Both teams designed
zinc finger molecules that would stick to the «CAG tract» of the huntingtin gene, and tell cells not to read the gene.
What's more, these synthetic
zinc finger molecules can be tweaked and packaged with other drugs, to produce multi-purpose DNA - binding tools that can stick, slice, glue and block.
Not exact matches
These include a family of signaling
molecules called protocaderins, which regulate neuronal development and short - range interactions between neurons, and a family of transcription factors called
zinc fingers, which are mainly expressed in embryonic and nervous tissues and are thought to play roles in brain development.