Sentences with phrase «yield targets for»
A decade ago she became passionately engaged in efforts to help find a solution for malaria, investigating structures that might yield targets for new drugs.
https://www.cshl.edu/ Not exact matches
GIC Chief Investment Officer for fixed income Liew Tzu Mi said on Thursday that the Singapore wealth fund was targeting fixed income investments with selective emerging markets which were likely to converge with lower - yielding developed markets.
For instance, Morningstar found that passively managed target - date funds tend to have fewer holdings in high - yield bonds and Treasury inflation - protected securities than their actively managed counterparts.
target and maximum levels, assumed, for Mr. Hoyt's Wholesale Banking Group, continued double - digit loan growth and favorable credit quality; for Mr. Oman's Home and Consumer Finance Group, improvement in the home mortgage business due to cost control and expected improvements in the yield curve favorably affecting earnings from hedging activities; and for Ms. Tolstedt's Community Banking Group, growth in deposits, especially low or no - cost core deposits, continued loan growth, and stable credit loss rates.
This yields our target price of 3,000 for the S&P, up 12 % from current levels, by the end of 2018.
Taking all of your learnings from your target audience and formulating them into an actionable marketing plan will yield the response you had always hoped for.
Note that the real interest rates exceed reported for TIPS because I have adjusted yields to reflect the 35 basis point average difference between the Consumer Price Index used in calculating TIPS coupons and the Personal Consumption Expenditures deflator targeted by the Fed.
On the short - side of the yield curve, the consensus seems to interpret the Federal Open Market Committee's recent use of the word «gradual» as an indication that it will allow inflation to run higher than 2 % in order to make up for the last 20 years of below - target growth.
He controls for multiple economic and financial variables likely to be related to stock market returns (gross domestic product, industrial production, unemployment rate, consumer price index, Federal Funds target rate, term spread, credit spread and dividend yield).
The target for my Portfolio is to have an average yield of no less than 3.5 %.
While WestJet prepares to launch Swoop on June 20 in response to other ULCC competitors such as Flair Airlines Ltd., Air Canada has maintained its focus on targeting the premium passenger, driving higher yields for the company.
And judging by the index bond yields, inflation will average well below target for the next 10 to 20 years.
It is above my own minimum yield target of 2.7 %, and it also qualifies as «enough» for most dividend growth investors.
Given term premium suppression (via QE) reduced volatility and induced investors to buy risky assets to boost returns, a sustained rise in long - term interest rates would give investors more options to achieve yield targets, thus making risk assets appear less attractive and ultimately erode demands for yield and tighten financial conditions.
The Fed's reminder that its inflation target was symmetric was a clear negative for Treasury yields, and so the US currency's recovery was encouraging for dollar bulls, Callow said.
An alternative, and perhaps more likely, interpretation is that the market expects that the target cash rate will remain below its average over recent years for some time, and this expectation is reflected in bond yields.
Dataxu has today (April 17) announced the launch of an audience targeting service that will let advertisers target viewers of addressable, connected and linear TV services from a single platform which it claims will improve yield for media owners, increase efficiency for advertisers as well as reduce ad load time.
The new policy would target not just short - term rates but also long - term JGB yields under the guideline for market operations decided at every Monetary Policy Meeting.
This saw the cash rate move above its target of 5 per cent for a time, and the yield on Treasury Notes, which are eligible for purchase by the Reserve Bank in the course of its market operations, move to 50 basis points below that for bank bills (from normally about 10 basis points below).
The two dividend funds will target companies that are «expected to continue to pay and grow their dividends,» but the Fidelity Dividend ETF for Rising Rates will refine that to include companies that are expected to have returns that correlate positively with rising 10 - year U.S. Treasury yields, according to the prospectus.
The Bank of Japan expanded monetary stimulus on July 29 through a modest increase in purchases of exchange - traded funds (ETF), yielding to pressure from the government and financial markets for bolder action to spur growth and accelerate inflation towards its 2 percent target.
