Sentences with phrase «worked with human cells»

For the new study, researchers worked with human cells and mice.

Although fragments of DNA called plasmids have been tried for the same purpose, Nagy says this is the first time a nonviral method has worked with human cells.

Although SB 247464 doesn't work with human cells, the discovery will spur the pharmaceutical industry's search for protein - mimicking drugs, says Mark Goldsmith, who studies cytokine receptors at the University of California, San Francisco.

If the approach also works with human cells, it could eventually lead to cell therapies for diseases like inherited leukodystrophies — disorders of the brain's white matter — and multiple sclerosis, as well as spinal cord injuries.

Not exact matches

Sequencing in one 18 - year - old patient found several oncogenes, and her and her family will continue to work with Human Longevity to monitor the cells.

Our home cell system is a funtional structure which has helped with building stronger relationships and works well among the yout who are highly relational at this stage of their human development, but I still feel we are missing it somewhere.

First mouse cells were turned into «totipotent» stem cells, and now early work suggests the same might have been achieved with human cells

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Recent collaborative work between UCR and Cedars - Sinai Medical Center in Los Angeles demonstrated that in animal models of human breast cancer, mice treated with 123B9 that was conjugated with paclitaxel had significantly fewer circulating cancer cells in the blood compared to mice that were not treated or even treated with paclitaxel alone.

Working with Skeletal Biologists at Southampton General Hospital, Catarina is investigating new optical techniques to monitor the development of the cells, used in new regenerative medicine approaches — in this case, to create and grow cartilage from human stem cells.

Working with human breast tissue, the new study's authors attempted to induce EMT in normal cells; they figured they would just get fibroblasts, a type of connective tissue that is important in wound healing.

«I'm working with Professor Richard Oreffo and Dr Rahul Tare from the University's Centre for Human Development, Stem Cells and Regeneration who are trying to create and grow cartilage in the lab using a patients» own (autologous) stem cells to then be implanted back into the patient if they have a cartilage defect,» she explCells and Regeneration who are trying to create and grow cartilage in the lab using a patients» own (autologous) stem cells to then be implanted back into the patient if they have a cartilage defect,» she explcells to then be implanted back into the patient if they have a cartilage defect,» she explains.

If the procedure works in humans, it would enable donated livers from humans, and possibly even from pigs, to be re-coated with a patient's own cells, reducing the likelihood of organ rejection.

The work, funded by the US National Human Genome Research Institute, aims to create human cell lines with subtly different genomes in order to test ideas about which mutations cause disease andHuman Genome Research Institute, aims to create human cell lines with subtly different genomes in order to test ideas about which mutations cause disease andhuman cell lines with subtly different genomes in order to test ideas about which mutations cause disease and how.

Since the completion of the Human Genome Project in 2003, scientists have expanded their knowledge of how living cells work with new approaches including genomics, proteomics, and systems biology.

A physician and cell biologist who won a 1972 Nobel Prize for his work describing the structure of antibodies, Edelman is now obsessed with the enigma of human consciousness — except that he does not see it as an enigma.

Working with human immune cells in the laboratory, Johns Hopkins researchers report they have identified a critical cellular «off» switch for the inflammatory immune response that contributes to lung - constricting asthma attacks.

Working with a 900 - cell organism [C. elegans] is a far cry from working with Working with a 900 - cell organism [C. elegans] is a far cry from working with working with humans.

Additionally, work in a mouse model revealed similar cells, indicating that the progenitors are conserved from mouse to human, and therefore, they must be «important cells with promising potential for cell therapy in treating liver disease,» explained Dr. Gouon - Evans.

The latter type of research, in which human cells or tissue are integrated into animals, was given the green light in the United Kingdom in October 2008, when the British House of Commons approved a bill that expanded the country's rules governing work with human embryos.

He says that his team will work to achieve all the necessary divisions in mice before trying similar manipulations with human cells.

The research team worked with human RPE cells and an experimental model of ischemic stroke.

The research team from the Department of Biochemistry and Molecular Biology headed by Professor Susanne Mandrup are publishing a paper entitled «Browning of human adipocytes requires KLF11 and reprogramming of PPAR super-enhancers» in the January 1 edition of the scientific journal Genes & Development that describes their results from working with «brite» fat cells.

Working with human breast cancer cells and mouse models of breast cancer, scientists identified a new protein that plays a key role in reprogramming cancer cells to migrate and invade other organs.

Working with human breast cancer cells and mice, scientists at The Johns Hopkins University say new experiments explain how certain cancer stem cells thrive in low oxygen conditions.

