Sentences with phrase «years of uncertainty about»

The trial could clear up years of uncertainty about the efficacy of metformin as a potential miracle drug.

These programs, which were discussed last month at a rare - diseases conference hosted by the Wellcome Trust Sanger Institute near Cambridge, UK, aim to provide a genetic diagnosis that could end years of uncertainty about a child's disability.

Not exact matches

They represent a wealth segment of $ 3.9 trillion in the U.S., and as they approach retirement, they are looking for help from financial services providers to resolve their uncertainty about the coming years, an uncertainty that includes concern about their long - term health.

Although the banks say the moves would be legal procedures that would have a minimum impact on their operations and jobs in Scotland, their warnings intensified concerns about an independent Scotland's ability to retain businesses — particularly during the months of financial uncertainty that would follow a vote to break the 307 - year union with England.

Hanging over everything has been the uncertainty about the company's plan to spin off its $ 26 billion stake in Alibaba, which was announced a year ago but was abandoned last month by the company's board of directors because of tax concerns.

An omnibus appropriations package, steel tariffs, regulatory work on the new tax law and general uncertainty about the nation's direction on policy and governing fueled K Street business during the first three months of this year.

This uncertainty seems to have led to increased levels of stress and anxiety, with 70 % of all US respondents reporting stress this year when thinking about retirement savings and investments, versus 67 % in 2015.5 Of those respondents who reported experiencing significant stress when thinking about their retirement savings, 65 % didn't know how much of their retirement savings they currently withdraw / spend or expect to withdraw / spend on an annual basis in retiremenof stress and anxiety, with 70 % of all US respondents reporting stress this year when thinking about retirement savings and investments, versus 67 % in 2015.5 Of those respondents who reported experiencing significant stress when thinking about their retirement savings, 65 % didn't know how much of their retirement savings they currently withdraw / spend or expect to withdraw / spend on an annual basis in retiremenof all US respondents reporting stress this year when thinking about retirement savings and investments, versus 67 % in 2015.5 Of those respondents who reported experiencing significant stress when thinking about their retirement savings, 65 % didn't know how much of their retirement savings they currently withdraw / spend or expect to withdraw / spend on an annual basis in retiremenOf those respondents who reported experiencing significant stress when thinking about their retirement savings, 65 % didn't know how much of their retirement savings they currently withdraw / spend or expect to withdraw / spend on an annual basis in retiremenof their retirement savings they currently withdraw / spend or expect to withdraw / spend on an annual basis in retirement.

The main issue for good, established companies here is not the risk to the long - term stream of cash flows, but to what extent the uncertainty about the coming year or two of earnings will frighten investors to sell at depressed prices (thereby pricing stocks to deliver even higher long - term returns).

In comparison, budgets over the 1994 - 95 to 2005 - 06 included explicit prudence of about $ 4 billion in year one, rising to $ 7 billion in year 5, reflecting the fact that uncertainty increases over time.

We initiated our Lloyds position in December 2011 when uncertainty about macroeconomic conditions, as well as about Lloyds's management succession, caused shares to fall 64 % over the course of the year.

Tying it together Of course, no one knows for certain what will happen this year, and if there's one defining truth of the markets, its that the only thing that's certain about them is uncertaintOf course, no one knows for certain what will happen this year, and if there's one defining truth of the markets, its that the only thing that's certain about them is uncertaintof the markets, its that the only thing that's certain about them is uncertainty.

Even after — or maybe because of — my years spent wandering the wilderness, in the midst of my doubts and questions and uncertainties, all of it, I still have stars in my eyes about Jesus.

It has been hard for me in this few years and I will do my best to hang on there until I reach my goal.I am not sure how long would it be for me to stay in the insurance business since there is many uncertainty about this kind of job.

a set of values, beliefs, and structure in a person's life in order to give them direction and a sense of right and wrong is fine, but organized religions are no more than large corporations, and like any large corporation are only focused on their bottom line... trying to control the public and extract as much money as they can from them by any means necessary... promoting fear, uncertainty, hate and a sense that they alone can offer salvation... for a price (although they are very cleaver about getting to this hidden and unspoken cost... after all these hundreds of years they have perfected their craft well!)

I am in mt mid 30's and in many ways I have becomes wiser as the years have passed by... but also the realization of uncertainty about a lot of issues.

The object of their scrutiny was a strapping, gray 3 - year - old named Holy Bull, who would lace Preakness and Belmont winner Tabasco Cat and about whom there was as much uncertainty as fascination, a deliciously fast horse, perhaps the horse all of racing has been waiting for.

With all the uncertainty swirling about whether he did or did not incur a penalty by causing his ball to move early into his final round of the U.S. Open, the guy whose mental makeup has been questioned over the years came up huge.

Though, with the changes proposed for next year, I believe the majority of fans will be happy as squads will be settled prior to the season commencing; fans will know the score and speculation and uncertainty about their star players will lessen.

Their letters provide a rich insight into their experiences of migration over 150 years: they're delighted by easy access to the labour market and higher salaries, for example, but also talk about the uncertainty of succeeding in the host country because of job insecurity and higher living costs.

Ongoing Brexit uncertainty, rising levels of concern about housing and the NHS, and a total lack of confidence in Theresa May mean that voters are feeling anxious and pessimistic about the year ahead.

Kaczynski said he hopes to win a second two - year term to guide the town's economic development, tax base growth, creation of a town center near the new train station, help hire a new town manager and keep taxes as low as possible despite the $ 1.7 billion state deficit and uncertainty about state aid to towns and cities.

