Sentences with phrase «year timeframe at»

John, Ove also came out with the 150 year timeframe at the Brisbane meeting, which to those of us in the audience with a true geological background was just another example of the lack of understanding of a marine biologist for real earth history as you rightly point out.

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

To use a simple example, if Company A grows its cash flows at 6 % for 30 years and Company B grows at 3 % over the same timeframe, Company A is worth nearly 65 % more than Company B today assuming that both companies converge to a 3 % growth rate thereafter1.

Before you provide the best set of criteria (the one that beats the spread at 59.2 %), you divide your (curiously - chosen) 11 - year timeframe into two parts: 2005 - 2009 and 2010 - present.

When I think of the volume of players... It makes sense that a rebuild will have to take 2 years at the quickest timeframe the board feel it can be done.

And of course, exceeding the 1.5 °C threshold for even an entire year would not mean that global temperatures had in fact risen to that point, never (at least within our lifetime) to drop back below it as it's too short of a timeframe to make that determination.

Specifically, the study ostensibly showed that HIV - negative people had an 80 percent Hodgkin lymphoma survival rate five years after diagnosis, but HIV - positive people survived at a rate of only 66 percent over the same timeframe.

Stein and his colleagues looked at the seismic records and more than 2,000 years of written records in northern China and found that, during that timeframe, no magnitude - 7 or greater quake ever hit at the same place on a fault more than once.

The researchers looked at the cost effectiveness of the DIMM clinic from three perspectives (clinic, health system and payer) at three different timeframes (six months, three years and 10 years).

Over a 100 - year timeframe, methane is about 34 times as potent at trapping heat than carbon dioxide, and over 20 years, it's 86 times more potent.

Deep cuts in emissions will require signals that the CO2 price at $ 30 or above is here to stay and that the caps on emissions will be imposed and become ever stricter each year over decadal timeframes.

I've been working out consistently at least 3x week on your program (push / pull / legs) for about a year, and while I have clearly put on a significant amount of muscle (visibly evident), my weight really hasn't budged at all in that timeframe.

It's also likely these dates were established at the beginning of the school year for all seasonal benchmarking timeframes, and, consequently, the window will automatically be open in the FAST system on the pre-determined start date.

Given the compressed timeframe in which the dissolution of the SRC must take place in order for the District to regain local control by the beginning of the 2018 - 2019 school year and the difficulty the District would likely face getting legislative approval from Harrisburg to change its charter to allow an elected school board in the next few weeks, Education Voters of PA supports mayoral control of the school board at this time.

Each of the plan's seven guiding strategies is broken down across three timeframes - awareness, transition and implementation - with tasks and target dates aimed at full implementation by the start of the 2014 - 15 school year.

At a minimum, due to the timeframes required by this Order and reported on to the EEOC, all managers should participate in DOT reasonable accommodation policy training every two years, provided by DOCR or OA CR offices.

The Cadillac CTS coupe, which GM unveiled in near - production form at the North American International Auto Show in Detroit earlier this year, will follow the SRX to Cadillac dealers in the August timeframe, Howell tells Ward's.

BlackBerry previously vowed to release Android 8.0 (Oreo) update for the phone at some point this year but the company has yet to attach a more specific timeframe to that promise.

Instead of the measured, slow changes in allocations that we might consider, the writer's timeframe was usually one month and one year at the longest.

In the case of a Chapter 13 Bankruptcy, a borrower may qualify for an FHA loan if at least one year of the pay - out period has been completed and the applicant can show a satisfactory payment history during that one year timeframe.

The core of Bengen's findings was that no matter what day you retired on during the studied timeframe of 75 years (starting in 1926), if you withdrew 4 % of the starting balance at the beginning of a 30 - year retirement with a 50 % stocks and a 50 % bond portfolio, you would not run out of money before the end of the period.

Early Retirement Now's extensive series looks at timeframes up to 60 years.

When you consider that stocks were down more than 50 % at one point in that timeframe, 5 % per year looks really good.

While some structured products have a much shorter timeframe, for example, 1 to 2 years, capital may be at risk rather than protected.

Lastly, while we had originally expected this game to launch late in our fiscal year 2019, we're now looking at a new timeframe that we will announce in the future.

Deep cuts in emissions will require signals that the CO2 price at $ 30 or above is here to stay and that the caps on emissions will be imposed and become ever stricter each year over decadal timeframes.

This may be, but it at least demonstrates that the GCMs are inadequate at 24 - year timeframes.

