Sentences with phrase «yeast vacuole»
Usually yeast vacuoles were too small to see under the light microscope, but in the mutant yeast, they grew so large they were easy to observe.
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Ohsumi then used chemicals to induce more mutations in the yeast strains, looking for cells that failed to form visible vacuoles even when they were starving.
When they starved the yeast, the scientists found that the cells developed unusually large vacuoles, the cellular garbage dumps that collect materials to be recycled.
When he moved back to Tokyo in 1977 to the lab of Yasuhiro Anraku, Ohsumi continued with his new study subject, but worked on transport systems that moved small molecules like amino acids and calcium into and out of the yeast version of the lysosome (idiosyncratically known by yeast biologists as the vacuole — which means «empty space»).
Recently, he has been focusing on the regulation of a family of yeast purine - cytosine permeases, including the transcriptional controls over their expression, and how, after these proteins bind to their cargo, they are targeted by the ubiquitin system for endocytosis and delivery to the vacuole.