The word "pathogenicity" refers to the ability of a microorganism, such as a bacteria or virus, to cause disease or harm to its host. It describes how likely a particular pathogen is to cause illness in the organism it infects. Full definition
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Of the genes that were found to exhibit variable patterns of presence and absence, those that encoded toxins were the most notable, including some Toxin - Antitoxin systems (TA), such as vapBC, higAB, relEK, relEB, hicAB and some unnamed TAs, widely reported among Proteobacteria, regulating normal physiological processes but also involved in pathogenicity of bacteria (29,30). (jgenomics.com)
The invasion of epithelial cells and immune cells are controlled by two separate gene clusters called Salmonella Pathogenicity Islands 1 and 2 (SPI1, SPI2) respectively. (sciencedaily.com)
Given their in vivo role in pathogenicity, and based on the yeast two - hybrid interaction data, these results point to the importance of these pathogen proteins in modulating host ubiquitination pathways, phagosomal escape, and actin - cytoskeleton rearrangement processes. (jcvi.org)