Sentences with phrase «young mice with»

And to do so, Ottersbach and her team are trying to understand how the disease might begin, even before birth, by looking at cells in the lab as well as young mice with the disease.

Previous studies have shown that young mice with specific immune system defects are susceptible to Zika infection.

The authors went on to study young mice with white - matter nerve damage similar to that seen in premature babies.

Using a surgical technique called parabiosis to join the circulatory system of a young mouse with that of an old one, the researchers studied the effects of young blood on elderly cells, and vice versa.

Meet Quill, a young mouse with dreams of greatness beyond the confines of her quiet forest settlement.

Quill, a young mouse with dreams of greatness, is called on an epic journey.

Not exact matches

There are the usual suspects, like pricey pills and supplements, as well as the peculiar, such as infusions of blood from young mice or standing - room chambers pumped with sub-zero temperatures.

The team found neonatal mice with the mutations had normal - appearing skin, and the dry itchy skin of dermatitis did not develop until the mice were a few months old, the equivalent of a young adult in human years.

As expected, young mice treated with THC performed slightly worse on behavioral tests of memory and learning.

With no more than a change in diet, laboratory agouti mice (left) were prompted to give birth to young (right) that differed markedly in appearance and disease susceptibility.

Specifically, the researchers found that a peptide, called STAT6 - IP, when delivered to the lungs of neonatal mice at the time of first RSV exposure reduces the development of allergic - type lung inflammation and airway hyperresponsiveness («twitchy» airways) in mice when they are «re-challenged» with RSV as young adults.

To find out more about what underlies the cognitive decline that occurs with ageing, André Fischer of the European Neuroscience Institute in Göttingen, Germany, and colleagues analysed DNA from the brains of both young and old mice that had been set tasks involving learning and memory.

For this procedure, a smaller, younger mouse is paired with a larger, older, and more aggressive mouse.

To make their discovery, scientists infected mice with RSV, first as infants and then again as young adults.

Part of the problem, he says, is that the incidence of many human chronic diseases rises with age, yet many researchers prefer using young mice because of the pressures of being published and getting funding.

In 2013, researchers reported that they were able to cure hypertrophy in mice by surgically merging the circulatory systems of an older mouse with a younger mouse.

«From other studies ***** we know that epigenetic modifications of the DPP4 gene, which are associated with an increased production of the enzyme, have a negative impact on the liver metabolism already in young mice, long before fatty liver disease emerges,» says Baumeier.

«The effects of young blood on cognition have not been replicated by an independent group, and there has never been a test with a mouse model of Alzheimer's.»

After 18 - month - old mice were treated with NMN for two months, their capillary density was restored to levels typically seen in young mice, and they experienced a 56 to 80 percent improvement in endurance.

Additionally, the researchers report online today in Cell, old mice injected with this protein for 30 days developed younger, stronger heart tissue.

In their research on young mice, for instance, all the subjects died when they were infected with the Nodamura virus, but when Ding's researchers removed the suppressor protein called B2 from the virus, the infected mice began producing huge armies of the virus - attacking siRNAs and lived, unaffected by the otherwise lethal infection.

GDF - 11, which regulates the growth of spinal and olfactory (smell) receptors, is produced abundantly in young mice, but production drops off with age.

The researchers then infected younger and older mice with the bacteria Streptococcus pneumoniae, which causes so - called pneumococcal pneumonia.

At young adulthood, Larsson's mice resembled those three times their age, with bone and muscle loss, heart disease — even baldness.

Its concentration was low and steady at young ages - within the known critical period for mice — and ramped up with age.

When she and Duarte raised the burying beetle larvae with germ - free mice, which lack any gut bacteria, the young did not grow as large as those buried with regular mice.

Three mice injected with the new synthetic EPO showed bursts in the numbers of young red blood cells that rivaled levels in those injected with Procrit, a commercial EPO.

«Vaccines protect fetuses from Zika infection, mouse study shows: Mothers vaccinated prior to pregnancy bore young with no sign of virus.»

When examined at the time of weaning, the young mice displayed reduced body weight, a symptom that has been associated with an increased risk of metabolic disease later in life.

He is quick to add, however, that even though the old female mice with newly viable eggs were allowed to cavort with young, studly mice, they did not produce offspring.

The breeders were either old (12 month) or young (3 month) males, each bred with two young (3 month) female mice.

Young mice paired with old mice (left chart, two - toned) made fewer new cells in the brain's hippocampus than when paired with another young mouse (yelYoung mice paired with old mice (left chart, two - toned) made fewer new cells in the brain's hippocampus than when paired with another young mouse (yelyoung mouse (yellow).

This artificial joining of two separate animals, known as parabiosis, was a staple of physiology experiments for over a century before Irina Conboy got the idea to pair an old mouse with a young one.

Enter a mutant mouse strain that is afflicted at a young age with many of the diseases common to older humans.

Old mice made hundreds more new brain cells when paired with a young mouse (right chart, two - toned) than when paired with an old mouse (teal).

Changes in muscle repair with aging were determined by injecting the old mice and young mice (neither group exercised) with snake venom commonly used to induce muscle injury in rodent studies.

The researchers harvested satellite cells from both healthy and injured muscle tissue of young mice and from healthy tissue of old mice; extracted these cells» DNA with the histone coatings intact; and used tagged antibodies targeting the different kinds of marks to find which spots on those histones were flagged with either «stop» or «go» signals.

The surprise came when Gewirtz's team infected the mice with rotavirus, a common cause of severe diarrhea in young children.

In one group of mice, he and his colleagues dosed their mothers with a synthetic compound that simulates a mild viral infection during late pregnancy; when their offspring hit early puberty at about 6 weeks of age, the young mice were exposed to unpredictable stress, such as being restrained, deprived of water, or given electric foot shocks.

Instead, they found, in quiescent satellite cells taken from the younger mice, copious instances in which histones in the vicinity of genes ordinarily reserved for other tissues were marked with both «stop» and «go» signals, just as genes associated with development to mature - muscle status were.

Interrupting their development with antibiotics disturbs the metabolism of young mice and boosts their risk of obesity later on.

It was one of the most mind - bending scientific reports in 2014: Injecting old mice with the plasma portion of blood from young mice seemed to improve the elderly rodents» memory and ability to learn.

Scientists have created a strain of mice with ovaries that essentially remain young until the animals die.

Vampire stories aside, the idea of rejuvenating the body with young blood dates back to macabre 1950s experiments that stitched young and old mice together so they shared a circulatory system.

Their younger cousins recovered fine, as did older mice with telomerase intact, but more than half of the aged, telomere - depleted mice died from the treatment.

But they also showed only continuous stimulation decreased the amount of time mice spent interacting with young mice, considered to be an undesirable side effect.

For example, Young's research shows normally monogamous prairie voles do not develop pair bonds with their mates if their mu - opioid system is blocked; other studies have found that mice genetically engineered to have no mu - opioid receptors do not prefer their mothers to other mice the way normal baby mice do.

The researchers compared their new mouse model with young mice that have immune system defects and are known to die several days after Zika infection.

A 36 - hour coculture of aged HSCs (from 18 - 24 month - old mice) with young MSCs (from 6 - 8 week - old mice) reversed signs of aging in HSCs

The researchers compared one group of mice that gave birth four times with a second group of mice that gave birth only once, some of these at the same age that the first group had its fourth litter and some at a younger age.