«By decreasing ROS levels within a chronic
wound in a diabetic mouse model, my lab was able to normalize conditions and heal the wound,» Martins - Green said.
Not exact matches
Moreover, the regenerative capacity of corneal nerves following
wounding is impaired
in the corneas of
diabetic patients compared to normal B6
mouse corneas.
The SNAs were put
in the moisturizer Aquaphor and simply applied to the edges of the
wounds in diet - induced
diabetic mice.
In their experiments involving
mice with
diabetic wounds, a
wound was shown to heal stronger and thrice as fast with the application of ANGPTL4.
Remarkably, the same healing effect was produced when B cells from older obese
diabetic mice were applied to acute
wounds in similarly aged, obese
diabetic mice.
Introducing extracellular vesicles secreted from the GMSCs of healthy
mice reduced
wound healing time
in diabetic mice.
«Our plan is to apply such materials to
diabetic wounds in mouse models
in order to evaluate their efficacy.
IMAGE:
Wound healing is improved
in diabetic mice lacking TSP2.
The Joslin researchers then transplanted these modified human
diabetic cells into
wounds in mice models of diabetes that also had suppressed immune systems so that they didn't reject human cells.