Sentences with phrase «working synthetic genome»
But truly being able to make a working synthetic genome — I think it's a proof that's important.
http://discovermagazine.com/ Not exact matches
In a work published in the online version of Science magazine in May 2010, whose authors were Daniel Gibson et al., they describe the synthetic assembly of the genome needed to create the bacterium Mycoplasma mycoides.
«The idea of building whole genomes is one of the dreams and promises of synthetic biology,» says Paul Freemont, a synthetic biologist at Imperial College London, who is not involved in the work.
The current work is just 3 percent of the way toward creating an entirely synthetic yeast genome (there are 16 chromosomes in total) and will take many more years to finish.
The sequencing technology works by first chopping the genome into single - stranded DNA fragments and combining them with snippets of known synthetic DNA so that they form small circles of about 400 bases.
In May 2010, the J. Craig Venter Institute announced that its lab had built the first synthetic, self - replicating bacterial cell — that is, researchers inserted a synthetic genome, which did not exactly match the DNA sequence of any natural genome, into an existing working cell; the cell accepted the synthetic genome and reproduced.
The JCVI teams are focused on a variety of genomic research areas including continued work in synthetic biology; sampling and analysis of the world's oceans, fresh water and soils to better understand the microbes living in these environments; and new analysis on the human genome in the hopes of discovering new insights into disease prevention and treatment.
«This work sets the stage for completion of designer, synthetic genomes to address unmet needs in medicine and industry,» says Dr. Boeke, director of NYU Langone's Institute for Systems Genetics.
«This work highlights the power of combining advanced genome editing and synthetic DNA technologies to build novel cells with unique characteristics,» said Dr. Gibson, Vice President, DNA Technologies, SGI; Associate Professor, JCVI.
He described ongoing work at The J. Craig Venter Institute to produce artificial chromosomes and achieve genome transplantation as stepping stones toward the propagation of synthetic genomes.