Mitotic position and morphology of committed precursor cells in
the zebrafish retina adapt to architectural changes upon tissue maturation.
We use
the zebrafish retina as our main model.
Sarah Hochmann (Brand, TUD)-- «The role of Fgf signaling in photoreceptor maintenance and degeneration in the adult
zebrafish retina» (2011)
Lane 1: HEK cells Lane 2: hfRPE cells Lane 3: hfRetina Lane 4: Mouse liver Lane 5: Mouse RPE Lane 6: Mouse retina Lane 7: Zebrafish liver Lane 8:
Zebrafish retina PVDF membrane RIPA lysis buffer with mixed phosphatase and protease inhibitor cocktail
This is possible because
the zebrafish retina contains cells called Müller glia that harbor a gene that allows them to regenerate.
A:
Zebrafish retinas at 3 days - post-fertilization (dpf).
Not exact matches
In
zebrafish they can undergo changes if the
retina is injured.
This is not the case, however, in
zebrafish, which have a remarkable ability to regenerate damaged tissue, including neural tissue like the
retina.
«Regenerative potential of cells in mouse
retina: Researchers use a clue from
zebrafish to discover the cues that reprogram Müller glia into retinal neurons.»
OIST scientists selected the
zebrafish as an animal model because its
retina is rich in cones and its visual acuity can be measured with a simple device.