blockstream and the bitcoin developers who work for them is that you will be targeted in a smear campaign.

Sharp movements in the pound have worked against the Accolade float which was targeting the ASX to run off the coat tails of a stellar rally in Treasury Wine Estates.

We believe that our target group can help Indian organizations such as the International Union against Tuberculosis and Lung Disease and the Public Health Foundation of India to work towards plain packaging.

In the meantime, the United Nations should work to clarify the scope of SDG Target 12.3, in particular the material type (s) and destinations that the target encompasses and that entities should report agTarget 12.3, in particular the material type (s) and destinations that the target encompasses and that entities should report agtarget encompasses and that entities should report against.

Those long crosses to the tall target man will not work against top European teams (Manchester United is currently not one of them) without luck.

But after a 5 - 1 aggregate loss to Real Madrid in the Spanish Supercopa, Valverde got to work and built a strong side which, against all odds back in August, is on target for two trophies.

In Morrison, another case, Congress justified laws targeting violence against women by saying women worked in a national market.

And where we did achieve swings against the Tories, these were in safe Labour seats, rather than in the target marginals, in which we worked so hard.»

NOM has also promised to spend $ 1 million in the next election to protect their allies and target their own enemies to combat against the threat that LGBT advocates would work to vote out state senators who oppose such a bill (as they did with two state senators in last year's election).

«Tt is unusual for people who are targeted for people to testify because it often works against their self - interest.

In his weekly columns, Barrett targeted zinged power brokers who worked against the interests of New York's needy.

The UFT will work with its national unions, the American Federation of Teachers and the National Education Association (NEA), to fight against tax cuts that unfairly target those who need help the most including senior citizens, those who earn the least, children, the poor and the destitute.

Topics in the Q&A included the source of money for the City's planned pre-K advertising campaign, the City's target number of pre-K applicants, whether Speaker Silver thinks the proposed income tax surcharge should be pursued next year, how the pre-K selection process will work, how the City will cover the approximately $ 40 million annual gap between the estimated cost of pre-K and the amount provided in the state budget, when parents will learn whether their pre-K application has been accepted, how the City will collect data and measure success of the pre-K program, whether the existing pre-K application process will be changed, how the City will use money from the anticipated school bond issue, the mayor's reaction to a 2nd Circuit ruling that City may bar religious groups from renting after - hours space in public schools, the status on a proposed restaurant in Union Square, a tax break included in the state budget that provides millions of dollars to a Bronx condominium project, the «shop & frisk» meeting today between the Rev. Al Sharpton and Police Commissioner Bratton and a pending HPD case against a Brooklyn landlord.

In fact, fibrillarin's function appears to be similar across the entire paramyxovirus family, which includes measles and mumps, so perhaps understanding fibrillarin as a target for intervention and designing the right treatment for it could work against a broad range of viruses.

According to the scientists» findings, targeting c - FLIP with the OH14 compound works on two fronts: first by helping to deactivate the tumour's self - defense mechanism against the immune system and second to prevent its regrowth.

To make a compound work better against a specific disease target, medicinal chemists optimize the drug, tweaking its structure or physical properties to make it more effective and safer.

Experts say the work may offer a new target in the fight against colon and other types of cancers.

«This suggests that interventions targeted at working memory in people with MS may help build cognitive reserve to protect against decline in long - term memory.»

Interestingly, this system that so heavily risks damaging host DNA doesn't work so well against its intended target — APOBEC3A does not successfully eliminate the HPV virus, which remains as a chronic infection.

Another possibility that Irvine's lab is working on is developing treatments that could be used against tumors even when scientists don't know of a specific vaccine target for that type of tumor.

Those are ambitious targets, especially as TB is becoming more and more resistant to the few antibiotics that work against it.

The Illinois team, led by veterinary clinical medicine professor Dr. Matt Allender and his colleagues at the Illinois Natural History Survey, are targeting every aspect of the disease — its epidemiology, how it grows, how it is transmitted, how to treat it, and even which disinfectants work or don't work against the primary fungus associated with the disease, Ophidiomyces ophiodiicola.

The work should help provide targets for better drugs against S. pneumoniae, which is increasingly becoming resistant to existing therapies, as well as vaccines.

