Sentences with phrase «year duration of the study»

Over the 3 - year duration of the study, some of the participants who hadn't been diagnosed with Huntington's disease at the beginning of the study have now developed symptoms of the disease.

Even the people predicted to be far from onset had specific areas of brain change during the 3 - year duration of the study.

Again, our model explained significant variance and was a good fit to the data in CARDIA for year 15 blood pressure, as well as for increases in blood pressure over the 15 - year duration of the study.

Not exact matches

In tracking all the comings and goings to the S&P 500 for the last 50 years, the study shows that the duration companies spend on the list fluctuates in cycles mirroring the overall state of the economy and disruption from new technologies, including biotech breakthroughs, social media, and cloud computing.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

In the Vanguard study the 5.5 year duration of the fund meant that for a 1 % increase in yields you would expect the price to fall by roughly 5.5 %.

A large component of the project comprised of a breastfeeding peer support program which consisted of prenatal visits, hospital visits, home visits and phone calls with anticipatory breastfeeding guidance for up to an infants» first year of life to ascertain that woman in the study will breastfeed for longer durations to establish a link between DHA and neurological development.

The study concluded, «Higher lactation intensity and longer duration were independently associated with lower two - year incidences of Diabetes Mellitus (DM) after gestational diabetes mellitus (GDM) pregnancy.

Of note, our models may underestimate the true maternal costs of suboptimal breastfeeding; we modeled the effects of lactation on only five maternal health conditions despite data linking lactation with other maternal health outcomes.46 In addition, women in our model could not develop type 2 diabetes mellitus, hypertension, or MI before age 35 years, although these conditions are becoming increasingly prevalent among young adults.47 Although some studies have found an association between lactation and rates of postmenopausal diabetes22, 23 and cardiovascular disease, 10 we conservatively limited the duration of lactation's effect on both diabetes and MOf note, our models may underestimate the true maternal costs of suboptimal breastfeeding; we modeled the effects of lactation on only five maternal health conditions despite data linking lactation with other maternal health outcomes.46 In addition, women in our model could not develop type 2 diabetes mellitus, hypertension, or MI before age 35 years, although these conditions are becoming increasingly prevalent among young adults.47 Although some studies have found an association between lactation and rates of postmenopausal diabetes22, 23 and cardiovascular disease, 10 we conservatively limited the duration of lactation's effect on both diabetes and Mof suboptimal breastfeeding; we modeled the effects of lactation on only five maternal health conditions despite data linking lactation with other maternal health outcomes.46 In addition, women in our model could not develop type 2 diabetes mellitus, hypertension, or MI before age 35 years, although these conditions are becoming increasingly prevalent among young adults.47 Although some studies have found an association between lactation and rates of postmenopausal diabetes22, 23 and cardiovascular disease, 10 we conservatively limited the duration of lactation's effect on both diabetes and Mof lactation on only five maternal health conditions despite data linking lactation with other maternal health outcomes.46 In addition, women in our model could not develop type 2 diabetes mellitus, hypertension, or MI before age 35 years, although these conditions are becoming increasingly prevalent among young adults.47 Although some studies have found an association between lactation and rates of postmenopausal diabetes22, 23 and cardiovascular disease, 10 we conservatively limited the duration of lactation's effect on both diabetes and Mof postmenopausal diabetes22, 23 and cardiovascular disease, 10 we conservatively limited the duration of lactation's effect on both diabetes and Mof lactation's effect on both diabetes and MI.

Moreover, data for exposures in almost all studies were based only on maternal recall, sometimes some years after the exposures, although studies have shown that mothers remember breastfeeding durations many years after breastfeeding has stopped.55 - 57 Furthermore, research shows that mothers of sick children sometimes remember early exposures of their children in greater detail compared with mothers of healthy children, especially when the exposures are publicly perceived to be associated with the outcome studied.

