These results clearly indicate that analysis of future
xenograft experiments should take careful note of the size of the xenografts as well as how hypoxia influences CSC in the specific cell line used.
Its function as a target for cancer therapy has already been addressed in
xenograft experiments.
Not exact matches
Additional
experiments also showed that TiY can suppress the tumor growth in mice
xenograft model.
In these
experiments, Berger and colleagues show that somatic PREX2 mutations identified through whole - genome sequencing of human melanoma can contribute to enhanced lethality of tumor
xenografts in nude mice (Figure 3B, S6B, and S6C; Berger et al., 2012).
In a series of lab
experiments with cell lines, human
xenograft tumors in mice and primary human prostate cancer samples, the researchers demonstrated that miR - 34a inhibits prostate cancer stem cells by suppressing CD44.