Sentences with phrase «zebrafish showed»

Recent studies on species such as zebrafish showed scales and teeth developing from distinctly different clusters of cells in fish embryos, pouring cold water on «teeth from scales» theories.

More than 200 genes in the germ - free zebrafish showed levels of activity different than those in their bacteria - exposed cousins.

New research from a team including Carnegie's Daniel Gorelick and Marnie Halpern on the effects of these chemicals on zebrafish shows that embryonic heart valves could be particularly in danger.

Not exact matches

Testing the titanium sub-oxides on zebrafish (the aquatic cousin of lab rats) showed it to be toxic when ingested; the toxicity was significant in tissue not exposed to sunlight.

They found that the TAML - treated BPA water did not show estrogen activity or cause abnormalities in yeast and developing zebrafish embryos.

Zebrafish that stop swimming when left without company are showing promise as the first fish model of a human mood disorder.

Using embryos of zebrafish, which was selected for its rapid development and optical transparency, they could show that the mechanical properties of the tissue change along the body axis, facilitating the extension of the body at its posterior end.

Taking the example of cocaine, researchers at Eawag, together with colleagues at Zurich University, have now shown that the uptake and distribution patterns and the effects of the drug in zebrafish differ in many ways from those in mammals.

When the scientists inserted human colorectal cancer cells into zebrafish embryos and allowed them to grow for 4 days, the resulting tumors showed three hallmarks of human solid tumors: rapid cell division, formation of blood vessels to supply nutrients, and the ability to spread to other locations in the body.

By chemically removing the gut microbiome in zebrafish in the lab and then repopulating the gut with two to three bacterial species, University of Oregon biologist Karen Guillemin has shown that certain microbes are especially skilled at suppressing the host immune system and preventing inflammation — a discovery she thinks may have implications for human health.

In analyses of 23 videos of five different types of animals (mice, fruit flies, ants, zebrafish [shown], and small tropical fish called medaka), the software was able to identify and correctly track individuals (color - coded trails) within those groups 99.7 % of the time, researchers report online today in Nature Methods.

This is a developing zebrafish skeleton showing Sox9 activates a green fluorescent protein reporter in chondrocytes.

«Now, through our new study, we show that lowering levels of a particular cohesin protein called Rad21 in embryonic zebrafish produces similar types of heart defects to those found in people with CdLS,» Associate Professor Horsfield says.

Similar to zebrafish, mice in which Lef1 had been removed from the hypothalamus showed signs of anxiety, including being smaller and a reluctance to explore.

Photo of a living Brainbow zebrafish, taken by Zachary Tobias (a research technician in Weissman - Unni's lab), showing a brightly labeled neuron with its cell body (white) at bottom.

«The research carried out in zebrafish unit of the University of Helsinki showed that in addition to cell cultures, these optogenetic tools worked also in living tissues,» says Academy Research Fellow Jari Rossi.

This is an image of an adult zebrafish brain showing fluorescent granular perithelial cells (green) atop blood vessels (green).

In the current study, the researchers showed that FGPs are present on the surface of the zebrafish brain and that these blood vessel - associated FGPs do not arise from the immune system, as had been previously thought, but from endothelial cells themselves.

To show their program's promise beyond plant roots, the researchers also used it with a different microscope to watch groups of cells move around in growing zebrafish (Danio rerio) embryos.

Ruvkun's work showed that a microRNA called let - 7 regulates maturation from the larval stage to adulthood — and that it operates in many creatures, from fruit flies to zebrafish to mollusks.

The upper image is a three - day - old zebrafish larva showing activation of green fluorescent protein expression in the liver (arrow) following exposure to an estrogenic compound.

Gorelick, the lead author, Halpern and Alice Hung of Carnegie, along with Luke Iwanowicz and Vicki Blazer of the Fish Health Branch of the U.S. Geological Survey, used genetically modified zebrafish that show estrogen receptor activity on a cell's DNA.

The ability to grow a new limb may seem like something straight out of science fiction, but new research shows exactly how animals like salamanders and zebrafish perform this stunning feat — and how humans may share the biological machinery that lets them do it.

But research by others has shown that zebrafish scales are more related to the musculoskeletal system, rather than the tissues that form teeth.

«We studied a zebrafish gene that is analogous to a human gene that causes deafness, and here we show the defect is in the process of mechanotransduction.»

