Sentences with phrase «yeast cells lacking»

Not exact matches

There were hints that a chaperone called heat shock protein 104 (Hsp104) was different: Cell biologist Susan Lindquist of the University of Chicago and her colleagues had shown that yeast lacking Hsp104 couldn't dissolve protein clumps as well as normal controls — suggesting that Hsp104 was needed to untangle gnarled proteins.

Although lacking specialized cell types found in higher organisms and unsusceptible to cancer, Simon said that yeast is often a suitable model for preliminary drug screening before the drug's potential is evaluated in mammalian cells.

Lundblad's group has engineered yeast cells that lack telomerase, to study how cells respond to eroding telomeres when telomerase is not present to counter-balance.