The researchers inserted the genes for the 25 subtypes into human kidney cells (an easier feat than working with real taste cells).

Hamlyn, working with Richard Schmidt of the School of Pharmacy at the University of Wales in Cardiff, exposed human fibroblast cells to six fungi strains.

In a new study the PhD students Jan Hoeber, Niclas König and Carl Trolle, working in Dr.Elena Kozlova's research group transplanted human stem cells to an avulsion injury in mice with the aim to restore a functional route for sensory information from peripheral tissues into the spinal cord.

In studies of mice injected with human cancer cells, the drug appeared to work according to plan.

While there, he worked with cell cultures derived from human fetal tissue.

Although primed, post-implantation embryonic stem cells can still turn into any type of human cell, they are more difficult to work with than the pre-implantation, naive cells.

While he has been working with federally - approved human ES lines, he notes that those lines could be considered illegal until they get vetted by the stem cell working group NIH plans to create.

They then put the dishes into special chambers called bioreactors that keep them warm and in gentle motion reminiscent of a womb, encouraging the cells to form blobs with working neurons and many other features of a full - size human brain.

But working with human smooth muscle cells isolated and grown from the healthy parts of airway tissue surrounding excised tumors, Benjamin Kalbe and his colleagues applied a large number of odor molecules and watched two of them activate the muscle cells.

But with humans, she is using iPS cells and has been working to develop the correct protocols to induce her stem cells to differentiate into different kinds of lung tissue.

Cells isolated from human umbilical cord tissue have been shown to produce molecules that help retinal neurons from the eyes of rats grow, connect and survive, according to Duke University researchers working with Janssen Research & Development, LLC.

Scientists in other countries are more likely to work with fetal cells in efforts to modify an animal's genetic makeup so that its milk contains drugs for human use.

The bill was put forth to loosen the restrictions Bush placed on human embryonic stem cell research on August 9, 2001, when he banned federal funding for work with any stem cell line created after that date.

Richard A. Insel, M.D., chief scientific officer of the Juvenile Diabetes Research Foundation, a funder of Melton's work, said the «JDRF is thrilled with this advancement toward large scale production of mature, functional human beta cells by Dr. Melton and his team.

«Our work brings us one step closer to understanding how these vital cell structures may be contributing to human ageing, with the hope of eventually specifically targeting areas of the mitochondria in an attempt to counteract the signs of ageing.»

Suspecting that the disease works differently in humans, whose brains are much bigger and more complex than those of lab animals, Brivanlou, along with research associates Albert Ruzo and Gist Croft, developed a cell - based human system for their research.

But if homologous recombination could be worked out in human (embryonic) stem cells, then cardiomyocytes with mutations in ion channels could be derived, as well as a large number of other very useful disease models of other tissues.

Because human T cells don't have as many of these brakes, our cells are a hundred times more aggressive than those of chimps when faced with drugs like TGN1412, which work by triggering the immune system.

With this ability to follow viruses in real time, the Rockefeller scientists hope to tease out how HIV recruits proteins from human cells to do its dirty work; they also plan to look more broadly at how viruses develop.

We already knew that E. coli can grip to human cells using hair - like appendages that have tiny protein hooks on their tips, but until now no one had worked out the structure of this protein, called FimH, or how it interacts with human cells.

Undeterred, advocates for the immediate use of stem cell therapy in human athletes point to successes with racehorses as the best evidence that the treatment works.

In research published in Molecular Cell, Rutgers scientists discovered that a protein (p62), which is supposed to act as an antioxidant to prevent cell damage, was not working efficiently in laboratory mice with liver and heart disease that mimicked these conditions in humCell, Rutgers scientists discovered that a protein (p62), which is supposed to act as an antioxidant to prevent cell damage, was not working efficiently in laboratory mice with liver and heart disease that mimicked these conditions in humcell damage, was not working efficiently in laboratory mice with liver and heart disease that mimicked these conditions in humans.

She ultimately chose to study leukemia patients» immune responses to bone marrow transplants, an area conducive to translational research in part because the work involves treating patients with human cells, which can be prepared at academic health centers.

Working with mouse, fly and human cells and tissue, Johns Hopkins researchers report new evidence that disruptions in the movement of cellular materials in and out of a cell's control center — the nucleus — appear to be a direct cause of brain cell death in Huntington's disease, an inherited adult neurodegenerative disorder.

Niakan and colleagues predicted from earlier work with mice and human embryonic stem cells that the protein OCT4 would be necessary for the epiblast cells to develop correctly.