A "setback" refers to an obstacle, difficulty, or delay that hinders progress or success in achieving a goal or plan. It is something that sets you back or holds you back from moving forward smoothly. Full definition
It was just the latest in a string of major setbacks for tar sands oil, which has become nearly as bad for corporate profits as it is for the environment. (resilience.org)
Many people suffer financial setbacks in their lives and an auto loan modification may help a person's financial situation. (autos.com)
But it was only the latest in a series of setbacks for climate legislation. (salon.com)