Sentences with phrase «years of trial tested»

By contacting the experienced Virginia personal injury attorneys at Cannella & O'Neal, you will have the power of over 30 years of trial tested experience on your side.

Not exact matches

When it comes to putting together a good signature skin - care routine, it can take years of trial, error, and drugstore product testing to find the right roster of favorites.

The trial was one of three scheduled for the first half of this year over claims that Volkswagen deceived customers with the deliberate rigging of emissions controls to perform differently when being tested than they do on the road.

It cost 5 million euros ($ 5232000) to build, and the road, with its 30,000 square feet of solar panels, is being tested over a two - year trial period to see if it can actually create enough energy to power the village's street lights.

Actual results and the timing of events could differ materially from those anticipated in the forward - looking statements due to these risks and uncertainties as well as other factors, which include, without limitation: the uncertain timing of, and risks relating to, the executive search process; risks related to the potential failure of eptinezumab to demonstrate safety and efficacy in clinical testing; Alder's ability to conduct clinical trials and studies of eptinezumab sufficient to achieve a positive completion; the availability of data at the expected times; the clinical, therapeutic and commercial value of eptinezumab; risks and uncertainties related to regulatory application, review and approval processes and Alder's compliance with applicable legal and regulatory requirements; risks and uncertainties relating to the manufacture of eptinezumab; Alder's ability to obtain and protect intellectual property rights, and operate without infringing on the intellectual property rights of others; the uncertain timing and level of expenses associated with Alder's development and commercialization activities; the sufficiency of Alder's capital and other resources; market competition; changes in economic and business conditions; and other factors discussed under the caption «Risk Factors» in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sec.gov.

The e-commerce giant, which started testing the program in India two years ago, plans to expand the trials throughout the rest of the US next year.

The readers, which were tested during a trial involving 40 churches last year, are capable of supporting 500 transactions without recharging, although the vast bulk of regular donating is expected to continue by standing order.

Might it have been because he knew the goal was now within his reach, that after three hard years of testing, trial, stress and many disappointments, giving, always giving, pouring out his mind, his heart, his very soul, spilling forth so readily the vibrant life that was within him in acts of healing, feeding, loving, might it have been with some relief he caught sight of the end of his long journey, glimpsed the goal which, fearful though it was to us, to him would mean fulfillment of his task, the long - expected climax and conclusion of his pilgrimage?

Developed by a Boston - based company, SmartSports, the SmartKage has been in a trial stage over the past year «'' which led to its installation at the Concord baseball school, one of just 100 test sites chosen across the country.

And so, over years of design, testing, trials, redesigns, and a whole lot of baby snuggles, the LÍLLÉbaby COMPLETE was born.

The highly - controversial decision to allow Australia's George Smith to return to action during his side's third Test defeat to the British & Irish Lions earlier this year despite having been clearly concussed has prompted one of a series of changes to the global trial of the Pitch Side Concussion Assessment (PSCA) protocol.

The trial will also test what remains of federal corruption law after the U.S. Supreme Court weakened it last year.

Nationally, Natale's words struck a chord as teachers everywhere are dealing with reforms similar to those implemented in Connecticut this year — a new teacher evaluation system, new academic standards known as the Common Core State Standards, and the trial of a new computerized testing system.

The researchers caution that the booster therapy used in their new study will not be available on the market or even for use in human trials anytime soon; it must await years of animal testing for safety and effectiveness first.

The team completed preliminary testing of the antibiotic release response in December and hopes to begin bandage trials on pigs within two years.

Also published today in Gynecologic Oncology is the end - of - trial data of the Roche Diagnostics ATHENA HPV trial that enrolled more than 47,000 women in a longitudinal, three - year study of Roche's HPV test.

Helicon completed a larger human trial of the drug to test for safety in 2008 (results are not yet available) and plans another trial this year.

He is also the principal U.S. investigator for a randomized trial that began late last year in Germany and is now being conducted here to test the value of nicotine as a therapeutic drug.

It typically takes many years to initiate such trials because of the stringent safety testing that must be done before testing in humans begins, but Reynolds said it may be possible to move faster as the therapy only involves modifying a patient's dietary intake and supplementing with a medium - chain triglyceride oil, both of which have no known side effects.

Drugs that disrupt the enzyme, his animal studies suggest, could prevent Alzheimer's with less risk of unwanted side effects — an approach that he expects to begin testing in human trials within three years.

The company plans in October to conduct a separate test specifically to study the seasonal flu vaccine's effectiveness among 480 elderly participants (a demographic often encouraged to get seasonal flu shots), and Phase III efficacy trials across a larger set of demographics are scheduled to begin early next year.

The participants, a 51 - year - old woman who retained some movement in her fingers and wrists and a 54 - year - old man who could still move one of his index fingers slightly, are participants in the BrainGate2 trial, which is testing a neural interface system allowing thoughts to control computer cursors, robotic arms and other assistive devices.

«Given a city like Philadelphia's prior experience with gun violence, the 29 percent reduction in crime reported in this trial could translate into hundreds of fewer shootings each year if the vacant land interventions tested here were scaled beyond just the locations of the study,» said Branas.

Saltarelli notes that the concept of using biomarkers to conduct smaller trials to test drugs wasn't widely embraced by industry 10 years ago.

