«While FL118 is an analogue of irinotecan and topotecan, two FDA - approved cancer drugs that are also based on the naturally occurring compound camptothecin, our findings add further evidence that FL118 has novel mechanisms of action that may make it especially potent against solid tumors and especially effective as a well - tolerated, targeted therapy,» said Dr. Li, an Associate Professor of Oncology in the Department of Pharmacology and Therapeutics. (sciencedaily.com)
Tests on laboratory animals with a type of experimental leukemia... have shown that the extract, known as camptothecin, has high antitumor properties. (sciencenews.org)
Although it didn't prove effective against leukemia, a synthetic version of camptothecin is used to treat ovarian, lung and (sciencenews.org)