Sentences with phrase «yeast cell division»
Kim was quite receptive to the idea, so I set out to study yeast cell division.
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Yeast studies had suggested that Mus81 was critical for a specific stage in cell division that's essential for chromosome recombination during reproduction.
They found numerous genes activated in the XYL regulon - controlled yeast that upregulated pathways involved in growth, such as cell wall maintenance, cell division, mitochondrial biogenesis and adenosine triphosphate (ATP) production.
The researchers behind the new study say that the fact that this mechanism is highly similar in human cells and yeast cells suggests that it plays a key role in ensuring proper chromosome distribution following each cell division.
Dr Nadeau added «Our results are even more surprising because the cortex gene was previously thought to only be involved in producing egg cells in female insects, and is very similar to a gene that controls cell division in everything from yeast to humans.»
And if small RNAs influence cell division in humans as they do in yeast and Tetrahymena, minor disruptions in the machinery could lead to cancer.
A single yeast cell normally goes through about 30 cell divisions in its five - day life span.
In animal cells (as well as yeast cells), the microtubules that act to separate chromosomes during cell division are usually organized around a central structure.
«With the help of animal biologists, we found that chem7 had no effect on budding yeasts and human cells, which indicates that chem7 does not inhibit the cell division of animal cells.»
The assay uses time - lapse microscopy to monitor individual yeast cells undergoing a small number of divisions to form microcolonies.
Even when the researchers helped extend the cells» life spans by knocking out a problematic gene, the yeast DNA still started breaking down after 25 cell divisions.
To date, yeast has taught scientists a lot about cell division and DNA repair, processes that go wrong in cancer.
In yeast cells, the cell division cycle takes only 1.5 hours — meaning yeast have a very rapid succession of generations.
Detailed genetic analyses have now shown that the yeast cells individually multiply as many as six of their 16 total chromosomes during cell division, and can reverse this multiplication again.
Partly based on his MIT Ph.D. thesis research performed in yeast, Sheltzer suspects aneuploidy causes errors in DNA replication, as well as problems with chromosome segregation during cell division.
Aurora kinases are enzymes that control mitosis, the process of cell division, and were first discovered in the 1990s in yeast, flies and frogs.
Simon's strategy is to compare the effects of a drug on a normal strain of yeast and a strain with a mutation in one of the many genes that affect normal cell division - a property that is disrupted in cancerous cells.
The mechanistic complexity of the cascades will be explained using the examples of crucial Cdk1 targets including Sic1, the Cdk1 target and inhibitor controlling the G1 / S transition in budding yeast, and Far1, the molecule defining the decision between mating and entry into cell division.
fertilization in mice, he had switched to studying how yeast cells duplicate their genome during cell division.
Defeated by an initial project on in vitro fertilization in mice, he had switched to studying how yeast cells duplicate their genome during cell division.