Sentences with phrase «years of development from»

In this lecture, edited to approximately 4.5 hours, Paul clearly and succinctly presents an overview of the first 21 years of development from an anthroposophical perspective.
Also, with only a year of development from start to finish, the end package manages to become a real achievement from the team at Naughty Dog in terms of ambition.

Not exact matches

To start, he needed both people and funds — futuristic home doodads don't invent themselves — so he secured $ 12.5 million in subordinated debt financing from the Business Development Bank of Canada and Quebec's Fonds de solidarité FTQ, with flexible five - year payment terms (the latter a reward for years of solid financial management).
Our specially designed, proprietary Mathnasium Method ™, derived from more than 35 years of research and development, helps math make sense to kids.
In March of this year Energinet, along with TSOs from the Netherlands and Germany, signed a trilateral agreement relating to the development of a vast renewable electricity system, involving artificial islands, in the middle of the North Sea.
While we are still several years away, perhaps, from a suite of shark - antibody - connected drugs in the clinic, it's a promising area for development.
The miner, under the leadership of Executive Chairman John Thornton, has focused for the past three years on reducing debt by more than 50 percent from the more than $ 13 billion it hit at the end of 2014 due to overpriced acquisitions and mine development, including Pascua - Lama.
Andrew Pask, a 44 - year - old City of Vancouver neighbourhood planner, says he and his colleagues are called in to work on files that range in scale from single - parcel development applications to regional strategies.
Earlier this year, senior deputy Bank of Canada governor Carolyn Wilkins warned of job losses and greater income inequality stemming from AI and robotics, though she expects these technological developments to eventually create more jobs than they replace.
It all lends credence to Tehrani's claim that, from the outset 15 years ago, he sought to build a different kind of biotechnology firm — «a truly rational drug development company,» as he puts it.
She applied to The Flatiron School, and attended from September through December of last year learning web development at The Flatiron School.
The combined ratio of 97.5 % improved 2.1 points due to higher net favorable prior year reserve development (1.7 points) and a benefit (0.8 points) from catastrophe losses, partially offset by a higher underlying combined ratio (0.4 points).
In the opinion of the Company's management, a discussion of loss reserve development is meaningful to users of the financial statements as it allows them to assess the impact between prior and current year development on incurred claims and claim adjustment expenses, net and core income (loss), and changes in claims and claim adjustment expense reserve levels from period to period.
The combined ratio of 95.5 % decreased 0.5 points due to higher net favorable prior year reserve development (1.0 point), as well as a benefit (0.2 points) from catastrophes, partially offset by a higher underlying combined ratio (0.7 points).
Geoff Wilson, the founder and President of 352 Inc., an 18 year - old company that began in his dorm room and has grown to a multi-state digital product development powerhouse, credits 352 Inc.'s success on the organization's adoption of agile methodologies to all aspects of the business from coding to management.
blueRover only graduated from Waterloo's renowned Accelerator Centre two years ago, but already over 500 Sysco refrigeration trucks now use blueRover sensors to monitor the temperature inside their trailers, says Peter Smith, the company's director of business development in Canada.
It has already secured up to several billion dollars of financing from Chinese state - controlled banks, including the China Development Bank, for the project, which Mexico estimates will cost $ 10 billion over 10 years, one of the people said.
For instance, business spending on research and development has actually dropped to 0.89 per cent of gross domestic product in 2011 from 1.29 per cent 10 years earlier.
Other matching fund offers flooded in from techies, including Patrick Collison, chief executive of online payment company Stripe, and Nat Friedman, co-founder and chief executive of Xamarin, the software development company acquired last year by Microsoft (msft).
DTS earnings before tax of $ 13.1 million increased 16 % compared with $ 11.3 million in 2017, due to revenue growth and operating performance, as well as favorable developments related to self - insurance claims from prior years.
In peer countries like Canada, some citizens are taxed at higher rates throughout the year, the Organization for Economic Cooperation and Development notes, but they get a lot more from their government in terms of social services, including health care.
Actual results and the timing of events could differ materially from those anticipated in the forward - looking statements due to these risks and uncertainties as well as other factors, which include, without limitation: the uncertain timing of, and risks relating to, the executive search process; risks related to the potential failure of eptinezumab to demonstrate safety and efficacy in clinical testing; Alder's ability to conduct clinical trials and studies of eptinezumab sufficient to achieve a positive completion; the availability of data at the expected times; the clinical, therapeutic and commercial value of eptinezumab; risks and uncertainties related to regulatory application, review and approval processes and Alder's compliance with applicable legal and regulatory requirements; risks and uncertainties relating to the manufacture of eptinezumab; Alder's ability to obtain and protect intellectual property rights, and operate without infringing on the intellectual property rights of others; the uncertain timing and level of expenses associated with Alder's development and commercialization activities; the sufficiency of Alder's capital and other resources; market competition; changes in economic and business conditions; and other factors discussed under the caption «Risk Factors» in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sec.gov.