The aims of our study were 2-fold: (1) to examine relationships of breastfeeding duration and exclusivity with child cognition at ages 3 and 7 years and (2) to evaluate the extent to which maternal fish intake during lactation modifies associations of infant feeding with later cognition.

One study that dealt specifically with babies nursed longer than a year showed a significant link between the duration of nursing and mothers» and teachers» ratings of social adjustment in 6 - 8 year old children.

Additionally, the U.S. Nurses» Health Study found only women with a lifetime duration of breastfeeding of 2 years or more had a significantly lower risk of coronary heart disease than those who never breastfed.

In a study of a homogeneous (similar age, SES and education) population where mothers had a favourable environment and most infants were breastfed, the duration of breastfeeding clearly made a difference in cognitive development at 13 months and five years.

Long - term (≥ 18 years) maternal recall of breastfeeding duration has been used in studies of the association of infant feeding with adult obesity (32), adult vascular function (10), and both child -(33, 34) and adult -(8) onset diabetes.

inclusion criteria: women aged 17 - 40 years, married, in their third trimester of pregnancy, and intending to reside in the study area for the duration of the study

He has argued that in view of the global race for development, a Ghanaian president needs time to implement his programmes and also plan the economy At International Society for African Philosophy and Studies (ISAPS) conference on the theme «Democracy Justice and Development in Africa: 50 Years after Independence», former president Kufuor criticized the framers of the Constitution for failing to undertake adequate research before deciding on the duration for Presidency.

At International Society for African Philosophy and Studies (ISAPS) conference on the theme «Democracy Justice and Development in Africa: 50 Years after Independence», Joy FM quotes former president Kufuor as criticizing the framers of the Constitution for failing to undertake adequate research before deciding on the duration for Presidency.

The application of 10 - year Framingham Risk Scores should be interpreted with caution as the duration of the BJN study was weeks not years and the number of participants was around 100, not reaching the scale of the Framingham studies.

The intensification of winter storm activity in Alaska and Northwestern Canada started close to 300 years ago and is unprecedented in magnitude and duration over the past millennium, according to a new study from Dartmouth College.

However, Schellenberg and von Scheve believe that the steady increase in duration and decrease in tempo that they found in their study doesn't support the idea of growing difficulties fully because it would mean our problems have increased steadily over the last fifty years.

On average, the disks studied by Spitzer turn out to be 100 million years old, one hundred times the duration of planet formation implied by the Cohen - Kuhi Tau / 4 results.

Another study of 4,175 individuals between 11 and 17 years of age is the first to document reciprocal effects for major depression and short sleep duration among adolescents using prospective data.

New research indicates that hormonal intrauterine devices (IUDs) and contraceptive implants remain highly effective one year beyond their approved duration of use, according to a study at Washington University School of Medicine in St. Louis.

New research indicates that hormonal IUDs, pictured here, and contraceptive implants remain highly effective one year beyond their approved duration of use, according to a study at Washington University School of Medicine.

«The duration of support is outstanding,» said Dr. George Mychaliska, a pediatric and fetal surgeon at C.S. Mott Children's Hospital, who has spent the past 10 years researching similar systems, and was not involved in this study.

Webster is now studying the duration of the hurricane season each year, from the first tropical cyclone to the last.

«For various periods over the last 60 years, we have been able to combine important processes: atmospheric variability, such as the North Atlantic Oscillation, water and air temperatures, the occurrence of fresh surface water, and the duration of convection,» explains Dr. Marilena Oltmanns from GEOMAR, lead author of the study.

The study included 9,359 JIA patients with a mean age of 12 years and a mean disease duration of 4.5 years, recorded in the German national paediatric rheumatologic database (NPRD) in 2012 and 2013.

Encouraging — but not requiring — NIH institutes and programs to support doctoral study for a maximum duration of 5 years, with extra time permitted in special circumstances

The study group consisted of 96 healthy adults between the ages of 18 and 50 years with sleep duration of 6.5 hours or more.

