Sentences with phrase «works in all different cell»

«We want to know how this system works in all different cell types and in plants that we are interested in for biofuels.»

Not exact matches

When comfort counts, this baby back pack offers lumbar and neck supports, sleeping hoods, shoulder straps that work in two different positions, and even a zippered compartment for you to put the baby's pacifier or your cell phone.

In one respect the first look is unnerving, because the chemical mechanisms that seem to drive the cancer cell astray are not different in kind from mechanisms at work in the normal celIn one respect the first look is unnerving, because the chemical mechanisms that seem to drive the cancer cell astray are not different in kind from mechanisms at work in the normal celin kind from mechanisms at work in the normal celin the normal cell.

The work, funded by the US National Human Genome Research Institute, aims to create human cell lines with subtly different genomes in order to test ideas about which mutations cause disease and how.

LKB1 is known to work through different pathways, primarily the mTORC1 and AMPK signaling pathways, in conventional T cells and other settings.

«Different types of cancer cells with different strengths and weaknesses are both present in the tumor at the same time and can work together to spread faster and more effDifferent types of cancer cells with different strengths and weaknesses are both present in the tumor at the same time and can work together to spread faster and more effdifferent strengths and weaknesses are both present in the tumor at the same time and can work together to spread faster and more efficiently.

Previous work from Dekker and colleagues had shown that points of interaction along the chromosome influence gene expression and are the reason why different cell types are organized differently in three dimensions.

Some may stem directly from how the altered digestive system works — secreting different levels of hormones, for example — or changes in nerve cells that communicate with the gut.

«The views that are expressed there are very much different from researchers in stem cell work and reproductive medicine.»

The former target, say, using gene editing techniques to inactivate HIV receptors and achieve resistance of blood cells to the virus (which Sangamo BioSciences is working on in clincial trials) is different than helping parents who both carry genes for Huntington's Disease to have a child that is free of the disease (a change to the genome that would be passed on to future generations and would likely not be very commonly needed).

Working with researchers at Johns Hopkins University in Baltimore and the University of California, San Francisco, Hynes and Rosenthal then tried adding different concentrations of Sonic hedgehog to cultured brain cells.

Professor Dan Davis and his team at the Manchester Collaborative Centre for Inflammation Research, working in collaboration with global healthcare company GSK, investigated how different types of immune cells communicate with each other — and how they kill cancerous or infected cells.

As another advantage, APC - mimetic scaffolds enabled us to tune the ratios of subpopulations of T cells with different roles in the desired immune responses, which in the future might increase their functionality,» said David Zhang, the study's second author and a Graduate Student working with Mooney.

Already, we see that cells from people with bipolar disorder are different in how often they express certain genes, how they differentiate into neurons, how they communicate, and how they respond to lithium,» says Sue O'Shea, Ph.D., the experienced U-M stem cell specialist who co-led the work.

Would we have used cell cultures we would have never found that centriole separation works differently in different developmental contexts.»

As well as looking for variations in the genome of different people's tumours, they also looked at the biological processes at work in the cells.

In their study, the team working with Zavolan exposed yeast cells to different stress conditions, measured their lifespan, protein synthesis rates and Gcn4 expression.

Nerve cells in two brain areas important to working memory use different strategies to filter out distractions.

Researchers have identified a set of DNA - binding proteins in the roots of the plant Arabidopsis thaliana that work in combination to help precursor cells selectively read different parts of the same genetic script and acquire their different fates.

One of the great challenges in biology involves finding ways to study different biological systems in cells simultaneously to understand how they work together to sustain life.

To investigate why checkpoint inhibitors so often stop working, Velculescu; Valsamo Anagnostou, M.D., Ph.D., instructor of oncology at the Johns Hopkins University School of Medicine; Kellie N. Smith, Ph.D., a cancer immunology research associate at the Johns Hopkins University School of Medicine; and their colleagues at the Bloomberg ~ Kimmel Institute for Cancer Immunotherapy studied tumors of four patients with non-small cell lung cancer and one patient with head and neck cancer who developed resistance to two different checkpoint inhibitors: a drug called nivolumab that uses an antibody called anti-PD-1, or nivolumab used alone or in combination with a second drug called ipilimumab, which uses an antibody called anti-CTLA4.

«The big surprise is that although these different types of itching have different causes, these two channels in sensory cells can work together to signal both types of itching,» said Chen, a professor of anesthesiology, of psychiatry and of developmental biology.

Chen said proving that the channels work in concert helps explain how sensory cells can process numerous types of environmental signals, including itching that results from different things.

Working with the brains of six normal children and seven autistic children ages 2 to 16, most of whom died of drowning, Courchesne has studied neurons under the microscope and even counted the number of neural cells in different tissue samples.

