Synonyms for «worst issue»

Synonyms for individual words can be found below.

I have a really bad issue with food and not eating.. (sarahvarno.com)
While this sounds green we feel the reality is there are many bad issues in doing this and no good ones. (co2insanity.com)
When it first came out the game had some really bad issues on consoles making it a rough experience for all involved. (articles.gamerheadquarters.com)
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