Gametes lacking
the wtf genes died.
«Meiotic drive systems like
wtf genes could potentially be used to eradicate pest populations or to facilitate the spread of desirable traits in natural populations,» Zanders says.
Wtf genes are selfish genes — parasitic genes whose sole purpose is to survive and spread.
«
The wtf genes make a poison that has the potential to kill everything, including themselves.
They found that
wtf genes made two different RNA messages - a short message (which encodes the poison) and a long message (which encodes the antidote).
Zanders says the combination of their genetics experiments and imaging studies provide ample evidence that
wtf genes make both a poison and antidote.
«But the antidote was present only in the spores that inherited
the wtf gene.»
The researchers also found that wtf4 is a member of a large family of selfish genes, and that at least one other
wtf gene also causes meiotic drive, suggesting that the family proliferated due to meiotic drive.
Not exact matches
«The strategy that
wtf selfish
genes employ is to poison all the developing gametes, but then keep the antidote for themselves,» says Zanders, a Stowers assistant investigator.