Sentences with phrase «year changes decreased»

After that, the 10 - year changes decreased consistently, turning from positive to negative.

Not exact matches

This change resulted in a decrease in previously reported net sales and an increase in operating income for total year 2017 of $ 1 million and $ 42 million, respectively, in the Electronics and Energy segment, offset by a corresponding increase in net sales and decrease in operating income within Corporate and Unallocated.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Under the proposed changes announced by the Minister of Finance, EI premium rates are not allowed to increase / decrease by more than 10 % per $ 100 of insurable earnings from any year to the next.

Median home price change expectations decreased from 3.3 % in August to 3.1 %, remaining within the narrow 3.0 % to 3.3 % band observed over the last 12 months, and staying well below the readings in the previous two years.

Operating expenses for the year were $ 72.2 billion, a decrease of $ 4.7 billion, or 6.1 percent, compared to the prior year, although this net reduction was largely attributable to changes in actuarially determined expenses outside of management's control.

However, he said the MLS home price index composite benchmark, which strips out the impact of changes in the mix of home sales, was down 5.2 % compared with a year ago and the number of new listings in April had plunged to 16,273, a 24.6 % decrease from the 21,571 listings seen last year at the same time.

Select from 1, 3, 5, 7, or 10 year periods during which the interest rate remains unchanged, followed by 1 - year periods in which the interest rate may increase or decrease on an annual basis resulting in a change in your monthly payment amount

All industries included in last year's study saw a change in engagement rate, but not necessarily a decrease.

Examples of these risks, uncertainties and other factors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.

The frequency of extreme events has either not changed or has decreased in the 150 years that CO2 levels have increased from 270 to 390 ppm.

But I would say that my identity has changed: I see myself as a son of God, not as a gay man any more... The sexual temptations are still there, but my desire to be in a relationship with a guy has decreased significantly over the years.»

Yesterday brought some good news out of the UN climate change conference in Paris: Carbon emissions stalled — and possibly even decreased — this year, according to a new study.

Most of us did improve, of course, but the professor who proctored our exam said that over the years, the test has not changed, but the scores have steadily decreased.

These changes, along with the low scoring output in the 2014 Pro Bowl, caused oddsmakers to decrease the total by 20.5 - points (from 89 to 68.5) for last year's Pro Bowl.

As a result of rule changes, equipment standards, better conditioning of the neck, and improved on - field medical care, there has been a dramatic decrease over the past 20 years in the most serious head injuries.

One of the changes administrators made in the new budget was to decrease funding for capital projects by about 26 percent to around $ 2.2 million from $ 2.8 million from previous year, documents show.

To accommodate evolving parenting styles with the goal of decreasing the social isolation of parents, museums, libraries, swimming pools, and even vacation destinations have changed during the last ten years.

Another important change envisioned by Fontana is for senators to have their term decreased from 8 to 4 years.

But this accounting change will decrease fiscal year 2019 SOF spending by $ 1.5 billion.

In adopting that change, however, Cuomo and the Legislature added a «transition adjustment» sharply limiting how much each hospital's grant could increase or decrease in a given year.

The decrease is likely also driven by the changed political calculus for both unions and charter groups after most of Gov. Andrew Cuomo's sweeping education reform proposals failed during last year's legislative session.

The study saw changes that included an overall decrease in cold events, a higher probability to have a year without a cold spell, and an increase in the annual number of wet days.

«The prevalence of lifetime and past - year suicidal ideation among male military personnel did not change over time; however, female military personnel had a significant decrease in lifetime suicidal ideation,» write the authors.

Yesterday's study suggests that total glacier volume across all the investigated basins will decrease by about 43 percent by the year 2100, even if the world takes serious steps to mitigate climate change.

Changes in forest structure and species composition alone decreased water yield by as much as 18 percent in a given year since the 1970s after accounting for climate.»

Results demonstrate important changes in students» drinking during the calendar year, including expected large increases during the month of a one - day festival, large decreases over the summer, and resumption of relatively high quantities upon return to school.

«While we've seen a decrease over the years in motor vehicle fatalities involving people under the influence, the nature of those crashes is changing,» said study author Fernando Wilson, PhD, associate professor at the University of Nebraska Medical Center.

«If climate change caused this year's water flow decreases, which I think it did, and then its impact [on rivers] will be a long term.

Changes in farming practices over the last 50 years have resulted in decreased agro-diversity which, in turn, has resulted in decreased dietary diversity.

I guess I am surprised that with better understanding of the importance of water vapor feedback, sulfate aerosols, black carbon aerosols, more rapid than expected declines in sea ice and attendant decreases in albedo, effects of the deposition of soot and dust on snow and ice decreasing albedo, and a recognition of the importance of GHGs that were probably not considered 30 years ago, that the sensitivity has changed so little over time.

