August 2, 1996 Protein particles similar to those suspected in «mad cow» disease found in
yeast cells Researchers at the University of Chicago's Howard Hughes Medical Institute have shown that a defective cell trait can be propagated by a faulty protein, without any DNA or RNA serving as the genetic blueprint.
Not exact matches
The
researchers deployed this technology in
yeast cells that are genetically engineered to overproduce a protein associated with Parkinson's disease, known as alpha - synuclein.
To answer this question, the
researchers created numerous premature stop signs, known as nonsense mutations, in test genes in human and
yeast cells.
In a
Cell paper publishing September 8,
researchers describe a family tree of these microbes with an emphasis on beer
yeast.
In order to describe the mechanism of a membrane sensor which measures the degree of lipid saturation in the
yeast cell, the
researchers used genetic and biochemical methods and simulated the motions and underlying forces of membrane lipids over a period of a few milliseconds by means of extensive molecular dynamic simulations.
Already,
researchers have used CRISPR / Cas9 to edit genes in human
cells grown in lab dishes, monkeys (SN: 3/8/14, p. 7), dogs (SN: 11/28/15, p. 16), mice and pigs (SN: 11/14/15, p. 6),
yeast, fruit flies, the worm Caenorhabditis elegans, zebrafish, tobacco and rice.
«Protein isolated from baker's
yeast shows potential against leukemia
cells:
Researchers performed in vitro trials to test the effect of L - asparaginase on acute lymphoblastic leukemia
cells and published the results in Scientific Reports.»
The
researchers behind the new study say that the fact that this mechanism is highly similar in human
cells and
yeast cells suggests that it plays a key role in ensuring proper chromosome distribution following each
cell division.
The team of
researchers, led by
yeast cell biologist Susan Lindquist of the University of Chicago, had demonstrated last year that a metabolic trait in
yeast called [PSI +] could be passed from one generation to the next without changes in the
yeast's DNA.
Researchers at Tufts University have created a genetically modified
yeast that can more efficiently consume a novel nutrient, xylose, enabling the
yeast to grow faster and to higher
cell densities, raising the prospect of a significantly faster path toward the design of new synthetic organisms for industrial applications, according to a study published today in Nature Communications.
In a study led by the University of Montana and co-authored by Purdue mycologist M. Catherine Aime,
researchers show that lichens across six continents also contain basidiomycete
yeasts, single -
celled fungi that likely produce chemicals that help lichens ward off predators and repel microbes.
Researchers in this study used budding
yeast, creating populations of
cells with more than 10 million different randomised genomes, to investigate how genetic diversity affected resistance.
«
Researchers ID cancer gene - drug combinations ripe for precision medicine:
Yeast, human
cells and bioinformatics help develop one - two punch approach to personalized cancer therapy.»
The
researchers ended up with 172 drug - gene mutation combinations that successfully killed both
yeast and human cancer
cells.
A
yeast retrotransposon called Ty3, the
researchers have found, is especially judicious: it always inserts itself in safe places, outside genes rather than inside them, and only near genes of which a
yeast cell has many copies.
After inserting more than 400 human genes into
yeast cells,
researchers found that almost half of the human genes actually worked and kept the
yeast alive!
A team of
researchers at the Center for Molecular Biology of Heidelberg University (ZMBH) has recently discovered that in
yeast cells, the amount of nutrients that
cells are exposed to can affect DNA surveillance and repair mechanisms and therefore the quality of their DNA.
Even when the
researchers helped extend the
cells» life spans by knocking out a problematic gene, the
yeast DNA still started breaking down after 25
cell divisions.
The
researchers also engineered a
yeast strain where a mutant condensin was produced by the
cell when it went into figurative labor.
Researchers in OIST's G0
Cell Unit used fission
yeast to find the binding sites of this particular protein complex along chromosomal DNA.
Now,
researchers reporting in the
Cell Press journal
Cell Reports on October 9th have discovered why the
yeast (formally known as S. cerevisiae) make that smell: the scent attracts fruit flies, which repay the
yeast by dispersing their
cells in the environment.
And
researchers at the «Seattle project», an effort funded by the National Cancer Institute to find new anticancer drugs, are mutating genes in
yeast cells — such as the ATM gene or the mismatch repair genes — that often lead to cancer in humans.
The
researchers built a transistor that contains carbon nanotubes and antibodies programmed to attack the Candida
yeast cells.
To determine which strains yielded increased lifespan, the
researchers counted
yeast cells, logging how many daughter
cells a mother produced before it stopped dividing.
Last year,
researchers working to synthesize the genome of a strain of
yeast began to eye a much bigger prize: assembling from scratch the 3 billion base pairs of DNA that drive a human
cell.
Researchers have previously demonstrated that
yeast, fruit fly
cells and some types of human
cells grown in lab dishes divvy up proteins unequally.
Light played a key role in the experiment because it allowed the
researchers to switch on genes that they had added to the
yeast cells.
After inserting more than 400 human genes into
yeast cells one at a time,
researchers found that almost 50 % of the genes functioned and enabled the fungi to survive.
Researchers know that the
cells of species such as
yeast, flies and humans make far more RNA molecules — copied from DNA — than they seem to need.
In one experiment,
researchers sifted through a protein library produced in
yeast cells to select antibodies that bound most tightly to a cancer target.
October 21, 1994 Immortalizing agent of tumor
cells found in
yeast Researchers at the University of Chicago Medical Center have isolated the gene for a component of the elusive molecular machinery that plays a key role in making cancer
cells immortal.
Now,
researchers at Harvard and Massachusetts General Hospital (MGH) and their colleagues have shown that amyloid - β can protect against
yeast and bacterial infections in two animal models, as well as in cultured human
cells.
To be able to better measure the properties of the protein, the
researchers introduced the genetic information for the BvSUT1 protein into
yeast cells or into the ova of an African clawed frog.
The
researchers looked at whether longer CAG repeats in ataxin - 2 made the
yeast ALS
cells worse, and found that they did.
MEDFORD / SOMERVILLE, Mass. (March 26, 2018)--
Researchers at Tufts University have created a genetically modified
yeast that can more efficiently consume a novel nutrient, xylose, enabling the
yeast to grow faster and to higher
cell densities, raising the prospect of a significantly faster path toward the design of new synthetic organisms for industrial applications, according to a study published today in Nature Communications.
However, using a new technique known as sensitivity - enhanced nuclear magnetic resonance (NMR), Whitehead Institute and MIT
researchers have shown that they can analyze the structure that a
yeast protein forms as it interacts with other proteins in a
cell.
In the
Cell paper, the
researchers analyzed a
yeast protein called Sup35, which Lindquist's lab has been studying for many years.
The
researchers note that in the mammalian brain, whose
cells do not divide, prions pass between
cells and function as infectious agents; in
yeast, they produce heritable changes from one generation to the next.
Researchers at SciLifeLab have shown that a high - throughput method using microfluidic droplet sorting of mutated
yeast cells can be used to improve the production of industrial enzymes.