Sentences with phrase «zebrafish development»

His research on the reconstruction of zebrafish development was selected for the «Top Five Scientific Breakthroughs of 2008» by The Times (Dec 19, 2008) and for the «Top Ten Scientific Breakthroughs of 2008» by Science (322:1768 - 73).

Multiple embryo time - lapse imaging of zebrafish development.

Patricia Heyn (Neugebauer, MPG)-- «Nuclear architecture and gene expression during early zebrafish development» (2013)

Having spent his first 5 years in that position establishing his own research theme and tools to study zebrafish development, «now it is thanks to this programme that I can expand and fully develop it.»

Two other members of this family, Ndr1 and Ndr2, are required to form the mesoderm and endoderm early in zebrafish development.

«Thus, we hypothesize that Gdf3 combines with Ndr1 and Ndr2 to facilitate Nodal signaling during zebrafish development, acting as an essential factor in embryonic patterning,» said Pelliccia, a graduate student in molecular biology.

Forthcoming workshops cover techniques as varied as «molecular and genetic tools for the analysis of medaka and zebrafish development» and «cryo - electron microscopy and 3 - D image reconstruction.»

Not exact matches

«BPA and BPS (substitute for BPA) affect embryonic brain development in zebrafish: Low levels of chemicals linked to hyperactivity.»

He could observe never - before - seen instances of zebrafish embryo development, and the formation of germ layers.

In the initial stages of the research project, Yaniv's team members Julian Nicenboim and Dr. Guy Malkinson obtained images of developing zebrafish embryos, whose transparent bodies make it possible to document embryonic development in real time over several days.

For the study, the researchers created a line of zebrafish with defective immune systems by inserting a mutation into a gene required for development of an important component of the immune system.

In experiments on zebrafish, Freiburg researchers have demonstrated that the same proteins that lead to the formation of metastases in humans also cause the cells to migrate during embryonic development.

The study found that zebrafish that failed to inherit specific genetic instructions from mom developed fatal defects earlier in development, even if the fish could make their own version of the gene.

Using embryos of zebrafish, which was selected for its rapid development and optical transparency, they could show that the mechanical properties of the tissue change along the body axis, facilitating the extension of the body at its posterior end.

Different types of studies use different stand - ins: Flies for genetics; zebrafish for early development; rats and mice and monkeys for cancer, neuroscience and more.

Glowing red, green and blue, the nerve fibers in this five - day - old zebrafish provide a map of early brain development.

Investigators at Duke University, led by Erica Davis, PhD, a co-senior author of the report, blocked the gene's expression in zebrafish, which resulted in abnormal facial cartilage, smaller eyes and structural abnormalities of neurons involved in the development of reproductive organs.

Research in the laboratory of Rebecca Wingert, the Gallagher Family Associate Professor of Adult Stem Cell Research in the Department of Biological Sciences at the University of Notre Dame, has confirmed the key role of a certain small molecule in the development of kidney structures in zebrafish, a widely used model for human kidneys.

The results from McCammon's initial screen with zebrafish indicate that two genes in the 16p11.2 region could be key for brain development: fam57ba and doc2a.

When Kaufman, Zon and colleagues looked to see what was different about these early cancer cells, they found that crestin and the other activated genes are the same ones turned on during zebrafish embryonic development — specifically, in the stem cells that give rise to the pigment cells known as melanocytes, within a structure called the neural crest.

The study imaged live zebrafish over time to track the development of melanoma.

Dr. Lyons and his team used zebrafish to study the formation of myelin sheaths by oligodendrocytes because this laboratory animal is transparent at early stages of its development, which allows investigators to directly observe cells within the organism.

Zebrafish have emerged as an important vertebrate model for cardiovascular research for a number of reasons, including the ability to regenerate its heart if damaged, and because the transparency of the embryos allows easy observation of internal processes like blood vessel development.

To get a better idea of the gene's role in development the researchers blocked the expression of the gene in zebrafish.

A novel drug screening platform for zebrafish brain tumors was then designed to identify drugs that could eliminate brain tumors without affecting development of the normal brain.

«It is interesting to think that backbone development in sharks and skates is more similar to humans than it is to bony fishes like zebrafish and salmon.

Using the CAGE (Cap Analysis of Gene Expression) high - throughput method, the scientists determined the starting points of transcription of many thousands of genes in various phases of embryonic development of zebrafish.

For the first time, it is now found by a study that various mechanisms of transcribing DNA into RNA exist during gene expression in the different development phases of zebrafish.

The zebrafish is used as a model organism for research into the embryonic development of vertebrates.

Inside the spinal cord of a zebrafish embryo, new neurons light up in different colors, letting scientists track nerve circuit development.

Specific types of bacteria may have well - defined roles in shaping development of the zebrafish digestive tract (highlighted in these images).

In raising the first germ - free zebrafish, the team has produced «extremely powerful tools for examining the influence of beneficial bacteria on animal development,» says microbiologist Margaret McFall - Hgai of Kewalo Marine Laboratory in Honolulu, Hawaii.

In zebrafish, an organism scientists use to study development, sulfilimine bonds are required for organs to form, Hudson's team reports December 16 in the Proceedings of the National Academy of Sciences.

Now research with tiny, transparent zebrafish suggests that some of these bugs do more: altering the activity of individual genes in their host, and potentially shaping the fish's development and physiology.

«Organ development, especially the liver, is highly conserved among vertebrates — including zebrafish — and the mutations we create in zebrafish alter embryogenesis in a manner consistent with humans, making it an ideal model system to study diseases such as Alagille syndrome.»

Zebrafish (pictured above) are often used as a model for studying vertebrate development.

A paper on the work, «Prostaglandin signaling regulates nephron segment patterning of renal progenitors during zebrafish kidney development,» was published in the journal eLife this week.

The objective is to support innovative projects dedicated to the development and the study of rare disease models using small animals (mouse model excepted) such as zebrafish, drosophila, nematode, rat and rabbit.

Here, the authors leveraged a zebrafish model system to examine the role of that enhancer during development.

Zebrafish is an ideal model for extending the scope of genomics to vertebrate development.

We aim to comprehensively annotate functional elements, decipher genomic codes of transcription, as well as coding and non-coding gene function during development and enhance zebrafish as an attractive developmental, comparative and disease model.

Zebrafish also express this gene, and the study showed that it plays a crucial role in embryonic development.

Combining the advantage of zebrafish larvae being transparent with the latest developments in video analysis technologies, results in a much more efficient and less invasive method.

DanioVision is a complete system designed for exactly these types of experiments with zebrafish larvae, and is often used in studies related to drug development, safety pharmacology, behavioral genetics, and circadian rhythmicity.

Identification and Expression Analysis of Zebrafish Glypicans during Embryonic Development.

The external and easily visualized development also makes zebrafish well suited to study the biological effect of chemical compounds.

We use the zebrafish model to study β - cell development due to the small size and optical transparency of its embryos / larvae, as well as the ease of the genetic and chemical - genetic manipulations, including the ability to conduct large - scale small molecule screens.

Elena Quesada Hernandez (Heisenberg, MPG)-- «The role of cell division orientation during zebrafish early development» (2011)

With the first spontaneous movements taking place as early as 17 hours post-fertilization and swimming behavior occuring after 27 hours, zebrafish embryos prove to be a good model for the study of development of locomotor activity.

Zebrafish are a logical subject choice in the study of neural development for many scientists.