«As employers of more than a million New Yorkers, we urge you to act now to end uncertainty about the future governance of our city schools and extend the current law for at least three years,» reads the letter, which was released by the Partnership for New York City.

Democrats in the state Senate gave Jennifer Shilling another two years as minority leader Tuesday, brushing aside a subpar performance at the ballot box that left Republicans with their largest majority in more than 40 years and uncertainty about whether Shilling will retain her own seat in the face of a recount.

He acknowledges the uncertainties about whether EV - D68 is the cause of acute flaccid myelitis, and even whether it will come back in another outbreak later this year.

ITER managers had decided to put off making a decision about installing the coils for a couple of years, but Motojima concluded earlier this month that the uncertainty was harming the project.

The AAAS Annual Meeting brings together more than 10,000 of the world's most talented and diverse scientists — yet this year select international participants who have made valuable contributions to the scientific community may not attend, due to ongoing uncertainty about the recent immigration and visa order implemented in the United States.

Those data, to be collected this year and next, could improve climate models, which account poorly for these atmospheric interactions and contain «horrific» uncertainties about the levels and behaviour of water vapour at stratospheric altitudes, Austin says.

And while 2017 hasn't ended yet and there's still a bit of uncertainty about the projections, Le Quéré noted that the last few years» projections have been accurate within about a half a percent or so.

Carling Hay et al. provide a statistical reassessment of the tide gauge record which is subject to bias due to sparse and non-uniform geographic coverage and other uncertainties and conclude that sea - level rose by about 1.2 millimetres per year from 1901 to 1990.

And according to revised cholesterol guidelines released last year, in cases where there's uncertainty about statin treatment, CRP level is one of several factors that doctors should consider in making the decision.

I suspect, moreover, that this complexity may take a still different form over the next year or so, as the tragedy of September 11 generates an upswing in support for government institutions, along with an increasing aversion to change and uncertainty — all of which could show up (temporarily) in the way people respond to survey items about vouchers.

If top graduates are put off going into teaching because of uncertainty about future pay and career prospects, we will struggle to maintain the improvements in pupil attainment that we have seen in recent years.

Tuesday morning questions and uncertainties swirled about in my mind as I trudged back to school; the concerns of the 120 16 - and 17 - year - olds I work with each day as a public high school American history teacher were far from a priority.

Chances are, parents, community leaders, and educators will be left years from now with an even greater sense of uncertainty about who really runs the district and to whom they should turn, or assign blame, when things go wrong.

The decision follows weeks of uncertainty about the future of the plantafter General Motors's withdrawal from the joint venture during its bankruptcy proceedings earlier this year.

In this tale of a six - year - old's last summer before starting school, a humorous and poetic text combines with surreal and multilayered artwork to create a unique, complex book about the universality of fear and uncertainty.

All of a sudden, everywhere you go, all these people in the prime of their Hipness Uncertainty Syndrome years are fondling cigars, puffing earnestly away on cigars, and — worst of all — droning away endlessly about cigars, as though cigars are an intellectual topic comparable to classical literature, as opposed to transient wads of spit - drenched tobacco.

«The real value [now] we think is in U.S. health care» because stocks of companies in that sector have been punished over the past couple of years because of uncertainty about health care reform, and government regulation, he said.

Gramercy Capital — There was a lot of uncertainty about the fate of GKK at the beginning of this year.

Elmgreen & Dragset — The artist - curators of this year's Istanbul Biennial speak to Nicole O'Rourke about what it means to be a «good neighbour», and the value of a unifying event in times of political uncertainty

NEW YORK — Despite continued uncertainty about the economy, many museums saw improvements in their financial health last year, reaping the benefits of cutbacks and other cautionary fiscal measures taken in the recent past.

What is clear is that uncontrolled emissions will very soon put us in range of temperatures that have been unseen since the Eemian / Stage 5e period (about 120,000 years ago) when temperatures may have been a degree or so warmer than now but where sea level was 4 to 6m higher (see this recent discussion the possible sensitivities of the ice sheets to warming and the large uncertainties involved).

«In terms of a risk assessment, the uncertainty range that one needs to consider is in my view substantially larger than 18 - 59 cm... [T] his discussion has all been about sea level rise until the year 2095.

Based on results from large ensemble simulations with the Community Earth System Model, we show that internal variability alone leads to a prediction uncertainty of about two decades, while scenario uncertainty between the strong (Representative Concentration Pathway (RCP) 8.5) and medium (RCP4.5) forcing scenarios [possible paths for greenhouse gas emissions] adds at least another 5 years.

Professor Curry has led debate in the science community about the process of reviewing climate change, including giving testimony before the US house subcommittee on environment this year, remarking on the many large uncertainties in forecasting future climate.

During recent years (1993 — 2003), for which the observing system is much better, thermal expansion and melting of land ice each account for about half of the observed sea level rise, although there is some uncertainty in the estimates.

Windchasers, «Which means that in about 10,000 years, his model of the uncertainty is supposed to include temperatures below absolute zero.»

With respect to the reported benefit - cost rations, this paper argues that they are a bit low because, first, they do not reflect the substantial concerns about equity and uncertainty; and second, because a substantial part of the benefits (after the year 2100) is not accounted for.

Nevertheless, 69 % of respondents from large carbon emitters indicate that their companies have cut emissions in anticipation of a carbon price, and 84 % expect their company to do so over the next three years - not withstanding significant uncertainty about whether the carbon price may be repealed.

The rate of 3mm / year is also roughly equivalent to the SLR budget from land ice melt and thermal expansion, though admittedly there is a lot of uncertainty specially about Antarctica.