«Our work outlines the genetic similarities of the tissue and cells in different types of tumors and shows the strong relationships mice can have to other human cancers too.»

Generally researchers associate these cells with an immune response; however, the work by Stevens and her colleagues reveals these same cells in a different light.

«BOK is an effector of mitochondrial apoptosis that appears to work in a different way to known proteins that initiate mitchondrial cell death,» said Fabien Llambi, Research Laboratory Specialist at St. Jude and the first author of the paper.

Still, the genetic homogeneity of largely inbred mouse strains may be misleading when it comes to understanding human stem cells, cautions Peter Andrews, professor of biomedical science and co-director of the Centre for Stem Cell Biology at the University of Sheffield, U.K. «In the human, every embryonic stem cell that we're working with that comes from a different person is genetically different,» says AndrCell Biology at the University of Sheffield, U.K. «In the human, every embryonic stem cell that we're working with that comes from a different person is genetically different,» says Andrcell that we're working with that comes from a different person is genetically different,» says Andrews.

The researchers first simulated what kinds of materials and structures would work well to make lithium - sulfur cells last longer, computing how molecules in the cathode would interact with different materials.

But efforts to construct large - scale genetic circuits in mammalian cells have largely failed: For complex circuits to work, the individual components — the turning on and off of different genes — must happen consistently.

Etxebarria works in the laboratory of IK4 - Ikerlan trying out different polymers in the quest for suitable materials for manufacturing cells.

And work in fruit flies indicates that they can subtly alter their immune cells to deal with different types of microbes (ScienceNOW, 18 August 2005).

«We don't really understand how many of these chemicals work and interact at a very basic level in cells and in the body, so being able to know how they affect different people with different genetic variations is problematic at best,» she says.

As the authors also observed in previous works, some aphids showed different chromosome numbers also comparing cells belonging to a same individual «forgetting» that chromosome instability within individuals should be typical of malignant cells and not of healthy insects showing a high reproductive rate.

The organization of these tissues let different cell types work together, to enable organs in the body to perform their functions.

Varvel was working with mice in which two different types of cells are marked by fluorescent proteins.

In recent years, research at Joslin and elsewhere has shown that insulin resistance may work differently in different cell typeIn recent years, research at Joslin and elsewhere has shown that insulin resistance may work differently in different cell typein different cell types.

Tips: Göttgens suggests working with a bioinformatician to design the experiment from the outset to power the study with the right number of cells and to limit the potential influence of batch effects (in which two results differ because they were collected on different days).

The scientists discovered that Nrf2 worked in different ways to help remove either mutant LRRK2 or α - synuclein from the cells.

Working in mice, Norbury's team used several methods to deplete different types of innate immune cells — collectively known as myeloid cells — at the three checkpoints before infecting the rodents with poxvirus.

The things that we have demonstrated — such as the fact that the vertical nanowires can deliver any biological effector to any cell type in a spatially selected fashion — have drawn interest from many different people, and we have been working with stem cell institutes and others to demonstrate the unique utility of this particular platform.

Unlike «closed» systems, in which cells are enclosed in chips, Griffith's open platform would allow researchers to work directly with the cultured tissue — for example, by chemically inducing inflammation and testing how different drugs interact with the inflamed tissue.

«We compiled a list of the proteins we thought Zika and similar viruses like dengue were using to get inside of cells, and then we looked to see which of these proteins were abundantly present in the different cell types of the developing brain,» said Pollen, who did the work with Tomasz Nowakowski, PhD, and a UCSF graduate student Carmen Sandoval - Espinosa, BS, both in Kriegstein's lab.

Drugs used in chemotherapy, such as ifosfamide and doxorubicin hydrochloride, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.

I completed my PhD as a cell biology major in an engineering lab, where I established a new assay to answer questions very different from what the main part of the lab was working on.

In the present work, CuSbS2 quantum dot are prepared with different size and surface passivation process for hole transport layer of perovskite solar cells by spin - coating process.

So the idea would be to identify the enzymes these organisms use to digest lysosomal wastes, modify them a bit to help them work in the slightly different environment of the human lysosome, and then deliver them to where they need to go in our cells.

By encouraging interaction among these initiatives, researchers are learning not just how the myriad cells of the brain work individually, but how they work in concert to produce behavior — as well as how the neural circuitry of behavior is modified in response to different forms of learning.

This is why recent work in the field of cancer research has focused on picking apart the complex cellular pathways involved in the development of different cancers and identifying the roles of key proteins involved, with the goal of being able to discriminately and effectively eliminate cancerous cells from the body.

Here researchers take a different strategy to the normal approach of painstakingly tracing relationships between proteins in cells, starting at the end point of full blown disease and working backwards one step at a time.