Plasma from old mice didn't have a strong effect when injected into
young mice genetically engineered to lack VCAM1 in certain blood - brain barrier cells.
Researchers at the University of Southern California have developed a prostate cancer vaccine that prevented cancer in 90 percent of
young mice genetically predestined to develop the disease.
Not exact matches
Irina Conboy, a neurologist at the University of California, Berkeley, and her colleagues have performed extensive parabiosis experiments stitching together
young and old
mice that have been
genetically matched.
One mode of aging transmission is to give
genetically identical
mice transfusions of
young or old blood.
Yang's group took advantage of
genetically engineered
young mice that have protein markers which glow in response to changes in nerve function.
For example,
Young's research shows normally monogamous prairie voles do not develop pair bonds with their mates if their mu - opioid system is blocked; other studies have found that
mice genetically engineered to have no mu - opioid receptors do not prefer their mothers to other
mice the way normal baby
mice do.
The investigators could compare the insulin - producing beta cells from these
mice with those from
younger,
genetically identical
mice to examine the characteristics of the cells across the
mouse lifespan.
To do that, he and his colleagues are studying 32 lines of
genetically - defined
young, middle - aged and old
mice.