Sentences with phrase «yeast as a model organism»

Protein misfolding and aggregation had been identified as a major factor in mad cow disease, and research using yeasts as model organisms played a large role in those findings.

«Using yeast as a model organism, we studied the Tup1 protein, a negative regulator of gene expression,» says Biology Professor Emanuel Rosonina, adding, «This protein binds to some genes and blocks their expression, helping to ensure genes that shouldn't be turned on remain inactive.»

The project takes advantage of yeast as a model organism and several reconstitution approaches to understand the particular function of the involved proteins.

Not exact matches

Years later, as I was wrapping up my Ph.D. after having spent countless hours centrifuging yeast, I couldn't wait to work with a new model organism.

Schizophrenia researcher Daniel Weinberger of the National Institute of Mental Health in Bethesda agrees that the paper adds to evidence that epistasis — which has been shown in model organisms such as yeast but difficult to prove in humans — is «robust and ubiquitous.»

A research group from the University of Seville has revealed the role that the protein Rrm3 plays in the repair of breaks that occur during the replication of DNA, by using the yeast Saccharomyces cerevisiae as a model organism.

Using a novel method they developed to map chromosome breaks in a model organism, the budding yeast, Wenyi Feng, Ph.D., of Upstate Medical University and her colleagues have discovered new information as to how and where chromosome fragile sites can occur in human DNA.

Given the rapid succession of generations in yeast, we can use it as a model organism — and study the mechanisms of aneuploidy in much greater detail to find out whether we can derive from it new approaches for diagnosing and treating human diseases.»

Genome sequencing, not of humans but of model organisms such as yeast and fruitfly, was in full swing by the late 1990s.

Geneticists across the model organism and human genetics communities recognize Hieter for his dedication to uniting human biologists with those who work on model organisms such as mice, fruit flies, worms, and yeast.