To fund the development of the app, AVOS, the company behind MixBit, raised venture capital money in April last year from Google Ventures, the China - based incubator Innovation Works, Madrone Capital and New Enterprise Associates.
IBM's decision to build out public and private clouds for infrastructure and application development won plaudits, but the researchers found that SoftLayer, which IBM (IBM) bought for $ 2 billion two years ago, has little to distinguish itself from competitors other than its mix of virtualized and non-virtualized bare - metal capabilities and broad geographic coverage.
It's Microsoft's most important franchise for the Xbox, and even though it's changed hands from Bungie to Microsoft - owned 343 Industries, the development team has twice shown us it's capable of Master Chief's mantle: first in 2012 with «Halo 4,» and this year with «The Master Chief Collection,» which remastered and remixed the first four major titles with new graphics and interesting gameplay additions like playlists.
His particular expertise is the top - secret document from 2008 that provided most of the magazine's revelations: A 50 - page «catalog» of NSA capabilities — some still under development five years ago, some already deployed.
In development for more than a year with input from top female Muslim athletes, the Pro Hijab is made of a breathable polyester mesh, in line with Nike's other high performance gear.
The fallout from the accident could stall the development and testing of self - driving vehicles, designed to eventually perform far better than human drivers and to sharply reduce the number of motor vehicle fatalities that occur each year.
Actual results, including with respect to our targets and prospects, could differ materially due to a number of factors, including the risk that we may not obtain sufficient orders to achieve our targeted revenues; price competition in key markets; the risk that we or our channel partners are not able to develop and expand customer bases and accurately anticipate demand from end customers, which can result in increased inventory and reduced orders as we experience wide fluctuations in supply and demand; the risk that our commercial Lighting Products results will continue to suffer if new issues arise regarding issues related to product quality for this business; the risk that we may experience production difficulties that preclude us from shipping sufficient quantities to meet customer orders or that result in higher production costs and lower margins; our ability to lower costs; the risk that our results will suffer if we are unable to balance fluctuations in customer demand and capacity, including bringing on additional capacity on a timely basis to meet customer demand; the risk that longer manufacturing lead times may cause customers to fulfill their orders with a competitor's products instead; the risk that the economic and political uncertainty caused by the proposed tariffs by the United States on Chinese goods, and any corresponding Chinese tariffs in response, may negatively impact demand for our products; product mix; risks associated with the ramp - up of production of our new products, and our entry into new business channels different from those in which we have historically operated; the risk that customers do not maintain their favorable perception of our brand and products, resulting in lower demand for our products; the risk that our products fail to perform or fail to meet customer requirements or expectations, resulting in significant additional costs, including costs associated with warranty returns or the potential recall of our products; ongoing uncertainty in global economic conditions, infrastructure development or customer demand that could negatively affect product demand, collectability of receivables and other related matters as consumers and businesses may defer purchases or payments, or default on payments; risks resulting from the concentration of our business among few customers, including the risk that customers may reduce or cancel orders or fail to honor purchase commitments; the risk that we are not able to enter into acceptable contractual arrangements with the significant customers of the acquired Infineon RF Power business or otherwise not fully realize anticipated benefits of the transaction; the risk that retail customers may alter promotional pricing, increase promotion of a competitor's products over our products or reduce their inventory levels, all of which could negatively affect product demand; the risk that our investments may experience periods of significant stock price volatility causing us to recognize fair value losses on our investment; the risk posed by managing an increasingly complex supply chain that has the ability to supply a sufficient quantity of raw materials, subsystems and finished products with the required specifications and quality; the risk we may be required to record a significant charge to earnings if our goodwill or amortizable assets become impaired; risks relating to confidential information theft or misuse, including through cyber-attacks or cyber intrusion; our ability to complete development and commercialization of products under development, such as our pipeline of Wolfspeed products, improved LED chips, LED components, and LED lighting products risks related to our multi-year warranty periods for LED lighting products; risks associated with acquisitions, divestitures, joint ventures or investments generally; the rapid development of new technology and competing products that may impair demand or render our products obsolete; the potential lack of customer acceptance for our products; risks associated with ongoing litigation; and other factors discussed in our filings with the Securities and Exchange Commission (SEC), including our report on Form 10 - K for the fiscal year ended June 25, 2017, and subsequent reports filed with the SEC.
Fearing the worst, the U.S. and Britain focused their resources into the Manhattan Project; from the blackboard to Hiroshima, the development of a fission device took a scant seven years.
At today's prices, industry forecasts of three million barrels per day by 2020 are likely to underestimate production by a bit, but the real kicker will be on the value of that production to all concerned — governments, via taxes and royalties, and shareholders will all suffer much lower returns from this development than they would have expected less than a year ago if prices stay where they are today.
