The phrase
"major roadblock" means a significant obstacle or barrier that hinders progress or prevents someone from achieving a goal.
Full definition
Synonyms for individual words can be found below.
«major»
«roadblock»
Sentences with «major roadblock»
- Recent evidence suggests that one major roadblock for the effective use of immunotherapies in pancreatic cancer patients is that the tumors are effectively hidden, preventing the immune system from recognizing and killing them. (pancreaticcancercollective.org)
- One major roadblock in their progress is the lack of understanding of the role that dark matter plays in the formation and interaction of galaxies. (astronomynotes.com)
- Huawei has tried time and time again to get into the US, but it faces a lot of major roadblocks to getting in front of consumers. (9to5google.com)
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sentences)