On multi-decadal timeframes, GH gas forcing and the PDO / AMO combination have been having fairly even in their relative forcing over the past century, but the GH gas forcing is growing so large that it now dominating these longer - term natural variations... so the kicker is that the rapidly increasing GH gases, now at their highest levels in millions of years, are very likely influencing the nature of ENSO, PDO, AMO, and other formerly «natural» cycles.

At the risk of oversimplifying, the effects of groundwater storage can be differentiated between shallow - aquifer effects that modulate global sea level on year to year and decade to decade timeframes, versus deep aquifer effects that modulate sea level trends over centuries and millennia.

The PTC is slated to phase - out over the next few years, and currently stands at $ 24 / MWh, but because of how the tax equity market works, and the 10 - year timeframe to receive the PTC, its «full» value is much less than its face value.

4) If the error bars or margin of error is within small acceptable limits appropriate for most scientific fields, declare that the models are at least trustworthy for 30 - 50 year timeframe.

Since stabilization is unlikely to be achieved before 2050, that implies that we should be looking at timeframes of 100 years or even longer.

One of the nice things about small Japanese cars in the late 1970's / early 80's timeframe, or the «Smart Car» that was put on display at the Detroit auto show in recent years, is they do a better job than domestically - produced small cars in developing a certain, unexplainable cachet with young, hip and environmentally aware consumers.

In essence, climate variability looks at changes that occur within smaller timeframes, such as a month, a season or a year, and climate change considers changes that occur over a longer period of time, typically over decades or longer.

For example, if your goal is to secure your children's upbringing, this timeframe typically covers a finite period of, at most, 20 - 25 years.

If you are 19 years or older, and you are involved in some combination of at least three avoidable traffic accidents or traffic violations within a two year timeframe, the Fairview Oregon DMV will likely restrict or suspend your license for a minimum of one month.

If you are 19 years or older, and you are involved in some combination of at least three avoidable traffic accidents or traffic violations within a two year timeframe, the Coos Bay Oregon DMV will likely restrict or suspend your license for a minimum of one month.

If you are 19 years or older, and you are involved in some combination of at least three avoidable traffic accidents or traffic violations within a two year timeframe, the Coquille Oregon DMV will likely restrict or suspend your license for a minimum of one month.

If you are 19 years or older, and you are involved in some combination of at least three avoidable traffic accidents or traffic violations within a two year timeframe, the Florence Oregon DMV will likely restrict or suspend your license for a minimum of one month.

If you are 19 years or older, and you are involved in some combination of at least three avoidable traffic accidents or traffic violations within a two year timeframe, the Medford Oregon DMV will likely restrict or suspend your license for a minimum of one month.

If you are 19 years or older, and you are involved in some combination of at least three avoidable traffic accidents or traffic violations within a two year timeframe, the Ontario Oregon DMV will likely restrict or suspend your license for a minimum of one month.

If you are 19 years or older, and you are involved in some combination of at least three avoidable traffic accidents or traffic violations within a two year timeframe, the Nyssa Oregon DMV will likely restrict or suspend your license for a minimum of one month.

If you are 19 years or older, and you are involved in some combination of at least three avoidable traffic accidents or traffic violations within a two year timeframe, the Winston Oregon DMV will likely restrict or suspend your license for a minimum of one month.

If you are 19 years or older, and you are involved in some combination of at least three avoidable traffic accidents or traffic violations within a two year timeframe, the Bandon Oregon DMV will likely restrict or suspend your license for a minimum of one month.

If you are 19 years or older, and you are involved in some combination of at least three avoidable traffic accidents or traffic violations within a two year timeframe, the North Bend Oregon DMV will likely restrict or suspend your license for a minimum of one month.

If you are 19 years or older, and you are involved in some combination of at least three avoidable traffic accidents or traffic violations within a two year timeframe, the Mount Angel Oregon DMV will likely restrict or suspend your license for a minimum of one month.

If you are 19 years or older, and you are involved in some combination of at least three avoidable traffic accidents or traffic violations within a two year timeframe, the Monmouth Oregon DMV will likely restrict or suspend your license for a minimum of one month.

If you are 19 years or older, and you are involved in some combination of at least three avoidable traffic accidents or traffic violations within a two year timeframe, the Lincoln City Oregon DMV will likely restrict or suspend your license for a minimum of one month.

If you are 19 years or older, and you are involved in some combination of at least three avoidable traffic accidents or traffic violations within a two year timeframe, the Eugene Oregon DMV will likely restrict or suspend your license for a minimum of one month.

If you are 19 years or older, and you are involved in some combination of at least three avoidable traffic accidents or traffic violations within a two year timeframe, the Philomath Oregon DMV will likely restrict or suspend your license for a minimum of one month.