Using
zebrafish as a model system, the researchers exposed the fish embryos to seven different types of TAML activators.
121/4: 00 Cbx3 and its role in craniofacial development:
Zebrafish as a model system for testing dysmorphology candidate genes.
Not exact matches
More recently, Godinho Ferreira, who now employs three Ph.D. students and four postdocs, has been working to establish
Zebrafish as a new
model system to try and understand the role of telomeres in aging and the role of telomere - elongation enzymes in cancer.
We have been using cell culture
models and
zebrafish as an assay to determine the effects of BMP on signaling, but we also want to be able to understand what the effect of the mutation is in the tissue and organ
systems.
According to Monk and Ackerman, possible future work includes using the
zebrafish model system as a drug - screening tool to search for small molecules that may flip that switch.
«Organ development, especially the liver, is highly conserved among vertebrates — including
zebrafish — and the mutations we create in
zebrafish alter embryogenesis in a manner consistent with humans, making it an ideal
model system to study diseases such
as Alagille syndrome.»
Tobin, who helped to develop the
zebrafish as a
model of TB, decided to use the
system to study the blood vessels associated with granulomas.
So desirable is the
zebrafish as a scientific model that the National Institutes of Health recently launched the NIH Zebrafish Initiative Website, offering funding for studies of cancer, cardiovascular, blood and pulmonary diseases, eye development and disease, gene function, circadian rhythms, aging, longevity, immune system development and function, addiction, hearing, balance, smell a
zebrafish as a scientific
model that the National Institutes of Health recently launched the NIH
Zebrafish Initiative Website, offering funding for studies of cancer, cardiovascular, blood and pulmonary diseases, eye development and disease, gene function, circadian rhythms, aging, longevity, immune system development and function, addiction, hearing, balance, smell a
Zebrafish Initiative Website, offering funding for studies of cancer, cardiovascular, blood and pulmonary diseases, eye development and disease, gene function, circadian rhythms, aging, longevity, immune
system development and function, addiction, hearing, balance, smell and taste.
The
zebrafish is now a well - established
model system whereas
zebrafish research was mere small fry
as recently
as the 1990s.
Enriched by the rapid evolution of these technologies, TEFOR - TACGene has developed a solid expertise in the design, production and use of TALE - N and CRISPR / Cas9
systems, both for its own research projects in cultured cells and in collaboration, in many
model organisms, including the rat,
zebrafish, Drosophila, and Xenopus
as part of the National Infrastructure in Biology and Health TEFOR supported by Investissement d'Avenir programme (2012 - 2019).
His group uses the
zebrafish (Danio rerio)
as a
model system to study various processes.