The global mean temperature rise of less than 1 degree C in the past century does not seem like much, but it is associated with a winter temperature rise of 3 to 4 degrees C over most of the Arctic in the past 20 years, unprecedented loss of ice from all the tropical glaciers, a decrease of 15 to 20 % in late summer sea ice extent, rising sealevel, and a host of other measured signs of anomalous and rapid climate change.

has decreased in winter, but no significant change in annual mean precipitation potentially because of very slight increases in spring and fall precipitation; precipitation is projected to increase across Montana, primarily in spring; slight decrease in summer precipitation; variability of precipitation year - to - year projected to increase

Over six years, the researchers found that increases in the amount of fat and decreases in fat density were linked with changes in the risk for heart disease.

If making simple changes in her diet helped her drop 20 lbs., disappeared a pre-diabetic condition and allergies, gained energy, decreased fibromyalgia symptoms — what will happen if she sticks with it for a year?

I note that you mentioned that gaining weight for you was the «nail in the coffin» for your acne and overall health and have been working on gaining weight to aid in hormone balance (plus my husband and I have been trying to conceive since married two years ago without success thus far — doctors tell us everything in working order but recommend I gain some weight / decrease stress which led to the job change etc.) but find that it's rather two steps forward one step back when going paleo: I gain a couple lbs and then lose it.

I am living in Sweden and tried to talk to my doctor about hormons... I get energy crash in beggining of menopause and tried to menage it with progesteron (some intervals) and stress management, like life style changes, vitamins, minerals, nutritions, exercizes, etc. but I feel after 2 years (now I am 53) that energy still very low, and I feel dizzyness, brain fog, decrease memory and I get joints pain in arms mostly (menopausal arthritis?).

Intriguingly enough, it has been shown that three months of aerobic exercise decreases ET - 1 concentrations in both young and elderly subjects.6 Moreover, 45 minutes of moderate - intensity treadmill running in 13 men and women 70 years of age completely restored insulin - induced increases in protein synthesis.6 Those changes were associated with a drop in ET - 1.

by simply changing my diet, resolved a hormone and diet - driven issue I have had since I was 15 years old, no longer feel tired all the time, am seeing a huge improvement in my thyroid symptoms and am unbelievably getting to decrease my thyroid medication.

Only in a prospective study from Lopez - Garcia et al., 69 who studied the effect of caffeine on long - term weight change in a cohort, it was found that people who increased the caffeine consumption over 12 years gained less weight than those who decreased the caffeine consumption.

Mean 5 - year change was approximately 31 g sugar from sweet food / beverages per day in the decrease group, − 0.7 g in the stable intake group and 29 g in the increase group.

In a June 2011 survey done by the female favorite magazine's website, traditional fantasies showed a steady decrease from the same survey a year before, but one surprising change was on the rise: The trans fantasy.

No state has seen a more dramatic decrease in teacher salary rankings in the past 10 years, and some of the other changes in public education are unprecedented.

The only significant change since 2013, the year de Blasio was elected, was a 7 - point decrease in the proportion of fourth graders considered proficient in math.»

Other indicators of positive systemic change are: 29 % enrollment increase compared to five years ago; increase in graduation rate from 84.1 % (2012 accountability report) to 97.5 % (2015 accountability report); increase in attendance rate from 93.3 % (2012 accountability report) to 95.0 % (2015 accountability report); and a 22 % decrease in discipline referrals from 2011 - 2012 to 2014 - 2015.

The talk around the water cooler has changed over the years, but school administrators keep returning to the same issues - how do we comply with the ADA; how do we address increasing enrollment and decreasing dollars; should we contract services out or keep them in - house; how can we keep our students, faculty and facilities safe and secure; where does technology fit into our educational goals.

Analyses revealed that the following observations changed by at least 10 % from Year 2 to Year 1: increase in whole - group instruction, decrease in small - group instruction, increase in coaching in word recognition strategies during reading, decrease in asking of lower - level questions, increase in asking of higher - level questions, increase in comprehension skill instruction, decrease in active pupil responding, increase in passive pupil responding.

Districts wouldn't even have to foot the bill; I did some back - of - the - envelope calculations based on the 2011 Annual Report and found that with the savings picked up by the decreased recruitment pool and corps size (going with Wendy Kopp's «applicant pool fell in half» and your 3000 number, respectively), TFA could afford to pay each first - year CM a ~ $ 23,000 stipend (modulo one - time costs related to changing the structure of the organization so dramatically).

That year also saw minor changes to the cabin that improved comfort, the addition of a catalytic converter that decreased emissions and the replacement of the 240 GD with the 250 GD.

Due to algorithm changes on Facebook, social shares have decreased almost 50 percent in the past year.