Sentences with phrase «yeast cells at»

The study uses a new technique that can keep track of thousands of yeast cells at once.

Not exact matches

He spent his last year as a Lisbon student studying cell - cycle regulation in yeast at the University of Manchester in the United Kingdom, with an Erasmus scholarship from the European Commission.

Upon joining the lab, Lee chose a high - risk project — «it sounded like more fun,» she says — aimed at determining whether a key gene in the yeast cell cycle, cdc2, was also present in human cells.

A research group at the Buchmann Institute for Molecular Life Sciences (BMLS) of Goethe University in Frankfurt, together with colleagues at the Max Planck Institute of Biophysics, has now discovered how yeast cells measure the availability of saturated and unsaturated fatty acids in foodstuffs and adapt their production of membrane lipids to it.

Brewer's yeast cells break down inedible sugars in their environment into edible ones, meaning that individuals get a boost from the work of their neighbors — especially at high densities.

She still does not know why he considered her at the time — «Maybe it was just my enthusiasm,» she wonders — but he nonetheless became her mentor as she studied the transcriptional activation of the cell - cycle regulated HO gene in the yeast Saccharomyces cerevisiae.

Researchers at Tufts University have created a genetically modified yeast that can more efficiently consume a novel nutrient, xylose, enabling the yeast to grow faster and to higher cell densities, raising the prospect of a significantly faster path toward the design of new synthetic organisms for industrial applications, according to a study published today in Nature Communications.

The new work is «solid,» says John Dueber, a synthetic biologist at the University of California, Berkeley, who is working on splicing morphine synthesis genes into yeast cells.

Wyrick and WSU colleagues Peng Mao, Michael Smerdon and Steven Roberts irradiated yeast cells and looked for patterns of damage at the level of individual base pairs, the DNA building blocks whose order serves as an organism's blueprint.

A team of researchers at the Center for Molecular Biology of Heidelberg University (ZMBH) has recently discovered that in yeast cells, the amount of nutrients that cells are exposed to can affect DNA surveillance and repair mechanisms and therefore the quality of their DNA.

But Judith Berman, a yeast geneticist at the University of Minnesota, Twin Cities, has shown that in another species, Candida albicans, some cells with extra chromosomes are more resistant to drugs.

By adding measured amounts of anhydrotetracycline (ATc) to a population of genetically modified yeast cells, scientists at the University of Texas M. D. Anderson Cancer Center were able to precisely control the production of green fluorescent protein.

And researchers at the «Seattle project», an effort funded by the National Cancer Institute to find new anticancer drugs, are mutating genes in yeast cells — such as the ATM gene or the mismatch repair genes — that often lead to cancer in humans.

As the cells get older, they acquire clumps of proteins and extra pieces of DNA, but when Angelika Amon at the Massachusetts Institute of Technology and colleagues tracked spores from old and young yeast cells they found that such abnormalities disappeared, meaning all spores had the same lifespan.

To look at the effects of heat shock on native populations of proteins, Drummond and his colleagues utilized a novel set of techniques that allowed them to simultaneously track almost 1,000 different mature proteins in yeast cells.

After inserting more than 400 human genes into yeast cells one at a time, researchers found that almost 50 % of the genes functioned and enabled the fungi to survive.

«So, the flexibility of yeast cells does not arise from the activity or inactivity of a single gene,» project head at ISB, Dr. Aimée Dudley, explains.

Yeast cytokinesis occurs at the microcompartment of the bud neck and involves the controlled synthesis of cell wall components.

October 21, 1994 Immortalizing agent of tumor cells found in yeast Researchers at the University of Chicago Medical Center have isolated the gene for a component of the elusive molecular machinery that plays a key role in making cancer cells immortal.

Now, researchers at Harvard and Massachusetts General Hospital (MGH) and their colleagues have shown that amyloid - β can protect against yeast and bacterial infections in two animal models, as well as in cultured human cells.

William Ratcliff, a biologist at the Georgia Institute of Technology in Atlanta, and his collaborators have discovered a surprisingly simple route to multicellularity: a single mutation in yeast that adheres the mother cell to its daughter to create a snowflake - like shape.

They used yeast cells to model the disease, which allowed them to look at over 5,000 genes to map out which ones caused more or fewer cells to die.

August 2, 1996 Protein particles similar to those suspected in «mad cow» disease found in yeast cells Researchers at the University of Chicago's Howard Hughes Medical Institute have shown that a defective cell trait can be propagated by a faulty protein, without any DNA or RNA serving as the genetic blueprint.

«At the basic level, yeast cells are very similar to mammalian cells.

They're looking at growing antibodies not only in mice, but also in insect, plant and yeast cells.

The researchers looked at whether longer CAG repeats in ataxin - 2 made the yeast ALS cells worse, and found that they did.

MEDFORD / SOMERVILLE, Mass. (March 26, 2018)-- Researchers at Tufts University have created a genetically modified yeast that can more efficiently consume a novel nutrient, xylose, enabling the yeast to grow faster and to higher cell densities, raising the prospect of a significantly faster path toward the design of new synthetic organisms for industrial applications, according to a study published today in Nature Communications.

«It was remarkable that the compound rescued yeast cells and patient neurons in similar ways and through the same target — a target we would not have identified without yeast genetics to guide us,» says Khurana, a postdoctoral scientist in the Lindquist lab and a neurologist at Massachusetts General Hospital who recruited patients for participation in this research.

«We found that a heritable genetic element based on protein folding, not encoded in DNA or RNA, allows yeast to acquire many silent changes in their genome and suddenly reveal them,» said Susan Lindquist, PhD, professor of molecular genetics and cell biology at the University of Chicago, Howard Hughes Investigator and principal author of the study.

«Although we first became aware of prions because they cause several bizarre neurological diseases, the discovery that something so awesomely similar happens in organisms as different as humans and yeast makes us suspect that there is a fundamental, common biochemical process at work here,» said study director Susan Lindquist, PhD, professor of molecular genetics and cell biology and an investigator in the Howard Hughes Medical Institute at the University of Chicago.

To assess the breadth of such protein - based inheritance, the lab of Whitehead Member Susan Lindquist lab devised an unbiased screen that examines all proteins in yeast for those capable of producing stable phenotypes that are passed from mother to daughter cells for at least 100 generations.

October 5, 2015 / Novato, California Following an exhaustive, ten - year effort, scientists at the Buck Institute for Research on Aging and the University of Washington have identified 238 genes that, when removed, increase the replicative lifespan of S. cerevisiae yeast cells.

Researchers at SciLifeLab have shown that a high - throughput method using microfluidic droplet sorting of mutated yeast cells can be used to improve the production of industrial enzymes.

Lysine ‐ 79 of histone H3 is hypomethylated at silenced loci in yeast and mammalian cells: a potential mechanism for position ‐ effect variegation