They include: high levels of degraded soils; reductions in irrigation quotas to restore the health of the Murray - Darling system; the re-forestation of some agricultural land to meet emissions reductions targets; the impacts of peak oil, such as the diversion of food crops into feed - stock for biofuels; and the price and crop yield implications of peak phosphorous, given Australia's dependence on imported fertilisers.
Reaction: De Bruyne is my Man City blueprint — Guardiola (Premier League) Report: De Bruyne makes it sweet 16 for awesome Man City (Premier League) Report: Otamendi wins derby to fire Man City 11 points clear (Premier League) Reaction: Klopp calls for Liverpool focus after Euro spree (Champions League) Report: «Fab Four» fire seven - goal Liverpool into last 16 (Champions League) Reaction: Mourinho pledges only «the truth» on injuries (Champions League) Report: Lukaku and Rashford send Man United into last 16 (Champions League) Reaction: Mourinho wants new shooting boots for Lukaku (Premier League) Report: Old boy Young downs Watford to lift Man United (Premier League) Reaction: Klopp looks on bright side after Chelsea draw (Premier League) Report: Willian denies Liverpool morale - boosting win (Premier League) Reaction: Guardiola targets Champions League milestone (Champions League) Report: Sterling strikes late to earn Man City top spot (Champions League) Report: Young England stifle Neymar's Brazil (friendly) Reaction: Loftus - Cheek showed he can cut it — Southgate (friendly) Report: New boys impress as England hold Germany (friendly) Reaction: Mourinho defends lack of Lukaku charity (Champions League) Report: Hapless Svilar helps Man Utd to brink of last 16 (Champions League) Reaction: «Stand up and be counted», Klopp tells Liverpool (Premier League) Report: Spurs» Kane rips sorry Liverpool to shreds (Premier League) Reaction: Guardiola proud to beat «best opponents» Napoli (Champions League) Report: Jesus earns Man City narrow win over Napoli (Champions League) Reaction: Mourinho and Klopp at odds over Anfield stalemate (Premier League) Report: Man Utd held at Liverpool as Mourinho parks the bus (Premier League) Report: McClean breaks Welsh hearts as Ireland reach play - offs (2018 World Cup) Reaction: Southgate admits England have long way to go (2018 World Cup) Report: Kane sends lacklustre England to World Cup (2018 World Cup) Reaction: Man City's show of force thrills Guardiola (Champions League) Report: Chelsea old boy De Bruyne gives Man City crucial win (Champions League) Reaction: «Amazing» Lukaku won't lose focus — Mourinho (Champions League) Report: Lukaku and Martial lead Man United in CSKA rout (Champions League) Reaction: Klopp says Liverpool on track despite stalemate (Champions League) Report: Coutinho scores as Liverpool held in Moscow (Champions League) Reaction: Man United part of «second level», says Mourinho (Champions League) Report: Fix - it Fellaini gets Man United off the mark (Champions League) Reaction: De Bruyne masterclass leaves Guardiola purring (Premier League) Report: Mané sent off as five - star Man City crush Liverpool (Premier League) Reaction: Alli gesture takes shine off England win (2018 World Cup) Report: Rashford redemption sends England closer to Russia (2018 World Cup) Reaction: Klopp hopes Euro progress yields transfer lift (Champions League) Report: Can brace gets Liverpool back into big time (Champions League) Report: Sterling rescue act spares 10 - man Man City (Premier League) Reaction: Conte happy for Chelsea to play the hunters (Premier League) Report: Alonso ruins Spurs» Wembley house - warming (Premier League) Report: Lukaku double fires Man United to winning start (Premier League) Reaction: Wenger lauds Giroud after Arsenal edge Leicester (Premier League) Report: Giroud earns Arsenal madcap opening win (Premier League) Reaction: Wenger fearful of another slow Arsenal start (Community Shield) Report: Courtois and Morata gift Arsenal victory at Wembley (Community Shield)
For instance, we know that say, targeting a supporter who's responded to your past global - warming emails with a climate - themed fundraiser is likely to yield better results than a less - targeted appeal.
However at 10.75 %, the yield on the bond is still much higher than government's initial target of 8.5 % and also higher than the previous one which had coupon rates of 8 % and 8.5 % percent for its $ 2 billion bond issued.
