He could observe never - before - seen instances of
zebrafish embryo development, and the formation of germ layers.
Not exact matches
In the initial stages of the research project, Yaniv's team members Julian Nicenboim and Dr. Guy Malkinson obtained images of developing
zebrafish embryos, whose transparent bodies make it possible to document embryonic
development in real time over several days.
Using
embryos of
zebrafish, which was selected for its rapid
development and optical transparency, they could show that the mechanical properties of the tissue change along the body axis, facilitating the extension of the body at its posterior end.
Zebrafish have emerged as an important vertebrate model for cardiovascular research for a number of reasons, including the ability to regenerate its heart if damaged, and because the transparency of the
embryos allows easy observation of internal processes like blood vessel
development.
Inside the spinal cord of a
zebrafish embryo, new neurons light up in different colors, letting scientists track nerve circuit
development.
We use the
zebrafish model to study β - cell
development due to the small size and optical transparency of its
embryos / larvae, as well as the ease of the genetic and chemical - genetic manipulations, including the ability to conduct large - scale small molecule screens.
With the first spontaneous movements taking place as early as 17 hours post-fertilization and swimming behavior occuring after 27 hours,
zebrafish embryos prove to be a good model for the study of
development of locomotor activity.
«Discovery of a gene that could convert human embryonic stem cells into myocardial cells would be golden,» said Didier Stainier, PhD, UCSF assistant professor of biochemistry and biophysics, the senior author of the UCSF study and a pioneer in the study of heart
development in the transparent
zebrafish embryo.
Multiple
embryo time - lapse imaging of
zebrafish development.
In this study, the team delved deep into the nucleus of cells belonging to mouse and
zebrafish embryos — two important animal models of embryonic
development — in order to determine how the Dll4 gene is turned on.
Zebrafish embryo spinal cord neural circuit
development (credit: HHMI Howard Hughes Medical Institute)
Like the African clawed frog, the
zebrafish — with its free - swimming, transparent
embryos — has been used extensively in the study of
development, especially since the 1990s.