Previous work at CU Cancer Center shows these drugs are especially useful against lung cancers that over-express both EGFR and HER2, implying that in addition to targeting HER2 - positive lung cancers with drugs approved to treat HER2 - positive breast cancers, there may be a role for HER2 inhibitors in HER2 cancers, perhaps both breast and lung.

The identification of what happens in a rat's brain when it falls off the wagon «gives us a target against which we can work to find appropriate medications to deal with relapse,» says Alan Leshner, director of the National Institute on Drug Abuse in Bethesda, Maryland.

The new process, called Extensive Combinatorial Refinement (ExCoR), could help improve the development of drug candidates that depend to a great degree on detailed structural analysis to determine how they work against specific disease targets.

«When trying to impose any sort of change, it is important to try and empathize with our audience and to work with, rather than against, the targets of that policy.»

So a drug that targets one of these for a specific cancer, such as breast, may work against other types, such as lung.

«We are working to increase our understanding of Alzheimer's disease all the time, and there are already a number of drugs in clinical testing that are targeted against amyloid.

deCODE and its partner in this program, Roche, have initiated medicinal chemistry work on compounds they have identified as active against targets in the PDE4D pathway.

«This is another example of how our gene discovery work has led us to targets against which promising compounds have been developed by others in other indications.

Their work encompasses several strategies, including: developing FL - HCC animal models to characterize tumor - immune interactions, exploring if a mutated protein associated with FL - HCC could be targeted by immunotherapy, identifying immune checkpoints that could potentially serve as targets for immunotherapy as well as biomarkers for analyzing patients, and evaluating the effectiveness of immunotherapy strategies against FL - HCC patient samples in the lab.

Gauri's work focuses on identifying new drug targets against tuberculosis and understanding the mode of action against such targets.

Surgery, chemotherapy, and radiation work well against localized cancers, and an anti-HER2 targeted antibody — trastuzumab (Herceptin ®)-- is approved for patients with metastatic HER2 - positive esophageal cancer.

His thesis work focused on developing novel small molecule inhibitors against protein targets such as survivin and STAT3 that are essential for progression and survival of cancer.

His previous work at IDRI has included investigations into the physiology of the M.tuberculosis (Mtb) cell wall, the development of an overexpression library for high throughput target identification, and the development of target based high throughput screens for potential drug candidates against Mtb.

No doubt, you're working MORE muscles when you do planks and you're targeting important ones that stabilize your spine and protect you against back injury.

So after rebelling against my mom aka my financial advisor's wishes of me working on saving money (did I mention I made some stops at Target, Nordstrom & Old Navy?)

In both the crotch - kicking and the firebombing, Mildred's lust for justice is targeted against innocent parties — only one of those kids could have thrown the soda (and it may have been neither of them), and we later learn that the man who burned down her billboards doesn't work in the police station.

Democratic senator Mary Landrieu, a cosponsor of the «Three R's» bill, worked tirelessly, and against considerable opposition from members of both political parties, to increase the targeting of federal education dollars to low - income communities and schools in an effort to better support their school reform efforts.

Each column works and is RAGged against the target level.

We can choose to document why we made what we made in the first place, then measure how well it actually worked against that goal for the defined target audience.

In some schools, teachers met in teams to review student work against standards, using their insights to select targets for instructional improvement.

In her piece, Katherine references (but does not link to in order to avoid helping the blogger with traffic to her site, as Good e-Reader likewise will not) an article that circulated almost virally last weekend, a piece that named thirty prominent, best - selling self - published authors; while specifically targeting author Melissa Foster, who is now pursuing legal action against the blogger, the post by someone who claims to have spent two years «working undercover» at Fiverr names authors Hugh Howey, Blake Crouch, Amanda Hocking, and several others as those who purchased bulk book reviews.

As a small publisher (with authors investing in their own work to boot), I am cautious about Barnes & Noble, and outright against being carried in superstores like Target, Costco, or, god forbid, Walmart.

In the past, we've been advised to be specific about the target line, but will it work against us now?

Entering trades with open profit targets typically doesn't work for smaller traders because they end up never taking the profits until the market comes swinging back against them dramatically.

But for aspiring nomads who are working towards the goal of accumulating enough savings, they should consider this insurance which protects them against not being able to work in order to accumulate the targeted savings.