«Conditions were so warm that they affected the flowering time and flowering duration of species, forming communities in 2015 that simply did not exist in the other years of our study.»

Study Selection Inclusion criteria consisted of clinical trials using oral isotretinoin, doses of 40 mg / d or more, duration of at least 4 weeks, patients aged 9 to 35 years with acne vulgaris, and 10 or more participants.

Most of the patients had a long CFS disease duration, also with a stable or worsening clinical course the last year before study entry.

We also performed subgroup meta - analyses by type of prevention (primary v secondary: in this study, trials involving healthy populations or patients with any specific disease except for cardiovascular disease were classified as primary prevention trials, and trials involving patients with cardiovascular disease were classified as secondary prevention trials), type of supplement by quality and dose (each supplement, vitamins only, antioxidants only, or antioxidants excluding vitamins), type of outcome (cardiovascular death, angina, fatal or non-fatal myocardial infarction, stroke, or transient ischaemic attack), type of outcome in each supplement, type of study design (randomised, double blind, placebo controlled trial v open label, randomised controlled trial), methodological quality (high v low), duration of treatment (< 5 years v ≥ 5 years), funding source (pharmaceutical industry v independent organisation), provider of supplements (pharmaceutical industry v not pharmaceutical industry), type of control (placebo v no placebo), number of participants (≥ 10000 v < 10000), and supplements given singly or in combination with other vitamin or antioxidant supplements by quality.

The longitudinal study analyzed the association of aspirin, with varied doses and duration of use, on overall mortality risks and mortality risks from cancer over a nearly 32 - year period.

These programs provide opportunities for visiting professionals from industry or universities to participate in established research studies at Ames Laboratory, usually for periods of six months to one year in duration.

We conducted a 15 - month parallel - group randomized study of adults with ALS, diagnosed according to the El Escorial revised diagnostic criteria (47), with a disease duration of < 5 years.

In a six year study, 12,059 volunteers had their lifestyle and diet analyzed at the start of the study, throughout its duration and also at the finish of the study.

Out of the 27 individuals that were assessed in this study, 18 had type 2 diabetes with a duration of the condition for less than 15 years, all within the range group of 25 to 65 years and a body mass index marking them as obese.

Although it is often suggested that children with epilepsy who are benefiting from ketogenic dietary therapy continue this for at least two years, duration of treatment could be shorter in patients with infantile spasms who become seizure - free; one study reported no adverse effect on seizure outcomes and less risk of growth disturbances when treatment was tapered down after 8 months (15).

Of the 17 women, aged 33 - 58 years, who participated in the study, 86 % practiced yoga at home throughout the entire four - week duration of the studOf the 17 women, aged 33 - 58 years, who participated in the study, 86 % practiced yoga at home throughout the entire four - week duration of the studof the study.

The study covered marriages of 6 - 7 years duration and those that originated from online dating websites were less likely to end in divorce than those of any other origin.

For instance, if you are planning to study Masters, then of course you do need to have at least a four years graduate degree in many cases, while if you like to study for shorter duration, certification or diploma courses may be better.

Over the duration of the last academic year I have been studying this theory, using learning observations, meetings with teachers, student voice, book looks and learning walks (supportive strolls) as sources of information from which I could hopefully draw some conclusions.

During these years, we have established such a high reputation that led to 90 % of customers returning to us, many of them using our services in duration of the whole study period.

Each student works with experts / critical friends during field - based learning experiences, and have the added benefit of the support of a mentor throughout the duration of their two - year study.

Almost all rabies vaccinations on the market for dogs today have been shown to last at least three years via duration of immunity studies.

Once this booster is given studies show the duration of immunity anywhere from 8 - 15 years and most likely lifetime.

The duration of immunity for rabies vaccine, canine distemper vaccine, canine parvovirus vaccine, feline panleukopenia vaccine, feline rhinotracheitis, feline calicivirus, have all been shown to last a minimum of 7 years by serology (measuring blood antibody levels) for rabies and challenge studies for all the rest.