Sentences with phrase «working version of the gene»

But mice with a working version of the gene suffered little to no damage to their gut - lining cells.

Many animals, including dogs, birds, crocodiles and amphibians, don't have a working version of the gene, or don't use it.

Without a working version of the gene encoding SWEET4c, such as in the mutant lines provided by the UniformMu resource (Don McCarty and Karen Koch at the University of Florida), sugars were not delivered to the seeds and the backpack was empty (in science jargon: empty pericarp).

Not exact matches

Normally, to achieve such a rapid evolutionary shift, a species needs to start with an alternative version of a gene already in circulation, giving natural selection more to work with, but in deer mice the new version of Agouti spread rapidly from a standing start.

Those findings prompted the two teams to work together to breed mice lacking four genes: three hoxd genes and a mouse version of hoxa - 13, which together are known to direct the development of limb ends.

Zhang worked tirelessly on this challenge, developing a highly concentrated but still - safe retrovirus derived from HIV; in essence, he removed HIV's toxic genes and replaced them with a version of ChR2.

Previous studies had shown that inherited mutations to the gene that codes for PINK1 can stop a person from making working versions of the protein.

So you're doing the work in yeast and you are looking at this particular gene construct and an ancestral version of it.

Stem cells were harvested from Nina's bone marrow and given a working version of the ADA gene, before being injected back in.

If a mother has two different versions, or alleles, of a gene, conventional genetic testing can't work out which allele she passed on to her child, because her blood contains both.

Immune cells from 4 - year - old Ashanti DeSilva are given working versions of the ADA gene to treat severe combined immunodeficiency disorder (SCID).

In two red - skinned varieties, however, they found only one version of the mutated gene; the other version worked just fine.

In 1998, working with entomologist and geneticist Kenneth Ross of the University of Georgia in Athens, Keller showed that the two groups of fire ants had distinct versions of a gene known as Gp - 9.

Gene drives might not work well enough to eradicate Zika or malaria, but an improved version of the technology may help them deliver on their promise

And now, with the UK parliament's vote in favour of three - parent babies, we are about to go a step further and actively replace damaged genes with working versions.

«Our conclusions make sense, especially in light of the work of other researchers who have shown that the human version of the FDNC5 gene has a deleterious mutation at the beginning,» Erickson said.

The researchers experimentally manipulated estrogen levels over several months in healthy women with both versions of the gene while monitoring their brain activity as they performed a working memory task.

In 2007, a research group at Children's Hospital of Philadelphia (CHOP) led by Jean Bennett began inserting a working version of the RPE65 gene into the eye by means of a harmless virus that carries the gene and «infects» the DNA of the RPE cells.

Only a year after he produced the first iPS cells from adult mouse skin cells, Yamanaka generated iPS cells from adult human skin cells, employing human versions of the same four genes that he had used in the mouse work.