Biden has also been talking to Los Angeles, California, oncologist and billionaire Patrick Soon - Shiong, who on 11 January announced an industry - led moonshot aimed at testing in clinical trials combinations of cancer immunotherapy drugs, one of most promising new cancer treatments in recent years.

Some 200 patients have received the virus as part of the trial, and the company expects to announce early results from the test by the end of the year.

Young also hopes the results, which should be compiled by the end of the year, will provide enough preliminary evidence to help raise funds for a larger trial testing the use of social media to combat abuse of a broader number of substances.

Paying to participate in a soon - to - launch clinical trial testing transfusions of young blood «offers the greatest potential for everyone in this room to add a lot of healthy years to their life,» Faloon said.

Last year a Monterey Calif. — based company called Ambrosia launched the first U.S. clinical trial to test the anti-aging effect of young blood in people, but participants had to pay to participate, raising ethical questions.

To evaluate whether the experimental treatment is safe and whether it might be able to reduce frailty, Maharaj plans to run a battery of baseline testing on each clinical trial participant before they get their first infusion of young plasma and then monitor their changes for two years: That means cognitive exams, questionnaires about their quality of life and their indicators of frailty, and tests to measure biomarkers he believes are linked with aging, such as telomere lengths and DNA methylation.

Since CGP3466B has already been tested in phase II clinical trials to (unsuccessfully) treat Parkinson's disease and ALS, it is known to be safe for humans, but the researchers caution that many more years of studies are needed to definitively show whether it is effective for preventing cocaine damage, first in mice, then in humans.

The drug still needs several years of animal testing before a human trial is conceivable, Cheng says.

They are also reaching out to drug industry partners to investigate the potential of initiating human trials to test glutamate blockers as PTSD therapeutics, which may take several years to assemble.

The development process often takes 15 to 20 years or more and requires virus cultivation, animal model testing, product formulation, immunogenicity testing and years of costly clinical trials.

Surprisingly, although billions of dollars are spent each year to test new drugs, the information these trials yield is often of little help to doctors trying to treat the patients right in front of them.

The Physicians» Health Study II (PHS II) remains the only randomized, large - scale, long - term trial to test whether a daily multivitamin reduced cardiovascular disease risk, and researchers found that after 11 years of follow up, there was no significant difference in risk of major cardiovascular disease (CVD) events among men who took a multivitamin compared to those that took a placebo.

Two years ago, the Office of the Gene Technology Regulator granted CSIRO permission to test the variety in a short - term trial in a small number of volunteers.

Two of three patients from the first clinical test published 2 years ago are also in remission more than 2.5 years later, one after relapsing and then receiving a PD - 1 inhibitor, says trial leader Gerald Linette of the University of Pennsylvania.

The plan is over the next few years to perform a trial run to assess the ability of the test to prospectively identify newborns with NPC.

Field trials of GM insect control have been under way for some time, including a recent test of Oxitec's mosquitoes in the Brazilian city of Jacobina, where mosquito populations plummeted by 79 per cent between June and December last year, the company claims.

The Cluster Randomized Trial of PSA Testing for Prostate Cancer (CAP) included 419582 men aged 50 to 69 years and was conducted at 573 primary care practices across the United Kingdom.

UNITY has completed a rigorous screening and preclinical testing process of candidate drugs, discovered in this study, and is launching a new clinical trial to assess its first drug, for patients with osteoarthritis of the knee this year.

Of the many thousands of compounds tested in cells and in animal models each year, only a few will enter clinical trialOf the many thousands of compounds tested in cells and in animal models each year, only a few will enter clinical trialof compounds tested in cells and in animal models each year, only a few will enter clinical trials.

In the $ 1.47 million, four - year grant called â $ œBiomarkers of Ischemic Outcomes in Intracranial Stenosisâ $ (BIOSIS), Emory researchers are analyzing blood samples from 451 patients from around the country who were enrolled in a study known as SAMMPRIS (Stenting and Aggressive Medical Management for Preventing Recurrent stroke in Intracranial Stenosis), the first randomized, multicenter clinical trial designed to test whether stenting intracranial arteries would prevent recurrent stroke.

In a Canadian trial involving 16 asthma patients, the procedure improved average air - flow rates in and out of the lungs, even when tested two years after treatment.

Whitehead and the other researchers said that in the case of dengue, the testing was warranted because they knew that the vaccine appeared to be effective at preventing dengue 1, 3 and 4 viruses through previous testing but needed to learn more about its impact on dengue 2 before proceeding to larger trials that could take three to 10 years and cost tens of millions of dollars.

The development of a safe and effective vaccine takes many years and needs to go through many different stages of testing, including work on cells, testing on animals and finally clinical trials on humans.

If successful, this method will be tested at scale by an industrial partner who will generate clinical - grade material for a Phase 1 trial at the end of this five - year grant.

Its Clinical Trials Center conducts 13 - 15 clinical studies per year, and in December initiated a Phase 2 clinical trial of an Ebola vaccine following its groundbreaking first - in - human testing of the Ebola vaccine that showed efficacy in Guinea last year.

Third, two other randomised controlled trials of homocysteine - lowering treatments have shown effects on cognition: a trial in which normal participants with baseline tHcy levels > 13 µmol / L were treated with folic acid (0.8 mg / d) for three years showed a beneficial effect on several cognitive tests [44].