Not exact matches
The researchers deployed this technology in
yeast cells that are genetically
engineered to overproduce a protein associated with Parkinson's disease, known as alpha - synuclein.
«Let them eat xylose:
Yeast engineered to grow efficiently on novel nutrients: Discoveries may lead to faster growth and higher
cell densities in biological
engineering applications.»
The researchers also
engineered a
yeast strain where a mutant condensin was produced by the
cell when it went into figurative labor.
Several research teams had reasoned that if
yeast cells could be
engineered to express mannosidase, the
cells wouldn't produce the mannose - rich sugar complexes that are so immunogenic to humans.
The group took the first step toward their goal of a novel
engineering strategy for
yeast by creating what is known as a cDNA library: a collection of over 90 % of the genes from the genome of baker's
yeast (Saccharomyces cerevisiae), arranged within a custom segment of DNA so that each gene will be, in one version, overactive within a
yeast cell, and in a second version, reduced in activity.
Lundblad's group has
engineered yeast cells that lack telomerase, to study how
cells respond to eroding telomeres when telomerase is not present to counter-balance.
They blow up because Maselko's technology instructs the
cell to generate an immense amount of proteins caused by that particular gene — but only when the
engineered yeast mate with wild versions.
Because
yeast cells are eukaryotic, like human
cells, the approach could be a powerful new way to
engineer humanlike proteins and
cell pathways.
Here I was, this finely - trained
engineer who could build any electrical circuit she wanted, or
engineer yeast cells to glow green, but I wasn't
engineering losing the 20 pounds that I knew would make me happy.