The agency typically looks for adaptive reuse projects to yield returns in the 10 percent to 12 percent range after incentives are factored in, so the estimated returns on the Christian Science Reading Room renovation would be two to nearly three times higher than that target level if the tax breaks were approved.
The authors suggest that therapies targeting TP53 mutations may yield better clinical outcomes for patients with HPV - inactive tumors.
But even when the genetic mechanism is more complex, he adds, the new approach might yield insights into underlying disease processes that could pave the way for more finely targeted treatments.
While the commercial potential might not be immediate, Duncan says the collaboration could yield concrete rewards for the companies, such as new R&D avenues from identification of novel drug targets.
«And while the tumor model we're now studying doesn't present targets for new drugs, if we can discover the mechanism controlling that model, it may yield therapeutic drug targets.»
The most efficient EGSs form transfer RNA precursor - like structures with the target RNA, in which the analog of the anticodon stem has been disrupted, an indication that selection for the optimal substrate for ribonuclease P yields an RNA structure different from that of present - day transfer RNA precursors.
One point of contention is whether validation should be considered «pass / fail,» or whether it should yield a ranking to score different antibodies as better or worse than others for the same target and application.
«Biologists uncovers a genetic mechanism that could enhance yield in cereal crops: Precise regulation of plant hormones in early reproductive development as a target for yield increases.»
Her team integrates both computational and experimental approaches to explore how perturbations to these gene networks can alter morphology, both within a species and across the grasses, with the ultimate goal of defining targets for improving grain yield in cereals.
However, the Clean Air Act is not the ideal vehicle for cutting greenhouse gas emissions, Parenteau said, suggesting that pricing carbon would yield better and faster results than setting compliance targets for individual states.
The colorful snails yielded the first hint that these calcium channels could make a potent target for pain relief.
Although this link remains to be tested directly, understanding its mechanism could yield an important target for disrupting the psyllid - CLas interaction.
Large - scale genetic and protein screening yields several possible targets for treating the debilitating neurodegenerative disorder
In agriculture, aid and research are helping to boost productivity through targeted interventions aimed at improving crop yields, capturing water for irrigation and providing advice on selling surplus produce.
This study is good example of a precision medicine themed approach to showing how a mechanistic understanding of the differential gene expression can yield biomarkers that can be used for early detection of disease, as well as potential therapeutic targets.
In order to most rapidly realize the value of genetics for human health, deCODE is currently partnering with life sciences companies to accelerate their target discovery, validation, and prioritization efforts, yielding improved patient stratification for clinical trials and essential companion diagnostics.
«Targets for CRISPR will be the same as those for classical breeding technologies, i.e., technologies are changing but the problems are the same: increasing yield, biotic and abiotic stresses resistant, better quality, etc..
With new technology for generating reams of genomic and molecular data, few scientists need convincing of the potential for big data — combined with clinical information from individual patients — to yield big answers for targeted cancer treatments.
«It presents a promising target for research into techniques that could help improve plant photosynthesis and crop yields.»
Agrigenomics - or the application of genomics in agriculture - is a key tool to easily identify targets for selective breeding programs to increase yield, facilitate drought tolerance, or select a variety of desirable traits.
«Treatments that target just a few of these genes or the proteins they make could yield substantial benefits for patients.
There is no need for PCR or cloning, as digestion of the destination vector with SapI yields 2 sites - the first site accepts the sgRNA target sequence for U6 promoter expression and the second site accepts the homology arm repair template.
The analytical sensitivity for each target gene RNA was in the range of 1 to 109 spirochetes, with a yield of detection close to 90 % of the calculated amount of known target in each sample.
It is important to regard the LGM studies as just one set of points in the cloud yielded by other climate sensitivity estimates, but the LGM has been a frequent target because it was a period for which there is a lot of data from varied sources, climate was significantly different from today, and we have considerable information about the important drivers — like CO2, CH4, ice sheet extent, vegetation changes etc..
Staining with this multi-color staining workflow yields similar localization patterns as cells stained for one target (compare nanobodies staining in figure 4A vs 4B).