«Epilepsy drug discovered in fish model shows promise in small pediatric clinical trial: Research suggests zebrafish models may be efficient resource for identifying drugs for clinical use.»

But a new study shows that zebrafish tails have their own organizing blueprint and are assembled independently of the head and body.

«These findings show that tissue regeneration in African spiny mice is similar to that described for other vertebrate regenerators like salamanders and zebrafish, giving us a powerful framework to understand mammalian regeneration,» said Seifert.

Cardiac Edema and Cranial Injuries Laboratory experiments involving zebrafish have previously shown that oil pollution causes the larvae to develop cardiac edema.

Study results published online in the journal Green Chemistry show that the molecules, which are aimed at removing hazardous endocrine disruptors from water sources, aren't endocrine disruptors themselves as they proved to be non-toxic to developing zebrafish embryos.

Microinjection of wild - type human ACVR1 RNA into alk8 — / — zebrafish embryos rescued approximately 80 % of the injected embryos completely or partially (Figure 3, C and F), showing that human ACVR1 can function as a BMP type I receptor in this zebrafish model and substitute for Alk8.

«Using different genetic techniques, we inhibited Wars2 function in both rats and zebrafish, and the resulting animals showed impairment of blood vessel formation within the heart and in the rest of the body,» described Mr Wang.

Below is a short video of the current system showing the anatomically correct zebrafish brain regions in 3D.

In the current study, two of the amino acid differences that Cheng has shown in prior studies to contribute to light skin color in humans prevented the zebrafish color from darkening.

Interestingly, the zebrafish assay did not show epithelial enhancer activity for the +105 kb element by itself.

Specifically, in [12], it is shown that zebrafish responds differentially to variation in aspect ratio and color in the robotic fish; in [13], it is demonstrated that zebrafish shoals prefer such a robotic fish to an empty compartment; in [14], it is demonstrated that an interactive robot, whose tail - beat frequency responds to fish position, is able to induce preference among single organisms; and in [17], it is shown that the robotic fish is able to simultaneously attract shoals of zebrafish while repelling shoals of mosquitofish that would otherwise display aggressive behavior.

ABC7 / Fox 22 interviews MDI Biological Laboratory scientist Voot P. Yin, Ph.D., about MSI - 1436, a drug candidate that has been shown to stimulate the regeneration of heart muscle tissue in zebrafish and mice.

How zebrafish embryos react to the manipulation of certain compounds (e.g. Ahmad et al., 2012) is measured by the kind of activity they show.

Zebrafish also express this gene, and the study showed that it plays a crucial role in embryonic development.

Currently, zebrafish are showing real promise in heart failure research because zebrafish have the unique ability to repair their own heart muscle.

SPECIES COMPARISON: This circular genome map shows shared genetic material between humans (outer ring) and (from inner ring outwards) chimpanzee, mouse, rat, dog, chicken, and zebrafish chromosomes.

On the other hand, the present research work shows a confirmatory evidence of the potential of kahweol to inhibit in vivo angiogenesis, by using another completely independent model system, namely, that of genetically modified zebrafish.

Scientists have released video showing immune cell migration in the Zebrafish inner ear.

In the supplementary material, Video S1 shows clearly a continuous blood flow along intersegmentals vessel of control zebrafish larvae.

In the JBC article, Lipschutz and his MUSC coauthors go a step further — showing in cell culture and a zebrafish model that depletion of Tuba, a guanine nucleotide exchange factor required for Cdc42 activation, also disrupts renal ciliogenesis.

In randomized experimental and data analysis protocols, MSI - 1346 has been shown to regenerate heart, connective, nerve, skin, bone and vascular tissues in adult zebrafish.

Experiments on both larval zebrafish, a model for salmon, and actual coho salmon showed that toxic runoff can also damage hair - like sensors the fish use to find food, sense predators, and find their way in the current.

The two components of Cas9 / gRNA have shown high DNA cleavage activity in cultured cells [6], [7], C. elegans [10], zebrafish [11] mice [12] and pigs [13].

Whitehead Institute scientists have identified conserved, long intervening non-coding RNAs (lincRNAs) that play key roles during brain development in zebrafish, and went on to show that the human versions of these RNAs can substitute for the zebrafish lincRNAs.

Intensity as recorded in zebrafish (crosshairs in Fig. 4a show where measurement took place) at an excitation wavelength of 633 nm and scanned for emission at 11 nm intervals from 654 nm to 794 nm.