Synonyms for «biggest causes»

largest greatest huge major massive worst best leading top significant important chief several various main possible wide strongest numerous potential common causal ultimate foremost multiple different primary driving medical health hardest whole obvious risk fundamental countless underlying environmental contributing root climate principal real key global second serious single natural

reasons causation factors triggers effects disease issues cancer injuries problem culprit motivation conditions influence events challenges source mistakes motivator explanation threat stressors force things impact hazards fixes concern people danger death mechanism crisis killer stress contributor driver result trouble obstacle growth accident complaints variety couple change damage part question