In his own tenure as supe, for instance, he oversaw a program that reduced special ed costs even as the share of special ed students achieving proficiency in a three -
year trial program increased by 26 percent in English and 22 percent in math.
The rules will establish a two -
year trial program to recoup funds from individuals by withholding income - tax refunds.
Not exact matches
The e-commerce giant, which started testing the
program in India two
years ago, plans to expand the
trials throughout the rest of the US next
year.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full
year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other
programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (t
programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance
Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (t
Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical
trials involving investigational compounds; Gilead's ability to initiate clinical
trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory
programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (t
programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase
program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
Wal - Mart's free shipping offer will be in addition to the recently launched 30 - day free
trial of ShippingPass, its unlimited 2 - day shipping
program, which costs $ 49 per
year.
Social Capital kicked off a
trial of Carroll's model last
year with a referral
program of sorts — the fund asked other venture capital firms to direct promising early - stage companies to apply through the system.
Although Anavex Life Sciences» Alzheimer's disease
program should offer up plenty of data to digest this
year, its research
program is very early stage, and the company's balance sheet is worrisome enough for me to avoid it until placebo - controlled
trial results are available.
Interestingly, we had one aspect of your hypothetical answer here when our immigration department set up a community pilot
program to
trial the concept of advocating organisations sponsoring refugees to come here and the support them for a few
years.
The new arrangement was designed as an experimental
trial run whose consequences were to be evaluated after no fewer than nine and no more than 12
years, at which point the legislature had to decide whether to continue, alter or abolish the
program.
Despite vandalism in one of the five multilocation field
trials in August this
year, data are being readied for submission to government regulators who will review Golden Rice against international standards for biosafety, according to Antonio Alfonso, coordinator of the biotechnology
program of the Philippine Department of Agriculture (DA) and leader of the Golden Rice project at the DA - Philippine Rice Research Institute (DA - PhilRice).
The philosophy for the group that has sent multiple swimmers to Olympic
Trials and on to swim for top college swimming
programs for the past 25
years is, «Character is what you do when no one is looking.»
Educare is currently conducting a long - term randomized controlled
trial that, when it is completed in the next few
years, may be able to conclusively demonstrate the
program's effectiveness.
EAT Breakfast, This breakfast
program was implemented as a
trial run about two and a half
years ago.
In a randomized
trial, a home visiting
program reduced physical and psychological abuse after 1
year of participation and had the greatest impact on first - time and psychologically vulnerable mothers after 2
years of participation.
Studies of the Nurse Family Partnership model followed children to 6
years and found significant
program effects on language and cognitive functioning as well as fewer behaviour problems in a randomized controlled
trial study.24 In addition, more recent evaluations of Healthy Families America have shown small, but favourable effects on young children's development.25, 26
The
program of prenatal and infancy home visiting by nurses described above produced treatment - control differences in 15 -
year - olds» arrests and reductions in arrests and convictions among 19 -
year - old females.32, 33 In a subsequent
trial with a large sample of urban African - Americans the
program produced treatment impacts on 12 -
year - olds» use of substances and internalizing disorders.34
A series of randomized control
trials of a nurse home visitation
program show a range of positive effects on maternal health, including decreases in prenatal cigarette smoking, fewer hypertensive disorders in pregnancy, and fewer closely spaced subsequent pregnancies., A randomized control study of another
program that works with a particularly high - risk population found that participant mothers showed significantly lower depressive symptoms than those in the control group and were less likely to report feeling stressed a
year after participation.
A
trial court in Rensselaer County has thrown out a union challenge to a pair of
programs started by Cuomo — the Empire and Excelsior Service fellowships — that recruits young professionals and those just getting out of school, to work at high level jobs in state government for two
year periods.
While Kaloyeros has denied any wrongdoing as he seeks to clear his name at
trial next
year, school officials have sought a substantial bailout from the state worth tens of millions of dollars to shore up various academic, research and construction
programs there.
Among those who face
trial next
year, a former top aide to the governor, and the former head of the State University of New York's nanotech science
program.
Another corruption
trial scheduled to begin this
year involves Alain Kaloyeros, who was president of SUNY Polytechnic Institute and is accused of rigging bids for projects part of the «Buffalo Billion,» one of Cuomo's top economic development
programs.
The company started a new education
program, with Lisa Percoco making $ 90,000 a
year for what was labeled during the
trial as a «low - show» position that sought to educate grade school children about the benefits of the power industry.
Nine people have pleaded guilty or been indicted in connection with alleged bid rigging and other corruption charges involving some of Governor Cuomo's economic development
programs, and they face
trial later this
year.
A small clinical
trial earlier this
year found that the
program helps teens with autism improve their sexual knowledge, build confidence and prevent inappropriate behaviors.
The FDA already has a 6 -
year - old
program called the Critical Path Initiative that, according to its Web site, funds a number of research projects on topics such as clinical
trial design.
In a randomized controlled clinical
trial, scientists from Joslin Diabetes Center and Brigham and Women's Hospital found that patients treated with a form of bariatric surgery known as Roux - en - Y gastric bypass did significantly better, after three
years, than patients provided with an intensive diabetes and weight management
program.
In 5
years as inaugural director of USC's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, Pera built a stem cell
program spanning basic research to clinical
trials.