Novo said obesity drugs will account for more than one third of its overall research and development spend this year, up from around 10 percent five years ago.
After five years of development, both hearts had issues: While the AEC heart remained clunky and inefficient, the NHI heart was riddled with technological bugs from overheating to letting blood clot up the pump.
Cytokinetics continues its 20 - year history of innovation with three new muscle biology directed compounds advancing from research to development in 2018.
Farrell would not say if this product grew out of an acquisition or from internal development but AWS reportedly bought Biba, a San Francisco startup specializing in collaboration software last year.
Among the factors that could cause actual results to differ materially are the following: (1) worldwide economic, political, and capital markets conditions and other factors beyond the Company's control, including natural and other disasters or climate change affecting the operations of the Company or its customers and suppliers; (2) the Company's credit ratings and its cost of capital; (3) competitive conditions and customer preferences; (4) foreign currency exchange rates and fluctuations in those rates; (5) the timing and market acceptance of new product offerings; (6) the availability and cost of purchased components, compounds, raw materials and energy (including oil and natural gas and their derivatives) due to shortages, increased demand or supply interruptions (including those caused by natural and other disasters and other events); (7) the impact of acquisitions, strategic alliances, divestitures, and other unusual events resulting from portfolio management actions and other evolving business strategies, and possible organizational restructuring; (8) generating fewer productivity improvements than estimated; (9) unanticipated problems or delays with the phased implementation of a global enterprise resource planning (ERP) system, or security breaches and other disruptions to the Company's information technology infrastructure; (10) financial market risks that may affect the Company's funding obligations under defined benefit pension and postretirement plans; and (11) legal proceedings, including significant developments that could occur in the legal and regulatory proceedings described in the Company's Annual Report on Form 10 - K for the year ended Dec. 31, 2017, and any subsequent quarterly reports on Form 10 - Q (the «Reports»).
Consider that over the past 20 years, software development has been the discipline from which some of the most radical breakthroughs in business have emerged.
Geer, the founder and president of Connecticut River Interactive LLC, a two - year - old Internet - development company, completed a deal for a $ 100,000 financing package from the Small Business Administration during the final days of October, «right in the middle of all that chaos,» he recalls.
Excluding proceeds from the equity financing completed in the first quarter and excluding other financing - related amounts (interest and royalty) and without the company's high level of research and development payments, most of which relates to advancing the REDUCE - IT study to completion this year, net cash outflow in the quarter ended March 31, 2018 was approximately $ 0.1 million.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
Today's must - read story is from Fortune «s Peter Elkind and it looks at the recent leadership developments at CBS (CBS) and Viacom (VIA), where 92 - year - old Sumner Redstone stepped aside from his long - held role as executive chairman of both companies.
Several Thai politicians who attended the Boao Forum for Asia, a kind of China - centered version of the World Economic Forum in Davos, noted that, in recent years, some of the discussions at Boao had shifted from a kind of general talk of globalization and its impact in Asia to more specific conversations about some of the failings of Western economic models exposed by the global economic crisis, and whether China's type of development might be less prone to such risks.
Prior to joining Icon, Narutomo spent ten years at Microsoft and nine years at Hewlett Packard in a broad range of business development roles from selling new software solutions to creating strategies for launching new products into the Japan market.
The most directly comparable GAAP financial measure is the combined ratio, which is computed by adding total incurred losses and LAE, including the impact of catastrophe losses and loss and LAE reserve development from prior years, with the insurance expense ratio.
Factors that could cause or contribute to actual results differing from our forward - looking statements include risks relating to: failure of DBRS to rate the Notes at the anticipated ratings levels, which is a closing condition, or at all; changes in the financial markets, including changes in credit markets, interest rates, securitization markets generally and our proposed securitization in particular; the willingness of investors to buy the Notes; adverse developments regarding OnDeck, its business or the online or broader marketplace lending industry generally, any of which could impact what credit ratings, if any, are issued with respect to the Notes; the extended settlement cycle for the scheduled closing on April 17, 2018, which may exacerbate the foregoing risks; and other risks, including those described in our Annual Report on Form 10 - K for the year ended December 31, 2017 and in other documents that we file with the Securities and Exchange Commission from time to time which are or will be available on the Commission's website at www.sec.gov.
The Florida Legislature is cutting short its help for affordable housing, diverting tens of millions of dollars each year from a trust fund meant to aid such housing developments.
The Web Media, Digital Agency provides excellent inbound link development services, with years of link building experience to acquire high quality inbound links from relevant authoritative sources.
GCHQ documents obtained from Mr. Snowden by The Guardian newspaper and shared with The Times reveal an intense focus over several years by British spies on the development of Muscular and a closely related project code - named Incenser.
Those controls reduced the scale of projects from gigawatts to megawatts and development times from decades to years.
In April of this year, debt and tax equity financing for the project was secured from Prudential Capital Group and U.S. Bancorp Community Development Corporation.
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