For the other two thirds of the participants (12/18), serum
zonulin levels fluctuated significantly between blood samples.
But gluten is gluten, and even if you're not celiac — now there is research that shows that celiacs are gonna have30 times higher
zonulin levels than a non-celiac.
For example, a close look at the data from one study finds that only 42 percent of the patients with type 1 diabetes had an elevated serum
zonulin level (defined as 2 standard deviations above the control group mean)(13).
Not exact matches
However, even in healthy individuals, biopsies reveal a transient
zonulin release upon gluten ingestion accompanied by an increase in intestinal permeability that does not reach the
level observed in celiac disease (Drago et al., 2006).
First, in many of these studies I listed in the previous section linking elevated
zonulin with disease, only a fraction of the patients with the condition showed elevated
levels of
zonulin.
When Vojdani et al. measured IgG and IgA antibody
levels against
zonulin at the same time points (zero, six, 24, and 30 hours), they found that serum
zonulin was somewhat correlated with anti-
zonulin IgG and highly correlated with anti-
zonulin IgA.
High
levels of
zonulin can be which can be triggered by gluten, parasites, candida, and harmful bacteria.
Abnormally high
levels of
zonulin, can cause these openings to become too large and permeable.