Nelson Michael of the U.S. Military HIV Research
Program, which helped run the
trial, is more optimistic: «We've shown that this 26 -
year global effort has not been in vain.»
Three basic mechanisms have been proposed over the
years to explain the formation of specific neural circuitry: (1) an elaborate predetermined
program encoded genetically in each neuron that unfolds according to rigid and unmodifiable rules, (2) a random process of
trial and error in which growing nerve fibers that make the right connections are consolidated and those that fail are reabsorbed and (3) a general
program of circuit formation that is brought to completion by an interplay between genetic and extrinsic factors.
We have one of the most comprehensive CAR T cell
programs in the world, with 14 CAR T clinical
trials ongoing and plans to open numerous additional
trials in the coming
year, including for patients with multiple myeloma, prostate cancer, liver cancer and breast cancer.
Any student that is enrolled in an accredited training
program is eligible for up to two
years of free -
trial membership during their training.
In the RV144 vaccine
trial, led by the U.S. Military HIV Research
Program at the Walter Reed Army Institute of Research, the efficacy at 3.5 -
years was 31.2 %; however, a higher early effect (60 %) was seen at 12 months.
Before joining Hookipa, he worked for 9
years at Novartis Oncology Translational Medicine as a Clinical
Trial Head and 3
years at Bayer Oncology Business Unit as a Clinical
Program Manager.
Reykjavik, ICELAND, December 17, 2004 — deCODE genetics (Nasdaq: DCGN) today announced the signing of an agreement under which it will conduct a Phase II information - rich clinical
trial next
year of a third - party compound as part of a drug development
program in asthma.
Included among the numerous recipients of Mr. Sanford's gifts, that total more than one billion dollars, are: the Edith Sanford Foundation for Breast Cancer that was created in 2012 by a gift of $ 100 million in honor of Mr. Sanford's mother who died of breast cancer when he was four
years old; the Sioux Valley Hospitals and Health System, which renamed itself Sanford Health in 2007, in recognition of a $ 400 million gift; a $ 125 million gift in 2014 to establish Sanford Imagenetics, a
program that will integrate genomic medicine into primary care for adults; the University of California San Diego which received a $ 100 million gift for the creation of the Sanford Stem Cell Clinical Center in 2013 to accelerate the translation of stem cell research discoveries by advancing clinical
trials and patient therapies; the Burnham Institute for Medical Research that received a $ 50 million gift in 2010, and recognized its appreciation for both this and a 2008 gift of $ 20 million to the Sanford Center for Childhood Disease research at Burnham by then changing its name to Sanford Burnham Medical Research Institute; a $ 70 million gift to establish a particle physics laboratory named the Sanford Underground Research Facility; and the San Diego Consortium for Regenerative Medicine which received a gift of $ 30 million in 2008 and expressed its gratitude by renaming itself the Sanford Consortium for Regenerative Medicine.
AFM supports each
year more than 400 research
programs, among them more than 30 clinical
trials in gene therapy or cellular therapy concerning for example muscular, eyes, skin or blood diseases.
This
program, currently in Phase 1 clinical
trials, is expected to extend the 5 - day shelf life of platelets to more than 2
years.
Reykjavik, ICELAND, December 17, 2004 — deCODE genetics (Nasdaq: DCGN) today announced the signing of an agreement under which it will conduct a Phase II information - rich clinical
trial next
year of a third - party compound as part of a drug development
program in...
His
program, The Lifestyle Heart
Trial, was published over 20
years ago.
So avoid the mistakes and confusion by using the same software
program I created and perfected after
years of
trial and error... a powerful formula for building muscle.
A randomized controlled
trial showed that in the
year after an EFT weight loss
program, participants lost an average of 11 lb [3].
My
programs (like The Psoriasis
Program and Candida Crusher, for example) often take several
years to perfect and is the result of much
trial and error and extensive clinical practice.
My Psoriasis
Program protocol took several
years to perfect and is the result of much
trial and error and extensive clinical practice.
After
years of much
trial and error, along with way too much frustration, disappointment and money spent on supplements, books, videos, I finally started to see
programs that worked and patterns of training that delivered me the rapid results I was after.
Irate that columnist George Will had questioned the benefits of early childhood education in a throwaway line in paragraph 15 of an op - ed, Heckman wrote, «Those benefits, quoted by President Obama this
year, come from my evidence - based analysis of more than 30
years of data from the Perry Preschool
program... It is as good a
trial for effectiveness as those we currently rely on to evaluate prescription and over-the-counter drugs.»
He proposes that each of the nation's 1,200 - plus school of education and teacher prep
programs conduct one randomized
trial on a teacher move each
year.
We are excited to lead the disruption of the
Year 8 Pastoral Care
program with a
trial of an externship model based on authentic opportunities to inform change at Wirreanda Secondary School.
Yet, despite those flaws, a randomized controlled
trial found that the
program led to gains equivalent to 10 percent of a
year's worth of learning in math and 11 percent in reading.
My proposal is that each of the nation's 1,200 - plus schools of education and teacher prep
programs conduct one randomized
trial on a teacher move each
year: Phase 1, Phase 2, or Phase 3.
This 20 -
year randomized controlled
trial examined the impact of social and emotional intervention
programs (such as social skills training, parent behavior - management training with home visiting, peer coaching, reading tutoring, and classroom social - emotional curricula) for 979 high - risk students in kindergarten.