Sentences with phrase «x receptor»

Physiological differences between human and rat primary hepatocytes in response to liver X receptor activation by 3 -[3 -[N -(2 - chloro -3-trifluoromethylbenzyl)- (2,2 - diphenylethyl) amino] propyloxy] phe nylacetic acid hydrochloride (GW3965).

Identification of novel NRF2 - regulated genes by ChIPSeq: influence on retinoid X receptor alpha.

Abbreviations: ASC, apoptosis - associated speck - like protein containing a caspase - recruitment domain; ATM, adipose - tissue - resident macrophage; BAT, brown adipose tissue; CCR2, CC chemokine receptor 2; CHOP, C / EBP (CCAAT / enhancer - binding protein)- homologous protein; DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; ER, endoplasmic reticulum; GPCR, G - protein - coupled receptor; HIF, hypoxia - inducible factor; IFNγ, interferon γ; IKK, inhibitor of nuclear factor κB kinase; IL, interleukin; IRS - 1, insulin receptor substrate - 1; JNK, c - Jun N - terminal kinase; LDL, low - density lipoprotein; Ldlr, LDL receptor; LXR, liver X receptor; MCP - 1, monocyte chemoattractant protein 1; miRNA, microRNA; mTOR, mammalian target of rapamycin; NAFLD, non-alcoholic fatty liver disease; NF - κB, nuclear factor κB; NLRP3, NLR (nucleotide - binding - domain - and leucine - rich - repeat - containing) family, pyrin - domain - containing 3; oxLDL, oxidized LDL; PKR, double - stranded RNA - dependent protein kinase; PPAR, peroxisome - proliferator - activated receptor; STAT6, signal transducer and activator of transcription 6; SVF, stromal vascular fraction; TLR, Toll - like receptor; TNFα, tumour necrosis factor α; UPR, unfolded protein response; WAT, white adipose tissue

Western Diet — Induced Dysbiosis in Farnesoid X Receptor Knockout Mice Causes Persistent Hepatic Inflammation after Antibiotic Treatment — Prasant K — The American Journal of Pathology

Chronic kidney disease alters lipid trafficking and inflammatory responses in macrophages: effects of liver X receptor agonism.

Retinoid X receptor gamma - deficient mice have increased skeletal muscle lipoprotein lipase activity and less weight gain when fed a high - fat diet.

Retinoid X receptor?

PPARγ appears to be part of a network of transcription factors coordinately regulating lipid uptake and cholesterol efflux in macrophages by transcriptionally regulating the scavenger receptor CD36 and the oxysterol receptor LXRα (liver X receptor α).

PPARs form heterodimers with the retinoid X receptor (RXR) and regulate transcription of their target genes and gene networks.

Infants with more methylation of a gene known as retinoid X receptor - α (RXRα), which codes for a protein involved in the development of fat cells and fat metabolism, were more likely to be obese at age 9.

Bex acts on a «master regulator» protein called retinoid X receptor (RXR), which controls a network of other cellular proteins.

OCA is the first in a new class of drugs, farnesoid X receptor (FXR) agonists, and the response of the patients to OCA shows that abnormalities in the system it targets may be critical for this condition.

Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells

This second research trend has made it clear that receptors on our cell membranes for vitamin A (called retinoid X receptors, or RXR) and receptors on our cell membranes for vitamin D (called VDR receptors) actually combine in our cells to produce an VDR / RXR form.

Not exact matches

In September, Hagerman and colleagues reported that arbaclofen, a drug that stimulates a type of GABA receptor, reduced social avoidance in people with fragile X syndrome, a genetic disorder that shares many features with autism.

Anterograde trafficking of G protein - coupled receptors: function of the C - terminal F (X) 6LL motif in export from the endoplasmic reticulum.

Nagahashi M, Takabe K, Liu R, Wang Y, Hait NC, Wang X, Allegood JC, Yamada A, Aoyagi T, Liang J, Pandak WM, Cooper P, Spiegel S, Hylemon PB, and Zhou H. Conjugated Bile Acid Activated S1P Receptor 2 Is a Key Regulator of Sphingosine Kinase 2 and Hepatic Gene Expression.

At some point in the past, random mutations created a variant of one receptor gene, located on the X chromosome, producing two different receptor types.

In contrast, among Old World (African) primates such as humans, the two different X chromosome genes duplicated so that each X chromosome now carries the genes for both receptor types, giving both males and females trichromatic color vision.

Wang D, Sun X, Sadee W. Different effects of antagonists on mu -, delta -, and kappa - opioid receptors with and without agonist pretreatment.

Jin S, Chang C, Zhang L, Liu Y, Huang X, Chen Z. Chlorogenic Acid Improves Late Diabetes Through Adiponectin Receptor Signalling Pathways in db / db Mice.